155 related articles for article (PubMed ID: 2536441)
1. 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent.
Mansuri MM; Starrett JE; Ghazzouli I; Hitchcock MJ; Sterzycki RZ; Brankovan V; Lin TS; August EM; Prusoff WH; Sommadossi JP
J Med Chem; 1989 Feb; 32(2):461-6. PubMed ID: 2536441
[TBL] [Abstract][Full Text] [Related]
2. Comparison of in vitro biological properties and mouse toxicities of three thymidine analogs active against human immunodeficiency virus.
Mansuri MM; Hitchcock MJ; Buroker RA; Bregman CL; Ghazzouli I; Desiderio JV; Starrett JE; Sterzycki RZ; Martin JC
Antimicrob Agents Chemother; 1990 Apr; 34(4):637-41. PubMed ID: 1693057
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and anti-HIV activity of several 2'-fluoro-containing pyrimidine nucleosides.
Sterzycki RZ; Ghazzouli I; Brankovan V; Martin JC; Mansuri MM
J Med Chem; 1990 Aug; 33(8):2150-7. PubMed ID: 2165162
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and anti-HIV evaluation of D4T and D4T 5'-monophosphate prodrugs.
Sergheraert C; Pierlot C; Tartar A; Henin Y; Lemaitre M
J Med Chem; 1993 Apr; 36(7):826-30. PubMed ID: 8385224
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of 1-(3-azido-2,3-dideoxy-beta-D-allofuranosyl)thymine, 1-(2,3-dideoxy-beta-D-allofuranosyl)thymine, and 1-(2,3-dideoxy-beta-D-erythro-hex-2-enofuranosyl)thymine.
Hrebabecký H; Holý A
Carbohydr Res; 1991 Sep; 216():179-86. PubMed ID: 1797378
[TBL] [Abstract][Full Text] [Related]
6. Effects of bone marrow stimulatory cytokines on human immunodeficiency virus replication and the antiviral activity of dideoxynucleosides in cultures of monocyte/macrophages.
Perno CF; Cooney DA; Gao WY; Hao Z; Johns DG; Foli A; Hartman NR; Caliò R; Broder S; Yarchoan R
Blood; 1992 Aug; 80(4):995-1003. PubMed ID: 1379854
[TBL] [Abstract][Full Text] [Related]
7. Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine.
Perno CF; Yarchoan R; Cooney DA; Hartman NR; Webb DS; Hao Z; Mitsuya H; Johns DG; Broder S
J Exp Med; 1989 Mar; 169(3):933-51. PubMed ID: 2538549
[TBL] [Abstract][Full Text] [Related]
8. 5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profile.
Daluge SM; Purifoy DJ; Savina PM; St Clair MH; Parry NR; Dev IK; Novak P; Ayers KM; Reardon JE; Roberts GB
Antimicrob Agents Chemother; 1994 Jul; 38(7):1590-603. PubMed ID: 7526782
[TBL] [Abstract][Full Text] [Related]
9. Metabolism and DNA interaction of 2',3'-didehydro-2',3'-dideoxythymidine in human bone marrow cells.
Zhu Z; Hitchcock MJ; Sommadossi JP
Mol Pharmacol; 1991 Nov; 40(5):838-45. PubMed ID: 1658614
[TBL] [Abstract][Full Text] [Related]
10. In vitro toxicity of 3'-azido-3'-deoxythymidine, carbovir and 2',3'-didehydro-2',3'-dideoxythymidine to human and murine haematopoietic progenitor cells.
Du DL; Volpe DA; Grieshaber CK; Murphy MJ
Br J Haematol; 1992 Apr; 80(4):437-45. PubMed ID: 1316140
[TBL] [Abstract][Full Text] [Related]
11. Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds.
Balzarini J; Herdewijn P; De Clercq E
J Biol Chem; 1989 Apr; 264(11):6127-33. PubMed ID: 2539371
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of 5-homologous AZT and D4T derivatives.
Kjaersgaard U; Pedersen EB; Nielsen C; el-Torgoman AM
Acta Chem Scand (Cph); 1992 Oct; 46(10):1016-20. PubMed ID: 1329897
[TBL] [Abstract][Full Text] [Related]
13. In vitro anti-human immunodeficiency virus activity of 2',3'-dideoxynucleosides and their effect on clonal growth of hemopoietic cells from human bone marrow.
Cinatl J; Cinatl J; Rabenau H; Gümbel H; Doerr HW
Arzneimittelforschung; 1993 May; 43(5):622-5. PubMed ID: 8329011
[TBL] [Abstract][Full Text] [Related]
14. Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog.
Paintsil E; Dutschman GE; Hu R; Grill SP; Lam W; Baba M; Tanaka H; Cheng YC
Antimicrob Agents Chemother; 2007 Nov; 51(11):3870-9. PubMed ID: 17724147
[TBL] [Abstract][Full Text] [Related]
15. Effect of interleukin-1, GM-CSF, erythropoietin, and lithium on the toxicity associated with 3'-azido-3'-deoxythymidine (AZT) in vitro on hematopoietic progenitors (CFU-GM, CFU-MEG, and BFU-E) using murine retrovirus-infected hematopoietic cells.
Gallicchio VS; Hughes NK; Hulette BC; Noblitt L
J Leukoc Biol; 1991 Dec; 50(6):580-6. PubMed ID: 1940611
[TBL] [Abstract][Full Text] [Related]
16. Cellular pharmacology of 2',3'-dideoxy-2',3'-didehydrothymidine, a nucleoside analog active against human immunodeficiency virus.
Ho HT; Hitchcock MJ
Antimicrob Agents Chemother; 1989 Jun; 33(6):844-9. PubMed ID: 2764535
[TBL] [Abstract][Full Text] [Related]
17. Anti-HIV drugs: comparative toxicities in murine fetal liver and bone marrow erythroid progenitor cells.
Gogu SR; Beckman BS; Agrawal KC
Life Sci; 1989; 45(4):iii-vii. PubMed ID: 2761343
[TBL] [Abstract][Full Text] [Related]
18. Synthesis of 4-methylthio analogues of FLT and AZT and their evaluation against HIV.
Abel-Rahman AA; Abdel-Bary HM; Pedersen EB; Nielsen C
Arch Pharm (Weinheim); 1995 Jan; 328(1):67-70. PubMed ID: 7695474
[TBL] [Abstract][Full Text] [Related]
19. Inhibitory effect of azidothymidine, 2'-3'-dideoxyadenosine, and 2'-3'-dideoxycytidine on in vitro growth of hematopoietic progenitor cells from normal persons and from patients with AIDS.
Ganser A; Greher J; Völkers B; Staszewski S; Hoelzer D
Exp Hematol; 1989 May; 17(4):321-5. PubMed ID: 2540017
[TBL] [Abstract][Full Text] [Related]
20. Fluorinated sugar analogues of potential anti-HIV-1 nucleosides.
Huang JT; Chen LC; Wang LB; Kim MH; Warshaw JA; Armstrong D; Zhu QY; Chou TC; Watanabe KA; Matulic-Adamic J
J Med Chem; 1991 May; 34(5):1640-6. PubMed ID: 2033590
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
