267 related articles for article (PubMed ID: 25344840)
1. Identification of ligand efficient, fragment-like hits from an HTS library: structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity.
Sarvagalla S; Singh VK; Ke YY; Shiao HY; Lin WH; Hsieh HP; Hsu JT; Coumar MS
J Comput Aided Mol Des; 2015 Jan; 29(1):89-100. PubMed ID: 25344840
[TBL] [Abstract][Full Text] [Related]
2. Ligand efficiency based approach for efficient virtual screening of compound libraries.
Ke YY; Coumar MS; Shiao HY; Wang WC; Chen CW; Song JS; Chen CH; Lin WH; Wu SH; Hsu JT; Chang CM; Hsieh HP
Eur J Med Chem; 2014 Aug; 83():226-35. PubMed ID: 24960626
[TBL] [Abstract][Full Text] [Related]
3. Identification of Novel Aurora Kinase A (AURKA) Inhibitors via Hierarchical Ligand-Based Virtual Screening.
Kong Y; Bender A; Yan A
J Chem Inf Model; 2018 Jan; 58(1):36-47. PubMed ID: 29202231
[TBL] [Abstract][Full Text] [Related]
4. Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design.
Chang CF; Lin WH; Ke YY; Lin YS; Wang WC; Chen CH; Kuo PC; Hsu JTA; Uang BJ; Hsieh HP
Eur J Med Chem; 2016 Nov; 124():186-199. PubMed ID: 27573544
[TBL] [Abstract][Full Text] [Related]
5. Structure-Based Discovery and Bioactivity Evaluation of Novel Aurora-A Kinase Inhibitors as Anticancer Agents via Docking-Based Comparative Intermolecular Contacts Analysis (dbCICA).
Hijjawi MS; Abutayeh RF; Taha MO
Molecules; 2020 Dec; 25(24):. PubMed ID: 33353031
[TBL] [Abstract][Full Text] [Related]
6. Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine Aurora kinase inhibitor.
Shiao HY; Coumar MS; Chang CW; Ke YY; Chi YH; Chu CY; Sun HY; Chen CH; Lin WH; Fung KS; Kuo PC; Huang CT; Chang KY; Lu CT; Hsu JT; Chen CT; Jiaang WT; Chao YS; Hsieh HP
J Med Chem; 2013 Jul; 56(13):5247-60. PubMed ID: 23808327
[TBL] [Abstract][Full Text] [Related]
7. Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening.
Kilchmann F; Marcaida MJ; Kotak S; Schick T; Boss SD; Awale M; Gönczy P; Reymond JL
J Med Chem; 2016 Aug; 59(15):7188-211. PubMed ID: 27391133
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, quantum chemical studies and biological activity evaluation of pyrazole-benzimidazole derivatives as potent Aurora A/B kinase inhibitors.
Zheng Y; Zheng M; Ling X; Liu Y; Xue Y; An L; Gu N; Ji M
Bioorg Med Chem Lett; 2013 Jun; 23(12):3523-30. PubMed ID: 23664099
[TBL] [Abstract][Full Text] [Related]
9. The discovery of aurora kinase inhibitor by multi-docking-based virtual screening.
Kim JT; Jung SH; Kang SY; Ryu CK; Kang NS
Int J Mol Sci; 2014 Nov; 15(11):20403-12. PubMed ID: 25383681
[TBL] [Abstract][Full Text] [Related]
10. Discovery of novel 2,4-disubstituted pyrimidines as Aurora kinase inhibitors.
Xu Y; Hao SY; Zhang XJ; Li WB; Qiao XP; Wang ZX; Chen SW
Bioorg Med Chem Lett; 2020 Feb; 30(3):126885. PubMed ID: 31862411
[TBL] [Abstract][Full Text] [Related]
11. Virtual screening and discovery of novel aurora kinase inhibitors.
Raghu R; Devaraji V; Leena K; Riyaz SD; Rani PB; Kumar BS; Naik PK; Dubey PK; Velmurugan D; Vijayalakshmi M
Curr Top Med Chem; 2014; 14(17):2006-19. PubMed ID: 25262798
[TBL] [Abstract][Full Text] [Related]
12. Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification.
Ke YY; Singh VK; Coumar MS; Hsu YC; Wang WC; Song JS; Chen CH; Lin WH; Wu SH; Hsu JT; Shih C; Hsieh HP
Sci Rep; 2015 Jun; 5():11702. PubMed ID: 26118648
[TBL] [Abstract][Full Text] [Related]
13. Identification of new novel scaffold for Aurora A inhibition by pharmacophore modeling and virtual screening.
Chavan SR; Dash RC; Alam MS; Hirwani RR
Mol Divers; 2014 Nov; 18(4):853-63. PubMed ID: 25112687
[TBL] [Abstract][Full Text] [Related]
14. Identification of 3,5,6-substituted indolin-2-one's inhibitors of Aurora B by development of a luminescent kinase assay.
Zhang L; Yang T; Xie X; Liu G
Bioorg Med Chem Lett; 2015 Aug; 25(15):2937-42. PubMed ID: 26048792
[TBL] [Abstract][Full Text] [Related]
15. Identification, SAR studies, and X-ray co-crystallographic analysis of a novel furanopyrimidine aurora kinase A inhibitor.
Coumar MS; Tsai MT; Chu CY; Uang BJ; Lin WH; Chang CY; Chang TY; Leou JS; Teng CH; Wu JS; Fang MY; Chen CH; Hsu JT; Wu SY; Chao YS; Hsieh HP
ChemMedChem; 2010 Feb; 5(2):255-67. PubMed ID: 20039358
[TBL] [Abstract][Full Text] [Related]
16. General Ser/Thr Kinases Pharmacophore Approach for Selective Kinase Inhibitors Search as Exemplified by Design of Potent and Selective Aurora A Inhibitors.
Vasilevich NI; Aksenova EA; Kazyulkin DN; Afanasyev II
Chem Biol Drug Des; 2016 Jul; 88(1):54-65. PubMed ID: 26825399
[TBL] [Abstract][Full Text] [Related]
17. Aurora isoform selectivity: design and synthesis of imidazo[4,5-b]pyridine derivatives as highly selective inhibitors of Aurora-A kinase in cells.
Bavetsias V; Faisal A; Crumpler S; Brown N; Kosmopoulou M; Joshi A; Atrash B; Pérez-Fuertes Y; Schmitt JA; Boxall KJ; Burke R; Sun C; Avery S; Bush K; Henley A; Raynaud FI; Workman P; Bayliss R; Linardopoulos S; Blagg J
J Med Chem; 2013 Nov; 56(22):9122-35. PubMed ID: 24195668
[TBL] [Abstract][Full Text] [Related]
18. Characterization of a Pyrazolo[4,3-d]pyrimidine Inhibitor of Cyclin-Dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity In Vitro.
Řezníčková E; Weitensteiner S; Havlíček L; Jorda R; Gucký T; Berka K; Bazgier V; Zahler S; Kryštof V; Strnad M
Chem Biol Drug Des; 2015 Dec; 86(6):1528-40. PubMed ID: 26198005
[TBL] [Abstract][Full Text] [Related]
19. Click approach to the discovery of 1,2,3-triazolylsalicylamides as potent Aurora kinase inhibitors.
Song D; Park Y; Yoon J; Aman W; Hah JM; Ryu JS
Bioorg Med Chem; 2014 Sep; 22(17):4855-66. PubMed ID: 25042560
[TBL] [Abstract][Full Text] [Related]
20. Identification of Aurora-A Inhibitors by Ligand and Structure-Based Virtual Screening.
Morshed MN
Mol Inform; 2014 May; 33(5):369-81. PubMed ID: 27485892
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
