BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 25348018)

  • 21. A comprehensive immunohistochemical and molecular approach to the PI3K/AKT/mTOR (phosphoinositide 3-kinase/v-akt murine thymoma viral oncogene/mammalian target of rapamycin) pathway in bladder urothelial carcinoma.
    Korkolopoulou P; Levidou G; Trigka EA; Prekete N; Karlou M; Thymara I; Sakellariou S; Fragkou P; Isaiadis D; Pavlopoulos P; Patsouris E; Saetta AA
    BJU Int; 2012 Dec; 110(11 Pt C):E1237-48. PubMed ID: 23107319
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Targeting of PI3K/AKT/mTOR pathway to inhibit T cell activation and prevent graft-versus-host disease development.
    Herrero-Sánchez MC; Rodríguez-Serrano C; Almeida J; San Segundo L; Inogés S; Santos-Briz Á; García-Briñón J; Corchete LA; San Miguel JF; Del Cañizo C; Blanco B
    J Hematol Oncol; 2016 Oct; 9(1):113. PubMed ID: 27765055
    [TBL] [Abstract][Full Text] [Related]  

  • 23. PI3K/AKT/mTOR pathway is activated after imatinib secondary resistance in gastrointestinal stromal tumors (GISTs).
    Li J; Dang Y; Gao J; Li Y; Zou J; Shen L
    Med Oncol; 2015 Apr; 32(4):111. PubMed ID: 25757539
    [TBL] [Abstract][Full Text] [Related]  

  • 24. [Recent studies on PI3K/AKT/mTOR signaling pathway in hematopoietic stem cells].
    Zhang YC; Cheng T; Yuan WP
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2013 Feb; 21(1):245-9. PubMed ID: 23484729
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the Eµ-TCL1 mouse model.
    Blunt MD; Carter MJ; Larrayoz M; Smith LD; Aguilar-Hernandez M; Cox KL; Tipton T; Reynolds M; Murphy S; Lemm E; Dias S; Duncombe A; Strefford JC; Johnson PW; Forconi F; Stevenson FK; Packham G; Cragg MS; Steele AJ
    Blood; 2015 Jun; 125(26):4032-41. PubMed ID: 25957390
    [TBL] [Abstract][Full Text] [Related]  

  • 26. HSP70/HSF1 axis, regulated via a PI3K/AKT pathway, is a druggable target in chronic lymphocytic leukemia.
    Frezzato F; Raggi F; Martini V; Severin F; Trimarco V; Visentin A; Scomazzon E; Accordi B; Bresolin S; Piazza F; Facco M; Basso G; Semenzato G; Trentin L
    Int J Cancer; 2019 Dec; 145(11):3089-3100. PubMed ID: 31044428
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice.
    Zanesi N; Aqeilan R; Drusco A; Kaou M; Sevignani C; Costinean S; Bortesi L; La Rocca G; Koldovsky P; Volinia S; Mancini R; Calin G; Scott CP; Pekarsky Y; Croce CM
    Cancer Res; 2006 Jan; 66(2):915-20. PubMed ID: 16424025
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia.
    Ecker V; Stumpf M; Brandmeier L; Neumayer T; Pfeuffer L; Engleitner T; Ringshausen I; Nelson N; Jücker M; Wanninger S; Zenz T; Wendtner C; Manske K; Steiger K; Rad R; Müschen M; Ruland J; Buchner M
    Nat Commun; 2021 Jun; 12(1):3526. PubMed ID: 34112805
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.
    Wlodarski P; Kasprzycka M; Liu X; Marzec M; Robertson ES; Slupianek A; Wasik MA
    Cancer Res; 2005 Sep; 65(17):7800-8. PubMed ID: 16140948
    [TBL] [Abstract][Full Text] [Related]  

  • 30. FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia.
    Seda V; Vojackova E; Ondrisova L; Kostalova L; Sharma S; Loja T; Mladonicka Pavlasova G; Zicha D; Kudlickova Peskova M; Krivanek J; Liskova K; Kren L; Benes V; Musilova Litzmanova K; Borsky M; Oppelt J; Verner J; Pospisilova S; Brychtova Y; Panovska A; Tan Z; Zhang S; Doubek M; Amruz Cerna K; Mayer J; Mraz M
    Blood; 2021 Sep; 138(9):758-772. PubMed ID: 33786575
    [TBL] [Abstract][Full Text] [Related]  

  • 31. TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state.
    Herling M; Patel KA; Khalili J; Schlette E; Kobayashi R; Medeiros LJ; Jones D
    Leukemia; 2006 Feb; 20(2):280-5. PubMed ID: 16341048
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Effects of endoplasmic reticulum stress on autophagy and apoptosis of human leukemia cells via inhibition of the PI3K/AKT/mTOR signaling pathway.
    Li LJ; Chai Y; Guo XJ; Chu SL; Zhang LS
    Mol Med Rep; 2018 Jun; 17(6):7886-7892. PubMed ID: 29620275
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
    Vega F; Medeiros LJ; Leventaki V; Atwell C; Cho-Vega JH; Tian L; Claret FX; Rassidakis GZ
    Cancer Res; 2006 Jul; 66(13):6589-97. PubMed ID: 16818631
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Macrophages confer survival signals via CCR1-dependent translational MCL-1 induction in chronic lymphocytic leukemia.
    van Attekum MHA; Terpstra S; Slinger E; von Lindern M; Moerland PD; Jongejan A; Kater AP; Eldering E
    Oncogene; 2017 Jun; 36(26):3651-3660. PubMed ID: 28192408
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Proliferation, survival and metabolism: the role of PI3K/AKT/mTOR signalling in pluripotency and cell fate determination.
    Yu JS; Cui W
    Development; 2016 Sep; 143(17):3050-60. PubMed ID: 27578176
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy.
    Tsurutani J; West KA; Sayyah J; Gills JJ; Dennis PA
    Cancer Res; 2005 Sep; 65(18):8423-32. PubMed ID: 16166321
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The PI3K pathway: clinical inhibition in chronic lymphocytic leukemia.
    Brown JR
    Semin Oncol; 2016 Apr; 43(2):260-4. PubMed ID: 27040704
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Reduced expression of the tumor suppressor PHLPP1 enhances the antiapoptotic B-cell receptor signal in chronic lymphocytic leukemia B-cells.
    Suljagic M; Laurenti L; Tarnani M; Alam M; Malek SN; Efremov DG
    Leukemia; 2010 Dec; 24(12):2063-71. PubMed ID: 20861921
    [TBL] [Abstract][Full Text] [Related]  

  • 39. B-cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia.
    Schmid VK; Khadour A; Ahmed N; Brandl C; Nitschke L; Rajewsky K; Jumaa H; Hobeika E
    Haematologica; 2022 Aug; 107(8):1796-1814. PubMed ID: 35021605
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Modifying akt signaling in B-cell chronic lymphocytic leukemia cells.
    Hofbauer SW; Piñón JD; Brachtl G; Haginger L; Wang W; Jöhrer K; Tinhofer I; Hartmann TN; Greil R
    Cancer Res; 2010 Sep; 70(18):7336-44. PubMed ID: 20823161
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.