BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 25373142)

  • 1. Large transcription units unify copy number variants and common fragile sites arising under replication stress.
    Wilson TE; Arlt MF; Park SH; Rajendran S; Paulsen M; Ljungman M; Glover TW
    Genome Res; 2015 Feb; 25(2):189-200. PubMed ID: 25373142
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impaired Replication Timing Promotes Tissue-Specific Expression of Common Fragile Sites.
    Maccaroni K; Balzano E; Mirimao F; Giunta S; Pelliccia F
    Genes (Basel); 2020 Mar; 11(3):. PubMed ID: 32204553
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Locus-specific transcription silencing at the FHIT gene suppresses replication stress-induced copy number variant formation and associated replication delay.
    Park SH; Bennett-Baker P; Ahmed S; Arlt MF; Ljungman M; Glover TW; Wilson TE
    Nucleic Acids Res; 2021 Jul; 49(13):7507-7524. PubMed ID: 34181717
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genome-wide high-resolution mapping of mitotic DNA synthesis sites and common fragile sites by direct sequencing.
    Ji F; Liao H; Pan S; Ouyang L; Jia F; Fu Z; Zhang F; Geng X; Wang X; Li T; Liu S; Syeda MZ; Chen H; Li W; Chen Z; Shen H; Ying S
    Cell Res; 2020 Nov; 30(11):1009-1023. PubMed ID: 32561861
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insights into common fragile site instability: DNA replication challenges at DNA repeat sequences.
    Irony-Tur Sinai M; Kerem B
    Emerg Top Life Sci; 2023 Dec; 7(3):277-287. PubMed ID: 37876349
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide.
    Brison O; El-Hilali S; Azar D; Koundrioukoff S; Schmidt M; Nähse V; Jaszczyszyn Y; Lachages AM; Dutrillaux B; Thermes C; Debatisse M; Chen CL
    Nat Commun; 2019 Dec; 10(1):5693. PubMed ID: 31836700
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FANCD2 binding identifies conserved fragile sites at large transcribed genes in avian cells.
    Pentzold C; Shah SA; Hansen NR; Le Tallec B; Seguin-Orlando A; Debatisse M; Lisby M; Oestergaard VH
    Nucleic Acids Res; 2018 Feb; 46(3):1280-1294. PubMed ID: 29253234
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stably transfected common fragile site sequences exhibit instability at ectopic sites.
    Ragland RL; Glynn MW; Arlt MF; Glover TW
    Genes Chromosomes Cancer; 2008 Oct; 47(10):860-72. PubMed ID: 18615677
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA replication stress drives fragile site instability.
    Irony-Tur Sinai M; Kerem B
    Mutat Res; 2018 Mar; 808():56-61. PubMed ID: 29074228
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites.
    Twayana S; Bacolla A; Barreto-Galvez A; De-Paula RB; Drosopoulos WC; Kosiyatrakul ST; Bouhassira EE; Tainer JA; Madireddy A; Schildkraut CL
    Proc Natl Acad Sci U S A; 2021 Nov; 118(48):. PubMed ID: 34815340
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 3D genome organization contributes to genome instability at fragile sites.
    Sarni D; Sasaki T; Irony Tur-Sinai M; Miron K; Rivera-Mulia JC; Magnuson B; Ljungman M; Gilbert DM; Kerem B
    Nat Commun; 2020 Jul; 11(1):3613. PubMed ID: 32680994
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fragile sites in cancer: more than meets the eye.
    Glover TW; Wilson TE; Arlt MF
    Nat Rev Cancer; 2017 Jul; 17(8):489-501. PubMed ID: 28740117
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The FRA14B common fragile site maps to a region prone to somatic and germline rearrangements within the large GPHN gene.
    Zheglo D; Brueckner LM; Sepman O; Wecht EM; Kuligina E; Suspitsin E; Imyanitov E; Savelyeva L
    Genes Chromosomes Cancer; 2019 May; 58(5):284-294. PubMed ID: 30411419
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.
    Pladevall-Morera D; Munk S; Ingham A; Garribba L; Albers E; Liu Y; Olsen JV; Lopez-Contreras AJ
    Nucleic Acids Res; 2019 Sep; 47(15):8004-8018. PubMed ID: 31180492
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genomic instability in fragile sites-still adding the pieces.
    Irony-Tur Sinai M; Kerem B
    Genes Chromosomes Cancer; 2019 May; 58(5):295-304. PubMed ID: 30525255
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transcription-replication conflicts as a source of common fragile site instability caused by BMI1-RNF2 deficiency.
    Sanchez A; de Vivo A; Tonzi P; Kim J; Huang TT; Kee Y
    PLoS Genet; 2020 Mar; 16(3):e1008524. PubMed ID: 32142505
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Common fragile sites: mechanisms of instability revisited.
    Debatisse M; Le Tallec B; Letessier A; Dutrillaux B; Brison O
    Trends Genet; 2012 Jan; 28(1):22-32. PubMed ID: 22094264
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Common fragile sites are conserved features of human and mouse chromosomes and relate to large active genes.
    Helmrich A; Stout-Weider K; Hermann K; Schrock E; Heiden T
    Genome Res; 2006 Oct; 16(10):1222-30. PubMed ID: 16954539
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Detection and Analysis of Chromosome Fragile Sites.
    Bjerregaard VA; Özer Ö; Hickson ID; Liu Y
    Methods Mol Biol; 2018; 1672():471-482. PubMed ID: 29043642
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Common fragile sites are characterized by histone hypoacetylation.
    Jiang Y; Lucas I; Young DJ; Davis EM; Karrison T; Rest JS; Le Beau MM
    Hum Mol Genet; 2009 Dec; 18(23):4501-12. PubMed ID: 19717471
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.