Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

952 related articles for article (PubMed ID: 25384422)

  • 1. Activation of the Wnt/β-catenin pathway represses the transcription of the β-amyloid precursor protein cleaving enzyme (BACE1) via binding of T-cell factor-4 to BACE1 promoter.
    Parr C; Mirzaei N; Christian M; Sastre M
    FASEB J; 2015 Feb; 29(2):623-35. PubMed ID: 25384422
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phospholipase D1 drives a positive feedback loop to reinforce the Wnt/beta-catenin/TCF signaling axis.
    Kang DW; Lee SH; Yoon JW; Park WS; Choi KY; Min do S
    Cancer Res; 2010 May; 70(10):4233-42. PubMed ID: 20442281
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IFN-gamma-induced BACE1 expression is mediated by activation of JAK2 and ERK1/2 signaling pathways and direct binding of STAT1 to BACE1 promoter in astrocytes.
    Cho HJ; Kim SK; Jin SM; Hwang EM; Kim YS; Huh K; Mook-Jung I
    Glia; 2007 Feb; 55(3):253-62. PubMed ID: 17091494
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differentiation-inducing factor-1 alters canonical Wnt signaling and suppresses alkaline phosphatase expression in osteoblast-like cell lines.
    Matsuzaki E; Takahashi-Yanaga F; Miwa Y; Hirata M; Watanabe Y; Sato N; Morimoto S; Hirofuji T; Maeda K; Sasaguri T
    J Bone Miner Res; 2006 Aug; 21(8):1307-16. PubMed ID: 16869729
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Wnt3a stimulates Mepe, matrix extracellular phosphoglycoprotein, expression directly by the activation of the canonical Wnt signaling pathway and indirectly through the stimulation of autocrine Bmp-2 expression.
    Cho YD; Kim WJ; Yoon WJ; Woo KM; Baek JH; Lee G; Kim GS; Ryoo HM
    J Cell Physiol; 2012 Jun; 227(6):2287-96. PubMed ID: 22213482
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The EWS/FLI1 oncogenic protein inhibits expression of the Wnt inhibitor DICKKOPF-1 gene and antagonizes beta-catenin/TCF-mediated transcription.
    Navarro D; Agra N; Pestaña A; Alonso J; González-Sancho JM
    Carcinogenesis; 2010 Mar; 31(3):394-401. PubMed ID: 20019092
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer.
    González-Sancho JM; Aguilera O; García JM; Pendás-Franco N; Peña C; Cal S; García de Herreros A; Bonilla F; Muñoz A
    Oncogene; 2005 Feb; 24(6):1098-103. PubMed ID: 15592505
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells.
    Chen LM; Lin ZY; Zhu YG; Lin N; Zhang J; Pan XD; Chen XC
    Eur J Pharmacol; 2012 Jan; 675(1-3):15-21. PubMed ID: 22166376
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling.
    Cho HJ; Jin SM; Youn HD; Huh K; Mook-Jung I
    Aging Cell; 2008 Mar; 7(2):137-47. PubMed ID: 18081741
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of the canonical WNT signaling pathway promotes ovarian surface epithelial proliferation without inducing β-catenin/Tcf-mediated reporter expression.
    Usongo M; Li X; Farookhi R
    Dev Dyn; 2013 Mar; 242(3):291-300. PubMed ID: 23239518
    [TBL] [Abstract][Full Text] [Related]  

  • 12. N-glycosylation gene DPAGT1 is a target of the Wnt/beta-catenin signaling pathway.
    Sengupta PK; Bouchie MP; Kukuruzinska MA
    J Biol Chem; 2010 Oct; 285(41):31164-73. PubMed ID: 20693288
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of beta-catenin signalling increases StarD7 gene expression in JEG-3 cells.
    Rena V; Angeletti S; Panzetta-Dutari G; Genti-Raimondi S
    Placenta; 2009 Oct; 30(10):876-83. PubMed ID: 19679347
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease.
    Chen CH; Zhou W; Liu S; Deng Y; Cai F; Tone M; Tone Y; Tong Y; Song W
    Int J Neuropsychopharmacol; 2012 Feb; 15(1):77-90. PubMed ID: 21329555
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distinct transcriptional regulation and function of the human BACE2 and BACE1 genes.
    Sun X; Wang Y; Qing H; Christensen MA; Liu Y; Zhou W; Tong Y; Xiao C; Huang Y; Zhang S; Liu X; Song W
    FASEB J; 2005 May; 19(7):739-49. PubMed ID: 15857888
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease.
    Rossner S; Sastre M; Bourne K; Lichtenthaler SF
    Prog Neurobiol; 2006 Jun; 79(2):95-111. PubMed ID: 16904810
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ITF2 prevents activation of the β-catenin-TCF4 complex in colon cancer cells and levels decrease with tumor progression.
    Shin HW; Choi H; So D; Kim YI; Cho K; Chung HJ; Lee KH; Chun YS; Cho CH; Kang GH; Kim WH; Park JW
    Gastroenterology; 2014 Aug; 147(2):430-442.e8. PubMed ID: 24846398
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: induction of promoter demethylation and histone modification causing inhibition of Wnt signaling.
    Shin H; Kim JH; Lee YS; Lee YC
    Int J Oncol; 2012 May; 40(5):1533-42. PubMed ID: 22246241
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells.
    Panmanee J; Nopparat C; Chavanich N; Shukla M; Mukda S; Song W; Vincent B; Govitrapong P
    J Pineal Res; 2015 Oct; 59(3):308-20. PubMed ID: 26123100
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bach1 Represses Wnt/β-Catenin Signaling and Angiogenesis.
    Jiang L; Yin M; Wei X; Liu J; Wang X; Niu C; Kang X; Xu J; Zhou Z; Sun S; Wang X; Zheng X; Duan S; Yao K; Qian R; Sun N; Chen A; Wang R; Zhang J; Chen S; Meng D
    Circ Res; 2015 Jul; 117(4):364-375. PubMed ID: 26123998
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 48.