259 related articles for article (PubMed ID: 25341566)
41. Hepatitis B virus X protein co-activates pregnane X receptor to induce the cytochrome P450 3A4 enzyme, a potential implication in hepatocarcinogenesis.
Niu Y; Wu Z; Shen Q; Song J; Luo Q; You H; Shi G; Qin W
Dig Liver Dis; 2013 Dec; 45(12):1041-8. PubMed ID: 23891548
[TBL] [Abstract][Full Text] [Related]
42. CYP3A4 Induction in the Liver and Intestine of Pregnane X Receptor/CYP3A-Humanized Mice: Approaches by Mass Spectrometry Imaging and Portal Blood Analysis.
Kobayashi K; Kuze J; Abe S; Takehara S; Minegishi G; Igarashi K; Kitajima S; Kanno J; Yamamoto T; Oshimura M; Kazuki Y
Mol Pharmacol; 2019 Nov; 96(5):600-608. PubMed ID: 31455676
[TBL] [Abstract][Full Text] [Related]
43. Pregnane X receptor-dependent induction of the CYP3A4 gene by o,p'-1,1,1,-trichloro-2,2-bis (p-chlorophenyl)ethane.
Medina-Díaz IM; Arteaga-Illán G; de León MB; Cisneros B; Sierra-Santoyo A; Vega L; Gonzalez FJ; Elizondo G
Drug Metab Dispos; 2007 Jan; 35(1):95-102. PubMed ID: 17035600
[TBL] [Abstract][Full Text] [Related]
44. Glucocorticoid-mediated induction of CYP3A4 is decreased by disruption of a protein: DNA interaction distinct from the pregnane X receptor response element.
El-Sankary W; Bombail V; Gibson GG; Plant N
Drug Metab Dispos; 2002 Sep; 30(9):1029-34. PubMed ID: 12167569
[TBL] [Abstract][Full Text] [Related]
45. Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1.
Wang YM; Lin W; Chai SC; Wu J; Ong SS; Schuetz EG; Chen T
Toxicol Appl Pharmacol; 2013 Oct; 272(1):96-107. PubMed ID: 23707768
[TBL] [Abstract][Full Text] [Related]
46. A food contaminant ochratoxin A suppresses pregnane X receptor (PXR)-mediated CYP3A4 induction in primary cultures of human hepatocytes.
Doricakova A; Vrzal R
Toxicology; 2015 Nov; 337():72-8. PubMed ID: 26341324
[TBL] [Abstract][Full Text] [Related]
47. Photochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor.
Yang J; Yan B
Toxicol Sci; 2007 Jan; 95(1):13-22. PubMed ID: 17003103
[TBL] [Abstract][Full Text] [Related]
48. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
Xu DX; Wei W; Sun MF; Wu CY; Wang JP; Wei LZ; Zhou CF
Free Radic Biol Med; 2004 Jul; 37(1):10-22. PubMed ID: 15183191
[TBL] [Abstract][Full Text] [Related]
49. Relationship between CYP3A29 and pregnane X receptor in landrace pigs: Pig CYP3A29 has a similar mechanism of regulation to human CYP3A4.
He Y; Zhou X; Li X; Jin X; Wang X; Pan X; Bi D
Comp Biochem Physiol C Toxicol Pharmacol; 2018 Dec; 214():9-16. PubMed ID: 30153482
[TBL] [Abstract][Full Text] [Related]
50. Comparison of the hepatic and thyroid gland effects of sodium phenobarbital in wild type and constitutive androstane receptor (CAR) knockout rats and pregnenolone-16α-carbonitrile in wild type and pregnane X receptor (PXR) knockout rats.
Haines C; Chatham LR; Vardy A; Elcombe CR; Foster JR; Lake BG
Toxicology; 2018 May; 400-401():20-27. PubMed ID: 29548889
[TBL] [Abstract][Full Text] [Related]
51. Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines.
Vrzal R; Kubesova K; Pavek P; Dvorak Z
Toxicol Lett; 2010 Mar; 193(2):183-8. PubMed ID: 20080160
[TBL] [Abstract][Full Text] [Related]
52. ncBAF enhances PXR-mediated transcriptional activation in the human and mouse liver.
Kurosawa K; Nakano M; Yokoseki I; Nagaoka M; Takemoto S; Sakai Y; Kobayashi K; Kazuki Y; Fukami T; Nakajima M
Biochem Pharmacol; 2023 Sep; 215():115733. PubMed ID: 37543347
[TBL] [Abstract][Full Text] [Related]
53. Indirubin, a component of Ban-Lan-Gen, activates CYP3A4 gene transcription through the human pregnane X receptor.
Kumagai T; Aratsu Y; Sugawara R; Sasaki T; Miyairi S; Nagata K
Drug Metab Pharmacokinet; 2016 Apr; 31(2):139-45. PubMed ID: 26987505
[TBL] [Abstract][Full Text] [Related]
54. Effect of panaxytriol on cytochrome P450 3A4 via the pregnane X receptor regulatory pathway.
Wu J; Yao N; Hu Q; Liu M; Zhang H; Xiong Y; Hu J; Xia C
Phytother Res; 2019 Apr; 33(4):968-975. PubMed ID: 30653754
[TBL] [Abstract][Full Text] [Related]
55. The traditional Chinese herbal remedy tian xian activates pregnane X receptor and induces CYP3A gene expression in hepatocytes.
Lichti-Kaiser K; Staudinger JL
Drug Metab Dispos; 2008 Aug; 36(8):1538-45. PubMed ID: 18474680
[TBL] [Abstract][Full Text] [Related]
56. Induced CYP3A4 expression in confluent Huh7 hepatoma cells as a result of decreased cell proliferation and subsequent pregnane X receptor activation.
Sivertsson L; Edebert I; Palmertz MP; Ingelman-Sundberg M; Neve EP
Mol Pharmacol; 2013 Mar; 83(3):659-70. PubMed ID: 23264496
[TBL] [Abstract][Full Text] [Related]
57. Reversing effects of ginsenosides on LPS-induced hepatic CYP3A11/3A4 dysfunction through the pregnane X receptor.
Sun HY; Yan YJ; Li YH; Lv L
J Ethnopharmacol; 2019 Jan; 229():246-255. PubMed ID: 30342195
[TBL] [Abstract][Full Text] [Related]
58. Effect of prototypical inducing agents on P-glycoprotein and CYP3A expression in mouse tissues.
Matheny CJ; Ali RY; Yang X; Pollack GM
Drug Metab Dispos; 2004 Sep; 32(9):1008-14. PubMed ID: 15319343
[TBL] [Abstract][Full Text] [Related]
59. Identification of novel pregnane X receptor activators from traditional Chinese medicines.
Yu C; Chai X; Yu L; Chen S; Zeng S
J Ethnopharmacol; 2011 Jun; 136(1):137-43. PubMed ID: 21524698
[TBL] [Abstract][Full Text] [Related]
60. PXR-mediated induction of human CYP3A4 and mouse Cyp3a11 by the glucocorticoid budesonide.
Zimmermann C; van Waterschoot RA; Harmsen S; Maier A; Gutmann H; Schinkel AH
Eur J Pharm Sci; 2009 Mar; 36(4-5):565-71. PubMed ID: 19138736
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]