BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 25339176)

  • 1. Activation of glycogen synthase kinase 3β ameliorates diabetes-induced kidney injury.
    Mariappan MM; Prasad S; D'Silva K; Cedillo E; Sataranatarajan K; Barnes JL; Choudhury GG; Kasinath BS
    J Biol Chem; 2014 Dec; 289(51):35363-75. PubMed ID: 25339176
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Glycogen synthase kinase 3beta is a novel regulator of high glucose- and high insulin-induced extracellular matrix protein synthesis in renal proximal tubular epithelial cells.
    Mariappan MM; Shetty M; Sataranatarajan K; Choudhury GG; Kasinath BS
    J Biol Chem; 2008 Nov; 283(45):30566-75. PubMed ID: 18701453
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reciprocal regulation of miR-214 and PTEN by high glucose regulates renal glomerular mesangial and proximal tubular epithelial cell hypertrophy and matrix expansion.
    Bera A; Das F; Ghosh-Choudhury N; Mariappan MM; Kasinath BS; Ghosh Choudhury G
    Am J Physiol Cell Physiol; 2017 Oct; 313(4):C430-C447. PubMed ID: 28701356
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells.
    Lee HJ; Mariappan MM; Feliers D; Cavaglieri RC; Sataranatarajan K; Abboud HE; Choudhury GG; Kasinath BS
    J Biol Chem; 2012 Feb; 287(7):4451-61. PubMed ID: 22158625
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanical regulation of glycogen synthase kinase 3β (GSK3β) in mesenchymal stem cells is dependent on Akt protein serine 473 phosphorylation via mTORC2 protein.
    Case N; Thomas J; Sen B; Styner M; Xie Z; Galior K; Rubin J
    J Biol Chem; 2011 Nov; 286(45):39450-6. PubMed ID: 21956113
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mitochondrial aldehyde dehydrogenase (ALDH2) protects against streptozotocin-induced diabetic cardiomyopathy: role of GSK3β and mitochondrial function.
    Zhang Y; Babcock SA; Hu N; Maris JR; Wang H; Ren J
    BMC Med; 2012 Apr; 10():40. PubMed ID: 22524197
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High glucose forces a positive feedback loop connecting Akt kinase and FoxO1 transcription factor to activate mTORC1 kinase for mesangial cell hypertrophy and matrix protein expression.
    Das F; Ghosh-Choudhury N; Dey N; Bera A; Mariappan MM; Kasinath BS; Ghosh Choudhury G
    J Biol Chem; 2014 Nov; 289(47):32703-16. PubMed ID: 25288788
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PDGF receptor-β uses Akt/mTORC1 signaling node to promote high glucose-induced renal proximal tubular cell collagen I (α2) expression.
    Das F; Ghosh-Choudhury N; Venkatesan B; Kasinath BS; Ghosh Choudhury G
    Am J Physiol Renal Physiol; 2017 Aug; 313(2):F291-F307. PubMed ID: 28424212
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice.
    Huang SL; Xie W; Ye YL; Liu J; Qu H; Shen Y; Xu TF; Zhao ZH; Shi Y; Shen JH; Leng Y
    Acta Pharmacol Sin; 2023 Mar; 44(3):596-609. PubMed ID: 36085523
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Soluble epoxide hydrolase inhibition ameliorates proteinuria-induced epithelial-mesenchymal transition by regulating the PI3K-Akt-GSK-3β signaling pathway.
    Liang Y; Jing Z; Deng H; Li Z; Zhuang Z; Wang S; Wang Y
    Biochem Biophys Res Commun; 2015 Jul 17-24; 463(1-2):70-5. PubMed ID: 25986738
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hydrophobic motif site-phosphorylated protein kinase CβII between mTORC2 and Akt regulates high glucose-induced mesangial cell hypertrophy.
    Das F; Ghosh-Choudhury N; Mariappan MM; Kasinath BS; Choudhury GG
    Am J Physiol Cell Physiol; 2016 Apr; 310(7):C583-96. PubMed ID: 26739493
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tadalafil Integrates Nitric Oxide-Hydrogen Sulfide Signaling to Inhibit High Glucose-induced Matrix Protein Synthesis in Podocytes.
    Lee HJ; Feliers D; Mariappan MM; Sataranatarajan K; Choudhury GG; Gorin Y; Kasinath BS
    J Biol Chem; 2015 May; 290(19):12014-26. PubMed ID: 25752605
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glycogen synthase kinase-3 inhibition attenuates fibroblast activation and development of fibrosis following renal ischemia-reperfusion in mice.
    Singh SP; Tao S; Fields TA; Webb S; Harris RC; Rao R
    Dis Model Mech; 2015 Aug; 8(8):931-40. PubMed ID: 26092126
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quercetin inhibits the mTORC1/p70S6K signaling-mediated renal tubular epithelial-mesenchymal transition and renal fibrosis in diabetic nephropathy.
    Lu Q; Ji XJ; Zhou YX; Yao XQ; Liu YQ; Zhang F; Yin XX
    Pharmacol Res; 2015 Sep; 99():237-47. PubMed ID: 26151815
    [TBL] [Abstract][Full Text] [Related]  

  • 15. GSK-3 directly regulates phospho-4EBP1 in renal cell carcinoma cell-line: an intrinsic subcellular mechanism for resistance to mTORC1 inhibition.
    Ito H; Ichiyanagi O; Naito S; Bilim VN; Tomita Y; Kato T; Nagaoka A; Tsuchiya N
    BMC Cancer; 2016 Jul; 16():393. PubMed ID: 27387559
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Troglitazone ameliorates high glucose-induced EMT and dysfunction of SGLTs through PI3K/Akt, GSK-3β, Snail1, and β-catenin in renal proximal tubule cells.
    Lee YJ; Han HJ
    Am J Physiol Renal Physiol; 2010 May; 298(5):F1263-75. PubMed ID: 20015942
    [TBL] [Abstract][Full Text] [Related]  

  • 17. mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition.
    Bhaskar PT; Nogueira V; Patra KC; Jeon SM; Park Y; Robey RB; Hay N
    Mol Cell Biol; 2009 Sep; 29(18):5136-47. PubMed ID: 19620286
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Melatonin ameliorates high fat diet-induced diabetes and stimulates glycogen synthesis via a PKCzeta-Akt-GSK3beta pathway in hepatic cells.
    Shieh JM; Wu HT; Cheng KC; Cheng JT
    J Pineal Res; 2009 Nov; 47(4):339-44. PubMed ID: 19817973
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of PI3K-Akt-GSK3beta pathway mediates hepatocyte growth factor inhibition of RANTES expression in renal tubular epithelial cells.
    Gong R; Rifai A; Dworkin LD
    Biochem Biophys Res Commun; 2005 Apr; 330(1):27-33. PubMed ID: 15781227
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intracellular signaling pathways regulating net protein balance following diaphragm muscle denervation.
    Argadine HM; Mantilla CB; Zhan WZ; Sieck GC
    Am J Physiol Cell Physiol; 2011 Feb; 300(2):C318-27. PubMed ID: 21084642
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.