202 related articles for article (PubMed ID: 25352949)
1. TGF-β induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer.
Singha PK; Pandeswara S; Geng H; Lan R; Venkatachalam MA; Saikumar P
Genes Cancer; 2014 Sep; 5(9-10):320-36. PubMed ID: 25352949
[TBL] [Abstract][Full Text] [Related]
2. Increased Smad3 and reduced Smad2 levels mediate the functional switch of TGF-β from growth suppressor to growth and metastasis promoter through TMEPAI/PMEPA1 in triple negative breast cancer.
Singha PK; Pandeswara S; Geng H; Lan R; Venkatachalam MA; Dobi A; Srivastava S; Saikumar P
Genes Cancer; 2019; 10(5-6):134-149. PubMed ID: 31798766
[TBL] [Abstract][Full Text] [Related]
3. Cooperative induction of transmembrane prostate androgen induced protein TMEPAI/PMEPA1 by transforming growth factor-β and epidermal growth factor signaling.
Azami S; Vo Nguyen TT; Watanabe Y; Kato M
Biochem Biophys Res Commun; 2015 Jan; 456(2):580-5. PubMed ID: 25482449
[TBL] [Abstract][Full Text] [Related]
4. TMEPAI/PMEPA1 enhances tumorigenic activities in lung cancer cells.
Vo Nguyen TT; Watanabe Y; Shiba A; Noguchi M; Itoh S; Kato M
Cancer Sci; 2014 Mar; 105(3):334-41. PubMed ID: 24438557
[TBL] [Abstract][Full Text] [Related]
5. TGF-β-Induced TMEPAI Attenuates the Response of Triple-Negative Breast Cancer Cells to Doxorubicin and Paclitaxel.
Wardhani BW; Puteri MU; Watanabe Y; Louisa M; Setiabudy R; Kato M
J Exp Pharmacol; 2020; 12():17-26. PubMed ID: 32158279
[TBL] [Abstract][Full Text] [Related]
6. TMEPAI/PMEPA1 inhibits Wnt signaling by regulating β-catenin stability and nuclear accumulation in triple negative breast cancer cells.
Amalia R; Abdelaziz M; Puteri MU; Hwang J; Anwar F; Watanabe Y; Kato M
Cell Signal; 2019 Jul; 59():24-33. PubMed ID: 30890370
[TBL] [Abstract][Full Text] [Related]
7. TGF-β-Induced TMEPAI Promotes Epithelial-Mesenchymal Transition in Doxorubicin-Treated Triple-Negative Breast Cancer Cells via SMAD3 and PI3K/AKT Pathway Alteration.
Wardhani BWK; Louisa M; Watanabe Y; Setiabudy R; Kato M
Breast Cancer (Dove Med Press); 2021; 13():529-538. PubMed ID: 34584450
[TBL] [Abstract][Full Text] [Related]
8. Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer.
Singha PK; Yeh IT; Venkatachalam MA; Saikumar P
Cancer Res; 2010 Aug; 70(15):6377-83. PubMed ID: 20610632
[TBL] [Abstract][Full Text] [Related]
9. TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling.
Watanabe Y; Itoh S; Goto T; Ohnishi E; Inamitsu M; Itoh F; Satoh K; Wiercinska E; Yang W; Shi L; Tanaka A; Nakano N; Mommaas AM; Shibuya H; Ten Dijke P; Kato M
Mol Cell; 2010 Jan; 37(1):123-34. PubMed ID: 20129061
[TBL] [Abstract][Full Text] [Related]
10. PMEPA1/TMEPAI Is a Unique Tumorigenic Activator of AKT Promoting Proteasomal Degradation of PHLPP1 in Triple-Negative Breast Cancer Cells.
Haque MA; Abdelaziz M; Puteri MU; Vo Nguyen TT; Kudo K; Watanabe Y; Kato M
Cancers (Basel); 2021 Sep; 13(19):. PubMed ID: 34638419
[TBL] [Abstract][Full Text] [Related]
11. PMEPA1/TMEPAI isoforms function via its PY and Smad-interaction motifs for tumorigenic activities of breast cancer cells.
Puteri MU; Watanabe Y; Wardhani BWK; Amalia R; Abdelaziz M; Kato M
Genes Cells; 2020 Jun; 25(6):375-390. PubMed ID: 32181976
[TBL] [Abstract][Full Text] [Related]
12. TMEPAI inhibits TGF-β signaling by promoting lysosome degradation of TGF-β receptor and contributes to lung cancer development.
Bai X; Jing L; Li Y; Li Y; Luo S; Wang S; Zhou J; Liu Z; Diao A
Cell Signal; 2014 Sep; 26(9):2030-9. PubMed ID: 24933703
[TBL] [Abstract][Full Text] [Related]
13. Analysis of
Sharad S; Sztupinszki ZM; Chen Y; Kuo C; Ravindranath L; Szallasi Z; Petrovics G; Sreenath TL; Dobi A; Rosner IL; Srinivasan A; Srivastava S; Cullen J; Li H
Cancers (Basel); 2019 Dec; 11(12):. PubMed ID: 31842254
[TBL] [Abstract][Full Text] [Related]
14. Cutting the brakes and flooring the gas: how TMEPAI turns TGF-β into a tumor promoter.
Cichon MA; Radisky DC
Genes Cancer; 2014 Sep; 5(9-10):303-5. PubMed ID: 25352947
[TBL] [Abstract][Full Text] [Related]
15. Loss of RAB1B promotes triple-negative breast cancer metastasis by activating TGF-β/SMAD signaling.
Jiang HL; Sun HF; Gao SP; Li LD; Hu X; Wu J; Jin W
Oncotarget; 2015 Jun; 6(18):16352-65. PubMed ID: 25970785
[TBL] [Abstract][Full Text] [Related]
16. TMEPAI regulates EMT in lung cancer cells by modulating the ROS and IRS-1 signaling pathways.
Hu Y; He K; Wang D; Yuan X; Liu Y; Ji H; Song J
Carcinogenesis; 2013 Aug; 34(8):1764-72. PubMed ID: 23615405
[TBL] [Abstract][Full Text] [Related]
17. TMEPAI/PMEPA1 Is a Positive Regulator of Skeletal Muscle Mass.
Hagg A; Kharoud S; Goodchild G; Goodman CA; Chen JL; Thomson RE; Qian H; Gregorevic P; Harrison CA; Walton KL
Front Physiol; 2020; 11():560225. PubMed ID: 33250771
[TBL] [Abstract][Full Text] [Related]
18. PMEPA1/TMEPAI knockout impairs tumour growth and lung metastasis in MDA-MB-231 cells without changing monolayer culture cell growth.
Abdelaziz M; Watanabe Y; Kato M
J Biochem; 2019 May; 165(5):411-414. PubMed ID: 30873542
[TBL] [Abstract][Full Text] [Related]
19. A Smad3-PTEN regulatory loop controls proliferation and apoptotic responses to TGF-β in mouse endometrium.
Eritja N; Felip I; Dosil MA; Vigezzi L; Mirantes C; Yeramian A; Navaridas R; Santacana M; Llobet-Navas D; Yoshimura A; Nomura M; Encinas M; Matias-Guiu X; Dolcet X
Cell Death Differ; 2017 Aug; 24(8):1443-1458. PubMed ID: 28524854
[TBL] [Abstract][Full Text] [Related]
20. TMEPAI family: involvement in regulation of multiple signalling pathways.
Itoh S; Itoh F
J Biochem; 2018 Sep; 164(3):195-204. PubMed ID: 29945215
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]