BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

326 related articles for article (PubMed ID: 25390333)

  • 1. Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture.
    Shimamoto A; Kagawa H; Zensho K; Sera Y; Kazuki Y; Osaki M; Oshimura M; Ishigaki Y; Hamasaki K; Kodama Y; Yuasa S; Fukuda K; Hirashima K; Seimiya H; Koyama H; Shimizu T; Takemoto M; Yokote K; Goto M; Tahara H
    PLoS One; 2014; 9(11):e112900. PubMed ID: 25390333
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Werner Syndrome-specific induced pluripotent stem cells: recovery of telomere function by reprogramming.
    Shimamoto A; Yokote K; Tahara H
    Front Genet; 2015; 6():10. PubMed ID: 25688260
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A cascade leading to premature aging phenotypes including abnormal tumor profiles in Werner syndrome (review).
    Sugimoto M
    Int J Mol Med; 2014 Feb; 33(2):247-53. PubMed ID: 24356923
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model.
    Wang S; Liu Z; Ye Y; Li B; Liu T; Zhang W; Liu GH; Zhang YA; Qu J; Xu D; Chen Z
    Cell Death Dis; 2018 Sep; 9(9):923. PubMed ID: 30206203
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Essential role of limiting telomeres in the pathogenesis of Werner syndrome.
    Chang S; Multani AS; Cabrera NG; Naylor ML; Laud P; Lombard D; Pathak S; Guarente L; DePinho RA
    Nat Genet; 2004 Aug; 36(8):877-82. PubMed ID: 15235603
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Utilization of Werner syndrome mouse model in studying premature aging and tumor].
    Jia ST; Yang SH; Luo Y
    Yi Chuan; 2009 Aug; 31(8):785-90. PubMed ID: 19689938
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway.
    Laud PR; Multani AS; Bailey SM; Wu L; Ma J; Kingsley C; Lebel M; Pathak S; DePinho RA; Chang S
    Genes Dev; 2005 Nov; 19(21):2560-70. PubMed ID: 16264192
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Telomere dysfunction as a cause of genomic instability in Werner syndrome.
    Crabbe L; Jauch A; Naeger CM; Holtgreve-Grez H; Karlseder J
    Proc Natl Acad Sci U S A; 2007 Feb; 104(7):2205-10. PubMed ID: 17284601
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Telomerase protects werner syndrome lineage-specific stem cells from premature aging.
    Cheung HH; Liu X; Canterel-Thouennon L; Li L; Edmonson C; Rennert OM
    Stem Cell Reports; 2014 Apr; 2(4):534-46. PubMed ID: 24749076
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prevention of accelerated cell aging in the Werner syndrome.
    Davis T; Haughton MF; Jones CJ; Kipling D
    Ann N Y Acad Sci; 2006 May; 1067():243-7. PubMed ID: 16803993
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased chromosome instability and accumulation of DNA double-strand breaks in Werner syndrome cells.
    Ariyoshi K; Suzuki K; Goto M; Watanabe M; Kodama S
    J Radiat Res; 2007 May; 48(3):219-31. PubMed ID: 17449919
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A mouse model of Werner Syndrome: what can it tell us about aging and cancer?
    Chang S
    Int J Biochem Cell Biol; 2005 May; 37(5):991-9. PubMed ID: 15743673
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Absence of premature senescence in Werner's syndrome keratinocytes.
    Ibrahim B; Sheerin AN; Jennert-Burston K; Bird JL; Massala MV; Illsley M; James SE; Faragher RG
    Exp Gerontol; 2016 Oct; 83():139-47. PubMed ID: 27492502
    [TBL] [Abstract][Full Text] [Related]  

  • 14. WRN at telomeres: implications for aging and cancer.
    Multani AS; Chang S
    J Cell Sci; 2007 Mar; 120(Pt 5):713-21. PubMed ID: 17314245
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induced pluripotent stem cells as a model for telomeric abnormalities in ICF type I syndrome.
    Sagie S; Ellran E; Katzir H; Shaked R; Yehezkel S; Laevsky I; Ghanayim A; Geiger D; Tzukerman M; Selig S
    Hum Mol Genet; 2014 Jul; 23(14):3629-40. PubMed ID: 24549038
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Normal telomere erosion rates at the single cell level in Werner syndrome fibroblast cells.
    Baird DM; Davis T; Rowson J; Jones CJ; Kipling D
    Hum Mol Genet; 2004 Jul; 13(14):1515-24. PubMed ID: 15150162
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhanced telomere rejuvenation in pluripotent cells reprogrammed via nuclear transfer relative to induced pluripotent stem cells.
    Le R; Kou Z; Jiang Y; Li M; Huang B; Liu W; Li H; Kou X; He W; Rudolph KL; Ju Z; Gao S
    Cell Stem Cell; 2014 Jan; 14(1):27-39. PubMed ID: 24268696
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Loss of p21 promoted tumorigenesis in the background of telomere dysfunctions induced by TRF2 and Wrn deficiency.
    Si X; Shao C; Li J; Jia S; Tang W; Zhang J; Yang J; Wu X; Luo Y
    Int J Biol Sci; 2018; 14(2):165-177. PubMed ID: 29483835
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reprogramming of Human Peripheral Blood Mononuclear Cell (PBMC) from a patient suffering of a Werner syndrome resulting in iPSC line (REGUi003-A) maintaining a short telomere length.
    Gatinois V; Desprat R; Becker F; Pichard L; Bernex F; Corsini C; Pellestor F; Lemaitre JM
    Stem Cell Res; 2019 Aug; 39():101515. PubMed ID: 31404747
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes.
    Du X; Shen J; Kugan N; Furth EE; Lombard DB; Cheung C; Pak S; Luo G; Pignolo RJ; DePinho RA; Guarente L; Johnson FB
    Mol Cell Biol; 2004 Oct; 24(19):8437-46. PubMed ID: 15367665
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.