439 related articles for article (PubMed ID: 25386663)
1. The small-molecule inhibitor selectivity between IKKα and IKKβ kinases in NF-κB signaling pathway.
Tian F; Zhou P; Kang W; Luo L; Fan X; Yan J; Liang H
J Recept Signal Transduct Res; 2015; 35(4):307-18. PubMed ID: 25386663
[TBL] [Abstract][Full Text] [Related]
2. Regulation and function of IKK and IKK-related kinases.
Häcker H; Karin M
Sci STKE; 2006 Oct; 2006(357):re13. PubMed ID: 17047224
[TBL] [Abstract][Full Text] [Related]
3. NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation.
Solt LA; Madge LA; May MJ
J Biol Chem; 2009 Oct; 284(40):27596-608. PubMed ID: 19666475
[TBL] [Abstract][Full Text] [Related]
4. IKKα plays a major role in canonical NF-κB signalling in colorectal cells.
Prescott JA; Balmanno K; Mitchell JP; Okkenhaug H; Cook SJ
Biochem J; 2022 Feb; 479(3):305-325. PubMed ID: 35029639
[TBL] [Abstract][Full Text] [Related]
5. Novel non-peptide small molecules preventing IKKβ/NEMO association inhibit NF-κB activation in LPS-stimulated J774 macrophages.
De Falco F; Di Giovanni C; Cerchia C; De Stefano D; Capuozzo A; Irace C; Iuvone T; Santamaria R; Carnuccio R; Lavecchia A
Biochem Pharmacol; 2016 Mar; 104():83-94. PubMed ID: 26776306
[TBL] [Abstract][Full Text] [Related]
6. Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen.
Lam LT; Davis RE; Ngo VN; Lenz G; Wright G; Xu W; Zhao H; Yu X; Dang L; Staudt LM
Proc Natl Acad Sci U S A; 2008 Dec; 105(52):20798-803. PubMed ID: 19104039
[TBL] [Abstract][Full Text] [Related]
7. The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation.
Zandi E; Rothwarf DM; Delhase M; Hayakawa M; Karin M
Cell; 1997 Oct; 91(2):243-52. PubMed ID: 9346241
[TBL] [Abstract][Full Text] [Related]
8. Phosphorylation of serine 68 in the IkappaB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-alpha-induced NF-kappaB activity.
Palkowitsch L; Leidner J; Ghosh S; Marienfeld RB
J Biol Chem; 2008 Jan; 283(1):76-86. PubMed ID: 17977820
[TBL] [Abstract][Full Text] [Related]
9. Combination of pharmacophore model development and binding mode analyses: identification of ligand features essential for IκB kinase-beta (IKKβ) inhibitors and virtual screening based on it.
Sun HP; Zhu J; Chen FH; Zhang SL; Zhang Y; You QD
Eur J Med Chem; 2011 Sep; 46(9):3942-52. PubMed ID: 21708416
[TBL] [Abstract][Full Text] [Related]
10. Pentacyclic Triterpenoids Inhibit IKKβ Mediated Activation of NF-κB Pathway: In Silico and In Vitro Evidences.
Patil KR; Mohapatra P; Patel HM; Goyal SN; Ojha S; Kundu CN; Patil CR
PLoS One; 2015; 10(5):e0125709. PubMed ID: 25938234
[TBL] [Abstract][Full Text] [Related]
11. The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis.
Li ZW; Chu W; Hu Y; Delhase M; Deerinck T; Ellisman M; Johnson R; Karin M
J Exp Med; 1999 Jun; 189(11):1839-45. PubMed ID: 10359587
[TBL] [Abstract][Full Text] [Related]
12. Dimer of arfaptin 2 regulates NF-κB signaling by interacting with IKKβ/NEMO and inhibiting IKKβ kinase activity.
You DJ; Park CR; Furlong M; Koo O; Lee C; Ahn C; Seong JY; Hwang JI
Cell Signal; 2015 Nov; 27(11):2173-81. PubMed ID: 26296658
[TBL] [Abstract][Full Text] [Related]
13. IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway.
Adli M; Merkhofer E; Cogswell P; Baldwin AS
PLoS One; 2010 Feb; 5(2):e9428. PubMed ID: 20195534
[TBL] [Abstract][Full Text] [Related]
14. Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer.
Nottingham LK; Yan CH; Yang X; Si H; Coupar J; Bian Y; Cheng TF; Allen C; Arun P; Gius D; Dang L; Van Waes C; Chen Z
Oncogene; 2014 Feb; 33(9):1135-47. PubMed ID: 23455325
[TBL] [Abstract][Full Text] [Related]
15. Disulfide-mediated stabilization of the IκB kinase binding domain of NF-κB essential modulator (NEMO).
Zhou L; Yeo AT; Ballarano C; Weber U; Allen KN; Gilmore TD; Whitty A
Biochemistry; 2014 Dec; 53(50):7929-44. PubMed ID: 25400026
[TBL] [Abstract][Full Text] [Related]
16. Structure and dynamics of the kinase IKK-β--A key regulator of the NF-kappa B transcription factor.
Kalia M; Kukol A
J Struct Biol; 2011 Nov; 176(2):133-42. PubMed ID: 21820058
[TBL] [Abstract][Full Text] [Related]
17. Tautomycetin suppresses the TNFalpha/NF-kappaB pathway via inhibition of IKK activation.
Mitsuhashi S; Shima H; Li Y; Tanuma N; Okamoto T; Kikuchi K; Ubukata M
Int J Oncol; 2008 Nov; 33(5):1027-35. PubMed ID: 18949366
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of the NEMO/IKKβ association complex formation, a novel mechanism associated with the NF-κB activation suppression by Withania somnifera's key metabolite withaferin A.
Grover A; Shandilya A; Punetha A; Bisaria VS; Sundar D
BMC Genomics; 2010 Dec; 11 Suppl 4(Suppl 4):S25. PubMed ID: 21143809
[TBL] [Abstract][Full Text] [Related]
19. Inhibitor of NF-kappa B kinases alpha and beta are both essential for high mobility group box 1-mediated chemotaxis [corrected].
Penzo M; Molteni R; Suda T; Samaniego S; Raucci A; Habiel DM; Miller F; Jiang HP; Li J; Pardi R; Palumbo R; Olivotto E; Kew RR; Bianchi ME; Marcu KB
J Immunol; 2010 Apr; 184(8):4497-509. PubMed ID: 20231695
[TBL] [Abstract][Full Text] [Related]
20. Inhibitory Kappa B Kinase α (IKKα) Inhibitors That Recapitulate Their Selectivity in Cells against Isoform-Related Biomarkers.
Anthony NG; Baiget J; Berretta G; Boyd M; Breen D; Edwards J; Gamble C; Gray AI; Harvey AL; Hatziieremia S; Ho KH; Huggan JK; Lang S; Llona-Minguez S; Luo JL; McIntosh K; Paul A; Plevin RJ; Robertson MN; Scott R; Suckling CJ; Sutcliffe OB; Young LC; Mackay SP
J Med Chem; 2017 Aug; 60(16):7043-7066. PubMed ID: 28737909
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
