These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

458 related articles for article (PubMed ID: 25378155)

  • 1. Impaired action potential initiation in GABAergic interneurons causes hyperexcitable networks in an epileptic mouse model carrying a human Na(V)1.1 mutation.
    Hedrich UB; Liautard C; Kirschenbaum D; Pofahl M; Lavigne J; Liu Y; Theiss S; Slotta J; Escayg A; Dihné M; Beck H; Mantegazza M; Lerche H
    J Neurosci; 2014 Nov; 34(45):14874-89. PubMed ID: 25378155
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modeling NaV1.1/SCN1A sodium channel mutations in a microcircuit with realistic ion concentration dynamics suggests differential GABAergic mechanisms leading to hyperexcitability in epilepsy and hemiplegic migraine.
    Lemaire L; Desroches M; Krupa M; Pizzamiglio L; Scalmani P; Mantegazza M
    PLoS Comput Biol; 2021 Jul; 17(7):e1009239. PubMed ID: 34314446
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Transient Developmental Window of Fast-Spiking Interneuron Dysfunction in a Mouse Model of Dravet Syndrome.
    Favero M; Sotuyo NP; Lopez E; Kearney JA; Goldberg EM
    J Neurosci; 2018 Sep; 38(36):7912-7927. PubMed ID: 30104343
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impairment of Sharp-Wave Ripples in a Murine Model of Dravet Syndrome.
    Cheah CS; Lundstrom BN; Catterall WA; Oakley JC
    J Neurosci; 2019 Nov; 39(46):9251-9260. PubMed ID: 31537705
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aberrant Sodium Channel Currents and Hyperexcitability of Medial Entorhinal Cortex Neurons in a Mouse Model of
    Ottolini M; Barker BS; Gaykema RP; Meisler MH; Patel MK
    J Neurosci; 2017 Aug; 37(32):7643-7655. PubMed ID: 28676574
    [No Abstract]   [Full Text] [Related]  

  • 6. Dravet Syndrome: A Developmental and Epileptic Encephalopathy.
    Lopez-Santiago L; Isom LL
    Epilepsy Curr; 2019 Jan; 19(1):51-53. PubMed ID: 30838929
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CRISPR/Cas9 facilitates investigation of neural circuit disease using human iPSCs: mechanism of epilepsy caused by an SCN1A loss-of-function mutation.
    Liu J; Gao C; Chen W; Ma W; Li X; Shi Y; Zhang H; Zhang L; Long Y; Xu H; Guo X; Deng S; Yan X; Yu D; Pan G; Chen Y; Lai L; Liao W; Li Z
    Transl Psychiatry; 2016 Jan; 6(1):e703. PubMed ID: 26731440
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Knock-in model of Dravet syndrome reveals a constitutive and conditional reduction in sodium current.
    Schutte RJ; Schutte SS; Algara J; Barragan EV; Gilligan J; Staber C; Savva YA; Smith MA; Reenan R; O'Dowd DK
    J Neurophysiol; 2014 Aug; 112(4):903-12. PubMed ID: 24805083
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Preictal dysfunctions of inhibitory interneurons paradoxically lead to their rebound hyperactivity and to low-voltage-fast onset seizures in Dravet syndrome.
    Capitano F; Kuchenbuch M; Lavigne J; Chaptoukaev H; Zuluaga MA; Lorenzi M; Nabbout R; Mantegazza M
    Proc Natl Acad Sci U S A; 2024 Jun; 121(23):e2316364121. PubMed ID: 38809712
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Altered function of the SCN1A voltage-gated sodium channel leads to gamma-aminobutyric acid-ergic (GABAergic) interneuron abnormalities.
    Martin MS; Dutt K; Papale LA; Dubé CM; Dutton SB; de Haan G; Shankar A; Tufik S; Meisler MH; Baram TZ; Goldin AL; Escayg A
    J Biol Chem; 2010 Mar; 285(13):9823-9834. PubMed ID: 20100831
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A small molecule activator of Na
    Frederiksen K; Lu D; Yang J; Jensen HS; Bastlund JF; Larsen PH; Liu H; Crestey F; Dekermendjian K; Badolo L; Laursen M; Hougaard C; Yang C; Svenstrup N; Grunnet M
    Eur J Neurosci; 2017 Aug; 46(3):1887-1896. PubMed ID: 28635024
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome.
    Rubinstein M; Westenbroek RE; Yu FH; Jones CJ; Scheuer T; Catterall WA
    Neurobiol Dis; 2015 Jan; 73():106-17. PubMed ID: 25281316
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dissecting the phenotypes of Dravet syndrome by gene deletion.
    Rubinstein M; Han S; Tai C; Westenbroek RE; Hunker A; Scheuer T; Catterall WA
    Brain; 2015 Aug; 138(Pt 8):2219-33. PubMed ID: 26017580
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.
    Ogiwara I; Miyamoto H; Morita N; Atapour N; Mazaki E; Inoue I; Takeuchi T; Itohara S; Yanagawa Y; Obata K; Furuichi T; Hensch TK; Yamakawa K
    J Neurosci; 2007 May; 27(22):5903-14. PubMed ID: 17537961
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome.
    Kalume F; Oakley JC; Westenbroek RE; Gile J; de la Iglesia HO; Scheuer T; Catterall WA
    Neurobiol Dis; 2015 May; 77():141-54. PubMed ID: 25766678
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Unaltered Network Activity and Interneuronal Firing During Spontaneous Cortical Dynamics In Vivo in a Mouse Model of Severe Myoclonic Epilepsy of Infancy.
    De Stasi AM; Farisello P; Marcon I; Cavallari S; Forli A; Vecchia D; Losi G; Mantegazza M; Panzeri S; Carmignoto G; Bacci A; Fellin T
    Cereb Cortex; 2016 Apr; 26(4):1778-94. PubMed ID: 26819275
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome.
    Tai C; Abe Y; Westenbroek RE; Scheuer T; Catterall WA
    Proc Natl Acad Sci U S A; 2014 Jul; 111(30):E3139-48. PubMed ID: 25024183
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development.
    Tsai MS; Lee ML; Chang CY; Fan HH; Yu IS; Chen YT; You JY; Chen CY; Chang FC; Hsiao JH; Khorkova O; Liou HH; Yanagawa Y; Lee LJ; Lin SW
    Neurobiol Dis; 2015 May; 77():35-48. PubMed ID: 25725421
    [TBL] [Abstract][Full Text] [Related]  

  • 19. dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice.
    Colasante G; Lignani G; Brusco S; Di Berardino C; Carpenter J; Giannelli S; Valassina N; Bido S; Ricci R; Castoldi V; Marenna S; Church T; Massimino L; Morabito G; Benfenati F; Schorge S; Leocani L; Kullmann DM; Broccoli V
    Mol Ther; 2020 Jan; 28(1):235-253. PubMed ID: 31607539
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A selective Na
    Chow CY; Chin YKY; Ma L; Undheim EAB; Herzig V; King GF
    Biochem Pharmacol; 2020 Nov; 181():113991. PubMed ID: 32335140
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.