BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 25348602)

  • 1. A new small-molecule Aurora B inhibitor shows antitumor activity in human cancer cell lines.
    Wu Y; Li J; Jiang C; Yang X; Cao L; Yu L
    Mol Biol Rep; 2015 Feb; 42(2):517-24. PubMed ID: 25348602
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A thienopyrimidine derivative induces growth inhibition and apoptosis in human cancer cell lines via inhibiting Aurora B kinase activity.
    Li J; Hu H; Lang Q; Zhang H; Huang Q; Wu Y; Yu L
    Eur J Med Chem; 2013 Jul; 65():151-7. PubMed ID: 23707920
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and aurora kinases.
    Matsuhashi A; Ohno T; Kimura M; Hara A; Saio M; Nagano A; Kawai G; Saitou M; Takigami I; Yamada K; Okano Y; Shimizu K
    Curr Cancer Drug Targets; 2012 Jul; 12(6):625-39. PubMed ID: 22463590
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Optimization and biological evaluation of 2-aminobenzothiazole derivatives as Aurora B kinase inhibitors.
    Lee E; An Y; Kwon J; Kim KI; Jeon R
    Bioorg Med Chem; 2017 Jul; 25(14):3614-3622. PubMed ID: 28529042
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, biological evaluation and molecular modeling study of 2-amino-3,5-disubstituted-pyrazines as Aurora kinases inhibitors.
    Bo YX; Xiang R; Xu Y; Hao SY; Wang XR; Chen SW
    Bioorg Med Chem; 2020 Mar; 28(5):115351. PubMed ID: 32035750
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and NCI-N78 cells.
    Yuan CX; Zhou ZW; Yang YX; He ZX; Zhang X; Wang D; Yang T; Pan SY; Chen XW; Zhou SF
    Drug Des Devel Ther; 2015; 9():1293-318. PubMed ID: 25767376
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aurora kinases as targets in drug-resistant neuroblastoma cells.
    Michaelis M; Selt F; Rothweiler F; Löschmann N; Nüsse B; Dirks WG; Zehner R; Cinatl J
    PLoS One; 2014; 9(9):e108758. PubMed ID: 25268132
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant human glioma cells.
    Premkumar DR; Jane EP; Pollack IF
    Cancer Biol Ther; 2015; 16(2):233-43. PubMed ID: 25482928
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cells.
    D'Alise AM; Amabile G; Iovino M; Di Giorgio FP; Bartiromo M; Sessa F; Villa F; Musacchio A; Cortese R
    Mol Cancer Ther; 2008 May; 7(5):1140-9. PubMed ID: 18483302
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biological characterization of TAK-901, an investigational, novel, multitargeted Aurora B kinase inhibitor.
    Farrell P; Shi L; Matuszkiewicz J; Balakrishna D; Hoshino T; Zhang L; Elliott S; Fabrey R; Lee B; Halkowycz P; Sang B; Ishino S; Nomura T; Teratani M; Ohta Y; Grimshaw C; Paraselli B; Satou T; de Jong R
    Mol Cancer Ther; 2013 Apr; 12(4):460-70. PubMed ID: 23358665
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro and in vivo characterization of a benzofuran derivative, a potential anticancer agent, as a novel Aurora B kinase inhibitor.
    Xie F; Zhu H; Zhang H; Lang Q; Tang L; Huang Q; Yu L
    Eur J Med Chem; 2015 Jan; 89():310-9. PubMed ID: 25462247
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA replication stress in CHK1-depleted tumour cells triggers premature (S-phase) mitosis through inappropriate activation of Aurora kinase B.
    Zuazua-Villar P; Rodriguez R; Gagou ME; Eyers PA; Meuth M
    Cell Death Dis; 2014 May; 5(5):e1253. PubMed ID: 24853431
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective inhibition of Aurora A and B kinases effectively induces cell cycle arrest in t(8;21) acute myeloid leukemia.
    Qi J; Gao X; Zhong X; Zhang N; Wang R; Zhang H; Pan T; Liu X; Yao Y; Wu Q; Niu M; Xu K
    Biomed Pharmacother; 2019 Sep; 117():109113. PubMed ID: 31207577
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Indolin-2-one derivatives as selective Aurora B kinase inhibitors targeting breast cancer.
    Dokla EME; Abdel-Aziz AK; Milik SN; Mahmoud AH; Saadeldin MK; McPhillie MJ; Minucci S; Abouzid KAM
    Bioorg Chem; 2021 Dec; 117():105451. PubMed ID: 34736137
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting Aurora B kinase with Tanshinone IIA suppresses tumor growth and overcomes radioresistance.
    Li M; Liu H; Zhao Q; Han S; Zhou L; Liu W; Li W; Gao F
    Cell Death Dis; 2021 Feb; 12(2):152. PubMed ID: 33542222
    [TBL] [Abstract][Full Text] [Related]  

  • 16. S39, a novel Aurora B kinase inhibitor, shows potent antineoplastic activity in human Hela cervical cancer cell line.
    Li J; Lang Q; Zhang H; Huang Q; Yu L
    Biotechnol Lett; 2013 Jun; 35(6):853-60. PubMed ID: 23443212
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MK-5108, a highly selective Aurora-A kinase inhibitor, shows antitumor activity alone and in combination with docetaxel.
    Shimomura T; Hasako S; Nakatsuru Y; Mita T; Ichikawa K; Kodera T; Sakai T; Nambu T; Miyamoto M; Takahashi I; Miki S; Kawanishi N; Ohkubo M; Kotani H; Iwasawa Y
    Mol Cancer Ther; 2010 Jan; 9(1):157-66. PubMed ID: 20053775
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Treatment of human pre-B acute lymphoblastic leukemia with the Aurora kinase inhibitor PHA-739358 (Danusertib).
    Fei F; Lim M; Schmidhuber S; Moll J; Groffen J; Heisterkamp N
    Mol Cancer; 2012 Jun; 11():42. PubMed ID: 22721004
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Barasertib (AZD1152), a Small Molecule Aurora B Inhibitor, Inhibits the Growth of SCLC Cell Lines In Vitro and In Vivo.
    Helfrich BA; Kim J; Gao D; Chan DC; Zhang Z; Tan AC; Bunn PA
    Mol Cancer Ther; 2016 Oct; 15(10):2314-2322. PubMed ID: 27496133
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.
    Xie H; Lee MH; Zhu F; Reddy K; Peng C; Li Y; Lim DY; Kim DJ; Li X; Kang S; Li H; Ma W; Lubet RA; Ding J; Bode AM; Dong Z
    Cancer Res; 2013 Jan; 73(2):716-24. PubMed ID: 23117881
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.