These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 2536741)

  • 1. The role of endogenously formed diacylglycerol in the propagation and termination of platelet activation. A biochemical and functional analysis using the novel diacylglycerol kinase inhibitor, R 59 949.
    de Chaffoy de Courcelles D; Roevens P; Van Belle H; Kennis L; Somers Y; De Clerck F
    J Biol Chem; 1989 Feb; 264(6):3274-85. PubMed ID: 2536741
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential effects of the diacylglycerol kinase inhibitor R59022 on thrombin versus collagen-induced human platelet secretion.
    Joseph S; Krishnamurthi S; Kakkar VV
    Biochim Biophys Acta; 1988 Apr; 969(1):9-17. PubMed ID: 2832002
    [TBL] [Abstract][Full Text] [Related]  

  • 3. R 59 022, a diacylglycerol kinase inhibitor. Its effect on diacylglycerol and thrombin-induced C kinase activation in the intact platelet.
    de Chaffoy de Courcelles DC; Roevens P; Van Belle H
    J Biol Chem; 1985 Dec; 260(29):15762-70. PubMed ID: 2999135
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of phospholipase C and protein kinase C has little involvement in ADP-induced primary aggregation of human platelets: effects of diacylglycerols, the diacylglycerols, the diacylglycerol kinase inhibitor R59022, staurosporine and okadaic acid.
    Packham MA; Livne AA; Ruben DH; Rand ML
    Biochem J; 1993 Mar; 290 ( Pt 3)(Pt 3):849-56. PubMed ID: 8384448
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The use of diacylglycerol kinase inhibitors for elucidating the roles of protein kinase C.
    de Chaffoy de Courcelles D
    Adv Second Messenger Phosphoprotein Res; 1990; 24():491-6. PubMed ID: 2169824
    [No Abstract]   [Full Text] [Related]  

  • 6. Selectivity of the diacylglycerol kinase inhibitor 3-[2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl)ethyl]-2, 3-dihydro-2-thioxo-4(1H)quinazolinone (R59949) among diacylglycerol kinase subtypes.
    Jiang Y; Sakane F; Kanoh H; Walsh JP
    Biochem Pharmacol; 2000 Apr; 59(7):763-72. PubMed ID: 10718334
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Delayed accumulation of diacylglycerol in platelets as a mechanism for regulation of onset of aggregation and secretion.
    Werner MH; Hannun YA
    Blood; 1991 Jul; 78(2):435-44. PubMed ID: 2070079
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A diacylglycerol kinase inhibitor, R59022, potentiates secretion by and aggregation of thrombin-stimulated human platelets.
    Nunn DL; Watson SP
    Biochem J; 1987 May; 243(3):809-13. PubMed ID: 2821994
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Control and interrelation of aggregation and secretion; the roles of Ca2+, diacylglycerol and thromboxane with particular reference to ADP stimulation.
    Hallam TJ; Simpson AW; O'Connor N; Rink TJ
    Adv Exp Med Biol; 1985; 192():145-62. PubMed ID: 3010663
    [No Abstract]   [Full Text] [Related]  

  • 10. The diacylglycerol kinase inhibitor, R59949, potentiates secretion but not increased phosphorylation of a 47 kDalton protein in human platelets.
    Rodríguez-Liñares B; Walker T; Watson S
    Biochem Pharmacol; 1991 Mar; 41(5):835-8. PubMed ID: 1847818
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Diacylglycerol overcomes aspirin inhibition of platelets: evidence for a necessary role for diacylglycerol accumulation in platelet activation.
    Werner MH; Senzel L; Bielawska A; Khan W; Hannun YA
    Mol Pharmacol; 1991 Apr; 39(4):547-56. PubMed ID: 2017154
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence for a role for Galphai1 in mediating weak agonist-induced platelet aggregation in human platelets: reduced Galphai1 expression and defective Gi signaling in the platelets of a patient with a chronic bleeding disorder.
    Patel YM; Patel K; Rahman S; Smith MP; Spooner G; Sumathipala R; Mitchell M; Flynn G; Aitken A; Savidge G
    Blood; 2003 Jun; 101(12):4828-35. PubMed ID: 12609843
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tyrosine dephosphorylation, but not phosphorylation, of p130Cas is dependent on integrin alpha IIb beta 3-mediated aggregation in platelets: implication of p130Cas involvement in pathways unrelated to cytoskeletal reorganization.
    Ohmori T; Yatomi Y; Inoue K; Satoh K; Ozaki Y
    Biochemistry; 2000 May; 39(19):5797-807. PubMed ID: 10801330
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Relative importance of diacylglycerol, phosphatidate, lysophosphatidate, inositol trisphosphate and arachidonate metabolism in platelet receptor signalling.
    Lapetina EG; Watson SP
    Nouv Rev Fr Hematol (1978); 1985; 27(4):235-8. PubMed ID: 2997703
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 15-Hydroxyeicosatetraenoic acid-mediated potentiation of thrombin-induced platelet functions occurs via enhanced production of phosphoinositide-derived second messengers--sn-1,2-diacylglycerol and inositol-1,4,5-trisphosphate.
    Setty BN; Werner MH; Hannun YA; Stuart MJ
    Blood; 1992 Dec; 80(11):2765-73. PubMed ID: 1333301
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phorbol esters and oleoyl acetoyl glycerol enhance release of arachidonic acid in platelets stimulated by Ca2+ ionophore A23187.
    Halenda SP; Zavoico GB; Feinstein MB
    J Biol Chem; 1985 Oct; 260(23):12484-91. PubMed ID: 3930496
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of sn-1,2-diacylglycerol second-messenger formation in thrombin-stimulated human platelets. Potentiation by protein kinase C inhibitors.
    Bishop WR; August J; Petrin JM; Pai JK
    Biochem J; 1990 Jul; 269(2):465-73. PubMed ID: 2386487
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 1,2-Dioctanoylglycerol but not 1-oleoyl-2-acetylglycerol inhibits agonist-induced platelet responses. Dependence of effects on extent of 45-kDa protein phosphorylation and agonist type.
    Krishnamurthi S; Joseph S; Kakkar VV
    Eur J Biochem; 1987 Sep; 167(3):585-93. PubMed ID: 3653105
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A role of diacylglycerol kinase in stimulus-secretion coupling of human platelets. Dissociation of serotonin secretion from Ca2+ mobilization.
    Tohmatsu T; Nakashima S; Hattori H; Suganuma A; Nozawa Y
    Thromb Res; 1987 Jul; 47(1):25-35. PubMed ID: 2821648
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of chlorpromazine on phosphatidylinositol turnover following thrombin stimulation of human platelets.
    Wakatabe H; Tsukahara T; Ishigooka J; Miura S
    Biol Psychiatry; 1991 May; 29(10):965-78. PubMed ID: 1905965
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.