BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 25362046)

  • 1. Actions of the protein kinase WNK1 on endothelial cells are differentially mediated by its substrate kinases OSR1 and SPAK.
    Dbouk HA; Weil LM; Perera GK; Dellinger MT; Pearson G; Brekken RA; Cobb MH
    Proc Natl Acad Sci U S A; 2014 Nov; 111(45):15999-6004. PubMed ID: 25362046
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting the WNK-SPAK/OSR1 Pathway and Cation-Chloride Cotransporters for the Therapy of Stroke.
    Josiah SS; Meor Azlan NF; Zhang J
    Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33513812
    [TBL] [Abstract][Full Text] [Related]  

  • 3. C. elegans STK39/SPAK ortholog-mediated inhibition of ClC anion channel activity is regulated by WNK-independent ERK kinase signaling.
    Falin RA; Miyazaki H; Strange K
    Am J Physiol Cell Physiol; 2011 Mar; 300(3):C624-35. PubMed ID: 21160027
    [TBL] [Abstract][Full Text] [Related]  

  • 4. WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia.
    Rehman T; Karp PH; Thurman AL; Mather SE; Jain A; Cooney AL; Sinn PL; Pezzulo AA; Duffey ME; Welsh MJ
    Am J Respir Cell Mol Biol; 2022 Oct; 67(4):491-502. PubMed ID: 35849656
    [TBL] [Abstract][Full Text] [Related]  

  • 5. WNK kinase is a vasoactive chloride sensor in endothelial cells.
    Garrud TAC; Bell B; Mata-Daboin A; Peixoto-Neves D; Collier DM; Cordero-Morales JF; Jaggar JH
    Proc Natl Acad Sci U S A; 2024 Apr; 121(15):e2322135121. PubMed ID: 38568964
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
    Zambrowicz BP; Abuin A; Ramirez-Solis R; Richter LJ; Piggott J; BeltrandelRio H; Buxton EC; Edwards J; Finch RA; Friddle CJ; Gupta A; Hansen G; Hu Y; Huang W; Jaing C; Key BW; Kipp P; Kohlhauff B; Ma ZQ; Markesich D; Payne R; Potter DG; Qian N; Shaw J; Schrick J; Shi ZZ; Sparks MJ; Van Sligtenhorst I; Vogel P; Walke W; Xu N; Zhu Q; Person C; Sands AT
    Proc Natl Acad Sci U S A; 2003 Nov; 100(24):14109-14. PubMed ID: 14610273
    [TBL] [Abstract][Full Text] [Related]  

  • 7. K-Cl cotransporters, cell volume homeostasis, and neurological disease.
    Kahle KT; Khanna AR; Alper SL; Adragna NC; Lauf PK; Sun D; Delpire E
    Trends Mol Med; 2015 Aug; 21(8):513-23. PubMed ID: 26142773
    [TBL] [Abstract][Full Text] [Related]  

  • 8. B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice.
    Hayward DA; Vanes L; Wissmann S; Sivapatham S; Hartweger H; Biggs O'May J; de Boer LL; Mitter R; Köchl R; Stein JV; Tybulewicz VLJ
    J Exp Med; 2023 Mar; 220(3):. PubMed ID: 36662229
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Osmosensing by WNK Kinases.
    Akella R; Humphreys JM; Sekulski K; He H; Durbacz M; Chakravarthy S; Liwocha J; Mohammed ZJ; Brautigam CA; Goldsmith EJ
    Mol Biol Cell; 2021 Aug; 32(18):1614-1623. PubMed ID: 33689398
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypertension: the missing WNKs.
    Dbouk HA; Huang CL; Cobb MH
    Am J Physiol Renal Physiol; 2016 Jul; 311(1):F16-27. PubMed ID: 27009339
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crank up the volume: Osmotic stress induces WNK1 phase separation.
    Jung JU; Taylor CA; Cobb MH
    Cell Res; 2023 Apr; 33(4):265-266. PubMed ID: 36550268
    [No Abstract]   [Full Text] [Related]  

  • 12. Generation of WNK1 knockout cell lines by CRISPR/Cas-mediated genome editing.
    Roy A; Goodman JH; Begum G; Donnelly BF; Pittman G; Weinman EJ; Sun D; Subramanya AR
    Am J Physiol Renal Physiol; 2015 Feb; 308(4):F366-76. PubMed ID: 25477473
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of Novel SPAK Inhibitors That Block WNK Kinase Signaling to Cation Chloride Transporters.
    Kikuchi E; Mori T; Zeniya M; Isobe K; Ishigami-Yuasa M; Fujii S; Kagechika H; Ishihara T; Mizushima T; Sasaki S; Sohara E; Rai T; Uchida S
    J Am Soc Nephrol; 2015 Jul; 26(7):1525-36. PubMed ID: 25377078
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of the WNK-SPAK/OSR1 signaling pathway in rodent and human lenses.
    Vorontsova I; Lam L; Delpire E; Lim J; Donaldson P
    Invest Ophthalmol Vis Sci; 2014 Dec; 56(1):310-21. PubMed ID: 25515571
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural and biochemical insights into the activation mechanisms of germinal center kinase OSR1.
    Li C; Feng M; Shi Z; Hao Q; Song X; Wang W; Zhao Y; Jiao S; Zhou Z
    J Biol Chem; 2014 Dec; 289(52):35969-78. PubMed ID: 25389294
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Kelch-Like Protein 2 Mediates Angiotensin II-With No Lysine 3 Signaling in the Regulation of Vascular Tonus.
    Zeniya M; Morimoto N; Takahashi D; Mori Y; Mori T; Ando F; Araki Y; Yoshizaki Y; Inoue Y; Isobe K; Nomura N; Oi K; Nishida H; Sasaki S; Sohara E; Rai T; Uchida S
    J Am Soc Nephrol; 2015 Sep; 26(9):2129-38. PubMed ID: 25556166
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multistep regulation of autophagy by WNK1.
    Gallolu Kankanamalage S; Lee AY; Wichaidit C; Lorente-Rodriguez A; Shah AM; Stippec S; Whitehurst AW; Cobb MH
    Proc Natl Acad Sci U S A; 2016 Dec; 113(50):14342-14347. PubMed ID: 27911840
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Small-molecule WNK inhibition regulates cardiovascular and renal function.
    Yamada K; Park HM; Rigel DF; DiPetrillo K; Whalen EJ; Anisowicz A; Beil M; Berstler J; Brocklehurst CE; Burdick DA; Caplan SL; Capparelli MP; Chen G; Chen W; Dale B; Deng L; Fu F; Hamamatsu N; Harasaki K; Herr T; Hoffmann P; Hu QY; Huang WJ; Idamakanti N; Imase H; Iwaki Y; Jain M; Jeyaseelan J; Kato M; Kaushik VK; Kohls D; Kunjathoor V; LaSala D; Lee J; Liu J; Luo Y; Ma F; Mo R; Mowbray S; Mogi M; Ossola F; Pandey P; Patel SJ; Raghavan S; Salem B; Shanado YH; Trakshel GM; Turner G; Wakai H; Wang C; Weldon S; Wielicki JB; Xie X; Xu L; Yagi YI; Yasoshima K; Yin J; Yowe D; Zhang JH; Zheng G; Monovich L
    Nat Chem Biol; 2016 Nov; 12(11):896-898. PubMed ID: 27595330
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent.
    Boyd-Shiwarski CR; Shiwarski DJ; Roy A; Namboodiri HN; Nkashama LJ; Xie J; McClain KL; Marciszyn A; Kleyman TR; Tan RJ; Stolz DB; Puthenveedu MA; Huang CL; Subramanya AR
    Mol Biol Cell; 2018 Feb; 29(4):499-509. PubMed ID: 29237822
    [TBL] [Abstract][Full Text] [Related]  

  • 20. WNK1 is an unexpected autophagy inhibitor.
    Gallolu Kankanamalage S; Lee AY; Wichaidit C; Lorente-Rodriguez A; Shah AM; Stippec S; Whitehurst AW; Cobb MH
    Autophagy; 2017 May; 13(5):969-970. PubMed ID: 28282258
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.