234 related articles for article (PubMed ID: 25347186)
1. Mutations at beta N265 in γ-aminobutyric acid type A receptors alter both binding affinity and efficacy of potent anesthetics.
Stewart DS; Pierce DW; Hotta M; Stern AT; Forman SA
PLoS One; 2014; 9(10):e111470. PubMed ID: 25347186
[TBL] [Abstract][Full Text] [Related]
2. Tryptophan and Cysteine Mutations in M1 Helices of α1β3γ2L γ-Aminobutyric Acid Type A Receptors Indicate Distinct Intersubunit Sites for Four Intravenous Anesthetics and One Orphan Site.
Nourmahnad A; Stern AT; Hotta M; Stewart DS; Ziemba AM; Szabo A; Forman SA
Anesthesiology; 2016 Dec; 125(6):1144-1158. PubMed ID: 27753644
[TBL] [Abstract][Full Text] [Related]
3. Cysteine substitutions define etomidate binding and gating linkages in the α-M1 domain of γ-aminobutyric acid type A (GABAA) receptors.
Stewart DS; Hotta M; Li GD; Desai R; Chiara DC; Olsen RW; Forman SA
J Biol Chem; 2013 Oct; 288(42):30373-30386. PubMed ID: 24009076
[TBL] [Abstract][Full Text] [Related]
4. Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor.
Chiara DC; Jayakar SS; Zhou X; Zhang X; Savechenkov PY; Bruzik KS; Miller KW; Cohen JB
J Biol Chem; 2013 Jul; 288(27):19343-57. PubMed ID: 23677991
[TBL] [Abstract][Full Text] [Related]
5. Substituted Cysteine Modification and Protection with
Fantasia RJ; Nourmahnad A; Halpin E; Forman SA
Mol Pharmacol; 2021 Jun; 99(6):426-434. PubMed ID: 33766924
[TBL] [Abstract][Full Text] [Related]
6. A single glycine residue at the entrance to the first membrane-spanning domain of the gamma-aminobutyric acid type A receptor beta(2) subunit affects allosteric sensitivity to GABA and anesthetics.
Carlson BX; Engblom AC; Kristiansen U; Schousboe A; Olsen RW
Mol Pharmacol; 2000 Mar; 57(3):474-84. PubMed ID: 10692487
[TBL] [Abstract][Full Text] [Related]
7. Substituted Cysteine Modification and Protection with n-Alkyl-MTS Reagents Quantifies Steric Changes Induced by a Mutation in Anesthetic Binding Sites on GABA Type A Receptors.
Bhave K; Forman SA
Mol Pharmacol; 2023 Dec; 104(6):266-274. PubMed ID: 37586749
[TBL] [Abstract][Full Text] [Related]
8. A single M1 residue in the beta2 subunit alters channel gating of GABAA receptor in anesthetic modulation and direct activation.
Chang CS; Olcese R; Olsen RW
J Biol Chem; 2003 Oct; 278(44):42821-8. PubMed ID: 12939268
[TBL] [Abstract][Full Text] [Related]
9. Tryptophan mutations at azi-etomidate photo-incorporation sites on alpha1 or beta2 subunits enhance GABAA receptor gating and reduce etomidate modulation.
Stewart D; Desai R; Cheng Q; Liu A; Forman SA
Mol Pharmacol; 2008 Dec; 74(6):1687-95. PubMed ID: 18805938
[TBL] [Abstract][Full Text] [Related]
10. The interaction of general anaesthetics with recombinant GABAA and glycine receptors expressed in Xenopus laevis oocytes: a comparative study.
Pistis M; Belelli D; Peters JA; Lambert JJ
Br J Pharmacol; 1997 Dec; 122(8):1707-19. PubMed ID: 9422818
[TBL] [Abstract][Full Text] [Related]
11. Gamma-amino butyric acid type A receptor mutations at beta2N265 alter etomidate efficacy while preserving basal and agonist-dependent activity.
Desai R; Ruesch D; Forman SA
Anesthesiology; 2009 Oct; 111(4):774-84. PubMed ID: 19741491
[TBL] [Abstract][Full Text] [Related]
12. Functional sites involved in modulation of the GABAA receptor channel by the intravenous anesthetics propofol, etomidate and pentobarbital.
Maldifassi MC; Baur R; Sigel E
Neuropharmacology; 2016 Jun; 105():207-214. PubMed ID: 26767954
[TBL] [Abstract][Full Text] [Related]
13. Two etomidate sites in α1β2γ2 γ-aminobutyric acid type A receptors contribute equally and noncooperatively to modulation of channel gating.
Guitchounts G; Stewart DS; Forman SA
Anesthesiology; 2012 Jun; 116(6):1235-44. PubMed ID: 22531336
[TBL] [Abstract][Full Text] [Related]
14. The effect of a transmembrane amino acid on etomidate sensitivity of an invertebrate GABA receptor.
McGurk KA; Pistis M; Belelli D; Hope AG; Lambert JJ
Br J Pharmacol; 1998 May; 124(1):13-20. PubMed ID: 9630337
[TBL] [Abstract][Full Text] [Related]
15. A Cysteine Substitution Probes β3H267 Interactions with Propofol and Other Potent Anesthetics in α1β3γ2L γ-Aminobutyric Acid Type A Receptors.
Stern AT; Forman SA
Anesthesiology; 2016 Jan; 124(1):89-100. PubMed ID: 26569173
[TBL] [Abstract][Full Text] [Related]
16. Methionine 286 in transmembrane domain 3 of the GABAA receptor beta subunit controls a binding cavity for propofol and other alkylphenol general anesthetics.
Krasowski MD; Nishikawa K; Nikolaeva N; Lin A; Harrison NL
Neuropharmacology; 2001 Dec; 41(8):952-64. PubMed ID: 11747900
[TBL] [Abstract][Full Text] [Related]
17. Etomidate and Etomidate Analog Binding and Positive Modulation of γ-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect.
McGrath M; Yu Z; Jayakar SS; Ma C; Tolia M; Zhou X; Miller KW; Cohen JB; Raines DE
Anesthesiology; 2018 Nov; 129(5):959-969. PubMed ID: 30052529
[TBL] [Abstract][Full Text] [Related]
18. The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid.
Belelli D; Lambert JJ; Peters JA; Wafford K; Whiting PJ
Proc Natl Acad Sci U S A; 1997 Sep; 94(20):11031-6. PubMed ID: 9380754
[TBL] [Abstract][Full Text] [Related]
19. A conserved tyrosine in the beta2 subunit M4 segment is a determinant of gamma-aminobutyric acid type A receptor sensitivity to propofol.
Richardson JE; Garcia PS; O'Toole KK; Derry JM; Bell SV; Jenkins A
Anesthesiology; 2007 Sep; 107(3):412-8. PubMed ID: 17721243
[TBL] [Abstract][Full Text] [Related]
20. State-dependent etomidate occupancy of its allosteric agonist sites measured in a cysteine-substituted GABAA receptor.
Stewart DS; Hotta M; Desai R; Forman SA
Mol Pharmacol; 2013 Jun; 83(6):1200-8. PubMed ID: 23525330
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
