BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 25346535)

  • 1. Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.
    Kim DH; Rhee JC; Yeo S; Shen R; Lee SK; Lee JW; Lee S
    Hepatology; 2015 Mar; 61(3):1012-23. PubMed ID: 25346535
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Requirement for MLL3 in p53 regulation of hepatic expression of small heterodimer partner and bile acid homeostasis.
    Kim DH; Kim J; Lee JW
    Mol Endocrinol; 2011 Dec; 25(12):2076-83. PubMed ID: 22034226
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MicroRNA-210 Promotes Bile Acid-Induced Cholestatic Liver Injury by Targeting Mixed-Lineage Leukemia-4 Methyltransferase in Mice.
    Kim YC; Jung H; Seok S; Zhang Y; Ma J; Li T; Kemper B; Kemper JK
    Hepatology; 2020 Jun; 71(6):2118-2134. PubMed ID: 31549733
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.
    Kim DH; Lee J; Lee B; Lee JW
    Mol Endocrinol; 2009 Oct; 23(10):1556-62. PubMed ID: 19556342
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors.
    Lee S; Lee J; Lee SK; Lee JW
    Mol Endocrinol; 2008 Jun; 22(6):1312-9. PubMed ID: 18372346
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis.
    Noshiro M; Usui E; Kawamoto T; Kubo H; Fujimoto K; Furukawa M; Honma S; Makishima M; Honma K; Kato Y
    J Biol Rhythms; 2007 Aug; 22(4):299-311. PubMed ID: 17660447
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.
    Lee J; Saha PK; Yang QH; Lee S; Park JY; Suh Y; Lee SK; Chan L; Roeder RG; Lee JW
    Proc Natl Acad Sci U S A; 2008 Dec; 105(49):19229-34. PubMed ID: 19047629
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Circadian clock function does not require the histone methyltransferase MLL3.
    Baxter M; Poolman T; Cunningham P; Hunter L; Voronkov M; Kitchen GB; Goosey L; Begley N; Kay D; Hespe A; Maidstone R; Loudon ASI; Ray DW
    FASEB J; 2022 Jul; 36(7):e22356. PubMed ID: 35704036
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.
    Lee S; Lee DK; Dou Y; Lee J; Lee B; Kwak E; Kong YY; Lee SK; Roeder RG; Lee JW
    Proc Natl Acad Sci U S A; 2006 Oct; 103(42):15392-7. PubMed ID: 17021013
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.
    Lai B; Lee JE; Jang Y; Wang L; Peng W; Ge K
    Nucleic Acids Res; 2017 Jun; 45(11):6388-6403. PubMed ID: 28398509
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Coordinate Regulation of Cholesterol and Bile Acid Metabolism by the Clock Modifier Nobiletin in Metabolically Challenged Old Mice.
    Nohara K; Nemkov T; D'Alessandro A; Yoo SH; Chen Z
    Int J Mol Sci; 2019 Sep; 20(17):. PubMed ID: 31480535
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Critical Roles of the Histone Methyltransferase MLL4/KMT2D in Murine Hepatic Steatosis Directed by ABL1 and PPARγ2.
    Kim DH; Kim J; Kwon JS; Sandhu J; Tontonoz P; Lee SK; Lee S; Lee JW
    Cell Rep; 2016 Nov; 17(6):1671-1682. PubMed ID: 27806304
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4.
    Lee J; Kim DH; Lee S; Yang QH; Lee DK; Lee SK; Roeder RG; Lee JW
    Proc Natl Acad Sci U S A; 2009 May; 106(21):8513-8. PubMed ID: 19433796
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Retinoid acid-related orphan receptor γ, RORγ, participates in diurnal transcriptional regulation of lipid metabolic genes.
    Takeda Y; Kang HS; Lih FB; Jiang H; Blaner WS; Jetten AM
    Nucleic Acids Res; 2014; 42(16):10448-59. PubMed ID: 25143535
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.
    Hu D; Gao X; Morgan MA; Herz HM; Smith ER; Shilatifard A
    Mol Cell Biol; 2013 Dec; 33(23):4745-54. PubMed ID: 24081332
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha.
    Duez H; van der Veen JN; Duhem C; Pourcet B; Touvier T; Fontaine C; Derudas B; Baugé E; Havinga R; Bloks VW; Wolters H; van der Sluijs FH; Vennström B; Kuipers F; Staels B
    Gastroenterology; 2008 Aug; 135(2):689-98. PubMed ID: 18565334
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism.
    Kang HS; Angers M; Beak JY; Wu X; Gimble JM; Wada T; Xie W; Collins JB; Grissom SF; Jetten AM
    Physiol Genomics; 2007 Oct; 31(2):281-94. PubMed ID: 17666523
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Farnesoid X receptor-induced lysine-specific histone demethylase reduces hepatic bile acid levels and protects the liver against bile acid toxicity.
    Kim YC; Fang S; Byun S; Seok S; Kemper B; Kemper JK
    Hepatology; 2015 Jul; 62(1):220-31. PubMed ID: 25545350
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RORα autoregulates its transcription via MLL4-associated enhancer remodeling in the liver.
    Han YH; Kim HJ; Choi H; Lee S; Lee MO
    Life Sci; 2020 Sep; 256():118007. PubMed ID: 32598934
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone methyltransferase MLL3 contributes to genome-scale circadian transcription.
    Valekunja UK; Edgar RS; Oklejewicz M; van der Horst GT; O'Neill JS; Tamanini F; Turner DJ; Reddy AB
    Proc Natl Acad Sci U S A; 2013 Jan; 110(4):1554-9. PubMed ID: 23297224
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.