These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 25382819)

  • 1. ProKinO: a unified resource for mining the cancer kinome.
    McSkimming DI; Dastgheib S; Talevich E; Narayanan A; Katiyar S; Taylor SS; Kochut K; Kannan N
    Hum Mutat; 2015 Feb; 36(2):175-86. PubMed ID: 25382819
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ProKinO: an ontology for integrative analysis of protein kinases in cancer.
    Gosal G; Kochut KJ; Kannan N
    PLoS One; 2011; 6(12):e28782. PubMed ID: 22194913
    [TBL] [Abstract][Full Text] [Related]  

  • 3. INTEGRATING GENETIC AND STRUCTURAL DATA ON HUMAN PROTEIN KINOME IN NETWORK-BASED MODELING OF KINASE SENSITIVITIES AND RESISTANCE TO TARGETED AND PERSONALIZED ANTICANCER DRUGS.
    Verkhivker GM
    Pac Symp Biocomput; 2016; 21():45-56. PubMed ID: 26776172
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computational and Experimental Characterization of Patient Derived Mutations Reveal an Unusual Mode of Regulatory Spine Assembly and Drug Sensitivity in EGFR Kinase.
    Ruan Z; Katiyar S; Kannan N
    Biochemistry; 2017 Jan; 56(1):22-32. PubMed ID: 27936599
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The resistance tetrad: amino acid hotspots for kinome-wide exploitation of drug-resistant protein kinase alleles.
    Bailey FP; Andreev VI; Eyers PA
    Methods Enzymol; 2014; 548():117-46. PubMed ID: 25399644
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The ErbB/HER family of protein-tyrosine kinases and cancer.
    Roskoski R
    Pharmacol Res; 2014 Jan; 79():34-74. PubMed ID: 24269963
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Integrative annotation and knowledge discovery of kinase post-translational modifications and cancer-associated mutations through federated protein ontologies and resources.
    Huang LC; Ross KE; Baffi TR; Drabkin H; Kochut KJ; Ruan Z; D'Eustachio P; McSkimming D; Arighi C; Chen C; Natale DA; Smith C; Gaudet P; Newton AC; Wu C; Kannan N
    Sci Rep; 2018 Apr; 8(1):6518. PubMed ID: 29695735
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The molecular basis of targeting protein kinases in cancer therapeutics.
    Tsai CJ; Nussinov R
    Semin Cancer Biol; 2013 Aug; 23(4):235-42. PubMed ID: 23651790
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The evolution of protein kinase inhibitors from antagonists to agonists of cellular signaling.
    Dar AC; Shokat KM
    Annu Rev Biochem; 2011; 80():769-95. PubMed ID: 21548788
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Emerging roles of the αC-β4 loop in protein kinase structure, function, evolution, and disease.
    Yeung W; Ruan Z; Kannan N
    IUBMB Life; 2020 Jun; 72(6):1189-1202. PubMed ID: 32101380
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Impact of common epidermal growth factor receptor and HER2 variants on receptor activity and inhibition by lapatinib.
    Gilmer TM; Cable L; Alligood K; Rusnak D; Spehar G; Gallagher KT; Woldu E; Carter HL; Truesdale AT; Shewchuk L; Wood ER
    Cancer Res; 2008 Jan; 68(2):571-9. PubMed ID: 18199554
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sequence and structure signatures of cancer mutation hotspots in protein kinases.
    Dixit A; Yi L; Gowthaman R; Torkamani A; Schork NJ; Verkhivker GM
    PLoS One; 2009 Oct; 4(10):e7485. PubMed ID: 19834613
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A general framework for inhibitor resistance in protein kinases.
    Balzano D; Santaguida S; Musacchio A; Villa F
    Chem Biol; 2011 Aug; 18(8):966-75. PubMed ID: 21867912
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Combined epidermal growth factor receptor targeting with the tyrosine kinase inhibitor gefitinib (ZD1839) and the monoclonal antibody cetuximab (IMC-C225): superiority over single-agent receptor targeting.
    Matar P; Rojo F; Cassia R; Moreno-Bueno G; Di Cosimo S; Tabernero J; Guzmán M; Rodriguez S; Arribas J; Palacios J; Baselga J
    Clin Cancer Res; 2004 Oct; 10(19):6487-501. PubMed ID: 15475436
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Homology models of the mutated EGFR and their response towards quinazoline analogues.
    Kotra S; Madala KK; Jamil K
    J Mol Graph Model; 2008 Oct; 27(3):244-54. PubMed ID: 18585943
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Clinical Kinase Index: A Method to Prioritize Understudied Kinases as Drug Targets for the Treatment of Cancer.
    Essegian D; Khurana R; Stathias V; Schürer SC
    Cell Rep Med; 2020 Oct; 1(7):100128. PubMed ID: 33205077
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An alternative inhibitor overcomes resistance caused by a mutation of the epidermal growth factor receptor.
    Kobayashi S; Ji H; Yuza Y; Meyerson M; Wong KK; Tenen DG; Halmos B
    Cancer Res; 2005 Aug; 65(16):7096-101. PubMed ID: 16103058
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting cathepsin S induces tumor cell autophagy via the EGFR-ERK signaling pathway.
    Chen KL; Chang WS; Cheung CH; Lin CC; Huang CC; Yang YN; Kuo CP; Kuo CC; Chang YH; Liu KJ; Wu CM; Chang JY
    Cancer Lett; 2012 Apr; 317(1):89-98. PubMed ID: 22101325
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Defining the landscape of ATP-competitive inhibitor resistance residues in protein kinases.
    Persky NS; Hernandez D; Do Carmo M; Brenan L; Cohen O; Kitajima S; Nayar U; Walker A; Pantel S; Lee Y; Cordova J; Sathappa M; Zhu C; Hayes TK; Ram P; Pancholi P; Mikkelsen TS; Barbie DA; Yang X; Haq R; Piccioni F; Root DE; Johannessen CM
    Nat Struct Mol Biol; 2020 Jan; 27(1):92-104. PubMed ID: 31925410
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Landscape of Atypical and Eukaryotic Protein Kinases.
    Kanev GK; de Graaf C; de Esch IJP; Leurs R; Würdinger T; Westerman BA; Kooistra AJ
    Trends Pharmacol Sci; 2019 Nov; 40(11):818-832. PubMed ID: 31677919
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.