273 related articles for article (PubMed ID: 25341037)
1. SIRT1 and SIRT2 inhibition impairs pediatric soft tissue sarcoma growth.
Ma L; Maruwge W; Strambi A; D'Arcy P; Pellegrini P; Kis L; de Milito A; Lain S; Brodin B
Cell Death Dis; 2014 Oct; 5(10):e1483. PubMed ID: 25341037
[TBL] [Abstract][Full Text] [Related]
2. Expression of sirtuin 1 and 2 is associated with poor prognosis in non-small cell lung cancer patients.
Grbesa I; Pajares MJ; Martínez-Terroba E; Agorreta J; Mikecin AM; Larráyoz M; Idoate MA; Gall-Troselj K; Pio R; Montuenga LM
PLoS One; 2015; 10(4):e0124670. PubMed ID: 25915617
[TBL] [Abstract][Full Text] [Related]
3. Functional characterization of NAD dependent de-acetylases SIRT1 and SIRT2 in B-Cell Chronic Lymphocytic Leukemia (CLL).
Bhalla S; Gordon LI
Cancer Biol Ther; 2016; 17(3):300-9. PubMed ID: 26794150
[TBL] [Abstract][Full Text] [Related]
4. Expression/localization patterns of sirtuins (SIRT1, SIRT2, and SIRT7) during progression of cervical cancer and effects of sirtuin inhibitors on growth of cervical cancer cells.
Singh S; Kumar PU; Thakur S; Kiran S; Sen B; Sharma S; Rao VV; Poongothai AR; Ramakrishna G
Tumour Biol; 2015 Aug; 36(8):6159-71. PubMed ID: 25794641
[TBL] [Abstract][Full Text] [Related]
5. Tenovin-D3, a novel small-molecule inhibitor of sirtuin SirT2, increases p21 (CDKN1A) expression in a p53-independent manner.
McCarthy AR; Sachweh MC; Higgins M; Campbell J; Drummond CJ; van Leeuwen IM; Pirrie L; Ladds MJ; Westwood NJ; Laín S
Mol Cancer Ther; 2013 Apr; 12(4):352-60. PubMed ID: 23322738
[TBL] [Abstract][Full Text] [Related]
6. SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2.
Peck B; Chen CY; Ho KK; Di Fruscia P; Myatt SS; Coombes RC; Fuchter MJ; Hsiao CD; Lam EW
Mol Cancer Ther; 2010 Apr; 9(4):844-55. PubMed ID: 20371709
[TBL] [Abstract][Full Text] [Related]
7. A novel sirtuin 2 (SIRT2) inhibitor with p53-dependent pro-apoptotic activity in non-small cell lung cancer.
Hoffmann G; Breitenbücher F; Schuler M; Ehrenhofer-Murray AE
J Biol Chem; 2014 Feb; 289(8):5208-16. PubMed ID: 24379401
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of the NAD-dependent protein deacetylase SIRT2 induces granulocytic differentiation in human leukemia cells.
Sunami Y; Araki M; Hironaka Y; Morishita S; Kobayashi M; Liew EL; Edahiro Y; Tsutsui M; Ohsaka A; Komatsu N
PLoS One; 2013; 8(2):e57633. PubMed ID: 23460888
[TBL] [Abstract][Full Text] [Related]
9. Tenovin-6-mediated inhibition of SIRT1/2 induces apoptosis in acute lymphoblastic leukemia (ALL) cells and eliminates ALL stem/progenitor cells.
Jin Y; Cao Q; Chen C; Du X; Jin B; Pan J
BMC Cancer; 2015 Apr; 15():226. PubMed ID: 25884180
[TBL] [Abstract][Full Text] [Related]
10. SIRT1 is upregulated in cutaneous T-cell lymphoma, and its inhibition induces growth arrest and apoptosis.
Nihal M; Ahmad N; Wood GS
Cell Cycle; 2014; 13(4):632-40. PubMed ID: 24343700
[TBL] [Abstract][Full Text] [Related]
11. Current advances in the synthesis and antitumoral activity of SIRT1-2 inhibitors by modulation of p53 and pro-apoptotic proteins.
Botta G; De Santis LP; Saladino R
Curr Med Chem; 2012; 19(34):5871-84. PubMed ID: 22998567
[TBL] [Abstract][Full Text] [Related]
12. SIRT1 deacetylase is overexpressed in human melanoma and its small molecule inhibition imparts anti-proliferative response via p53 activation.
Wilking MJ; Singh C; Nihal M; Zhong W; Ahmad N
Arch Biochem Biophys; 2014 Dec; 563():94-100. PubMed ID: 24751483
[TBL] [Abstract][Full Text] [Related]
13. Javamide-I-O-methyl ester increases p53 acetylation and induces cell death via activating caspase 3/7 in monocytic THP-1 cells.
Park JB
Phytomedicine; 2016 Dec; 23(13):1647-1652. PubMed ID: 27823629
[TBL] [Abstract][Full Text] [Related]
14. Hit-to-lead optimization on aryloxybenzamide derivative virtual screening hit against SIRT.
Yagci S; Gozelle M; Kaya SG; Ozkan Y; Aksel AB; Bakar-Ates F; Dundar Y; Eren G
Bioorg Med Chem; 2021 Jan; 30():115961. PubMed ID: 33360574
[TBL] [Abstract][Full Text] [Related]
15. The sirtuin 1/2 inhibitor tenovin-1 induces a nonlinear apoptosis-inducing factor-dependent cell death in a p53 null Ewing's sarcoma cell line.
Marx C; Marx-Blümel L; Lindig N; Thierbach R; Hoelzer D; Becker S; Wittig S; Lehmann R; Slevogt H; Heinzel T; Wang ZQ; Beck JF; Sonnemann J
Invest New Drugs; 2018 Jun; 36(3):396-406. PubMed ID: 29150734
[TBL] [Abstract][Full Text] [Related]
16. Salermide up-regulates death receptor 5 expression through the ATF4-ATF3-CHOP axis and leads to apoptosis in human cancer cells.
Liu G; Su L; Hao X; Zhong N; Zhong D; Singhal S; Liu X
J Cell Mol Med; 2012 Jul; 16(7):1618-28. PubMed ID: 21801305
[TBL] [Abstract][Full Text] [Related]
17. Sirtuins 1 and 2 Are Universal Histone Deacetylases.
Hsu WW; Wu B; Liu WR
ACS Chem Biol; 2016 Mar; 11(3):792-9. PubMed ID: 26820517
[TBL] [Abstract][Full Text] [Related]
18. Frizzled 7 expression is positively regulated by SIRT1 and β-catenin in breast cancer cells.
Simmons GE; Pandey S; Nedeljkovic-Kurepa A; Saxena M; Wang A; Pruitt K
PLoS One; 2014; 9(6):e98861. PubMed ID: 24897117
[TBL] [Abstract][Full Text] [Related]
19. Activation of Kaposi's sarcoma-associated herpesvirus (KSHV) by inhibitors of class III histone deacetylases: identification of sirtuin 1 as a regulator of the KSHV life cycle.
Li Q; He M; Zhou F; Ye F; Gao SJ
J Virol; 2014 Jun; 88(11):6355-67. PubMed ID: 24672028
[TBL] [Abstract][Full Text] [Related]
20. Metformin and tenovin-6 synergistically induces apoptosis through LKB1-independent SIRT1 down-regulation in non-small cell lung cancer cells.
Lee BB; Kim Y; Kim D; Cho EY; Han J; Kim HK; Shim YM; Kim DH
J Cell Mol Med; 2019 Apr; 23(4):2872-2889. PubMed ID: 30710424
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
