BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 2535261)

  • 1. On the role of Ca2+ in the toxicity of alkylating and oxidizing quinone imines in isolated hepatocytes.
    Nicotera P; Rundgren M; Porubek DJ; Cotgreave I; Moldéus P; Orrenius S; Nelson SD
    Chem Res Toxicol; 1989; 2(1):46-50. PubMed ID: 2535261
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The toxicity of acetaminophen and N-acetyl-p-benzoquinone imine in isolated hepatocytes is associated with thiol depletion and increased cytosolic Ca2+.
    Moore M; Thor H; Moore G; Nelson S; Moldéus P; Orrenius S
    J Biol Chem; 1985 Oct; 260(24):13035-40. PubMed ID: 2932433
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparative cytotoxic effects of N-acetyl-p-benzoquinone imine and two dimethylated analogues.
    Rundgren M; Porubek DJ; Harvison PJ; Cotgreave IA; Moldéus P; Nelson SD
    Mol Pharmacol; 1988 Oct; 34(4):566-72. PubMed ID: 3173335
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential effects of arylating and oxidizing analogs of N-acetyl-p-benzoquinoneimine on red blood cell membrane proteins.
    Nicotera P; Hinds TR; Nelson SD; Vincenzi FF
    Arch Biochem Biophys; 1990 Nov; 283(1):200-5. PubMed ID: 2146923
    [TBL] [Abstract][Full Text] [Related]  

  • 5. N-acetyl-p-benzoquinone imine-induced protein thiol modification in isolated rat hepatocytes.
    Weis M; Morgenstern R; Cotgreave IA; Nelson SD; Moldéus P
    Biochem Pharmacol; 1992 Apr; 43(7):1493-505. PubMed ID: 1567474
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular mechanism for prevention of N-acetyl-p-benzoquinoneimine cytotoxicity by the permeable thiol drugs diethyldithiocarbamate and dithiothreitol.
    Lauriault VV; O'Brien PJ
    Mol Pharmacol; 1991 Jul; 40(1):125-34. PubMed ID: 1649964
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The mechanism of prevention of paracetamol-induced hepatotoxicity by 3,5-dialkyl substitution. The roles of glutathione depletion and oxidative stress.
    van de Straat R; de Vries J; Debets AJ; Vermeulen NP
    Biochem Pharmacol; 1987 Jul; 36(13):2065-70. PubMed ID: 3606627
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanisms of N-acetyl-p-benzoquinone imine cytotoxicity.
    Albano E; Rundgren M; Harvison PJ; Nelson SD; Moldéus P
    Mol Pharmacol; 1985 Sep; 28(3):306-11. PubMed ID: 4033631
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quinone imine-induced Ca2+ release from isolated rat liver mitochondria.
    Weis M; Moore GA; Cotgreave IA; Nelson SD; Moldeus P
    Chem Biol Interact; 1990; 76(2):227-40. PubMed ID: 2225230
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The killing of cultured hepatocytes by N-acetyl-p-benzoquinone imine (NAPQI) as a model of the cytotoxicity of acetaminophen.
    Harman AW; Kyle ME; Serroni A; Farber JL
    Biochem Pharmacol; 1991 Apr; 41(8):1111-7. PubMed ID: 2009090
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-acetyl-p-benzoquinone imine induces Ca2+ release from mitochondria by stimulating pyridine nucleotide hydrolysis.
    Weis M; Kass GE; Orrenius S; Moldéus P
    J Biol Chem; 1992 Jan; 267(2):804-9. PubMed ID: 1730671
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The metabolism of N-acetyl-3,5-dimethyl-p-benzoquinone imine in isolated hepatocytes involves N-deacetylation.
    Rossi L; McGirr LG; Silva J; O'Brien PJ
    Mol Pharmacol; 1988 Nov; 34(5):674-81. PubMed ID: 3193958
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acetaminophen reactive intermediates target hepatic thioredoxin reductase.
    Jan YH; Heck DE; Dragomir AC; Gardner CR; Laskin DL; Laskin JD
    Chem Res Toxicol; 2014 May; 27(5):882-94. PubMed ID: 24661219
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interactions between N-acetyl-p-benzoquinone imine and fluorescent calcium probes: implications for mechanistic toxicology.
    Riley RJ; Leeder JS; Dosch HM; Spielberg SP
    Anal Biochem; 1990 Dec; 191(2):253-61. PubMed ID: 2085171
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclosporin A protects hepatocytes against prooxidant-induced cell killing. A study on the role of mitochondrial Ca2+ cycling in cytotoxicity.
    Kass GE; Juedes MJ; Orrenius S
    Biochem Pharmacol; 1992 Nov; 44(10):1995-2003. PubMed ID: 1449518
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein and nonprotein cysteinyl thiol modification by N-acetyl-p-benzoquinone imine via a novel ipso adduct.
    Chen W; Shockcor JP; Tonge R; Hunter A; Gartner C; Nelson SD
    Biochemistry; 1999 Jun; 38(25):8159-66. PubMed ID: 10387061
    [TBL] [Abstract][Full Text] [Related]  

  • 17. N-acetyl-p-benzoquinone imine-induced changes in the energy metabolism in hepatocytes.
    Andersson BS; Rundgren M; Nelson SD; Harder S
    Chem Biol Interact; 1990; 75(2):201-11. PubMed ID: 2369786
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytotoxic effects of N-acetyl-p-benzoquinone imine, a common arylating intermediate of paracetamol and N-hydroxyparacetamol.
    Holme JA; Dahlin DC; Nelson SD; Dybing E
    Biochem Pharmacol; 1984 Feb; 33(3):401-6. PubMed ID: 6704159
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity: role of intracellular calcium.
    Kass GE; Wright JM; Nicotera P; Orrenius S
    Arch Biochem Biophys; 1988 Feb; 260(2):789-97. PubMed ID: 2963592
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oxidant-induced changes in the cellular energy homeostasis. A study with 3,5-dimethyl N-acetyl-p-benzoquinone imine and isolated hepatocytes.
    Rundgren M; Harder S; Nelson SD; Andersson BS
    Biochem Pharmacol; 1990 Jul; 40(2):239-43. PubMed ID: 2375766
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.