455 related articles for article (PubMed ID: 25391657)
1. A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α.
Chen SJ; Hoffman NE; Shanmughapriya S; Bao L; Keefer K; Conrad K; Merali S; Takahashi Y; Abraham T; Hirschler-Laszkiewicz I; Wang J; Zhang XQ; Song J; Barrero C; Shi Y; Kawasawa YI; Bayerl M; Sun T; Barbour M; Wang HG; Madesh M; Cheung JY; Miller BA
J Biol Chem; 2014 Dec; 289(52):36284-302. PubMed ID: 25391657
[TBL] [Abstract][Full Text] [Related]
2. Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates Its Key Role in Cell Survival through Modulation of Mitochondrial Reactive Oxygen Species and Bioenergetics.
Bao L; Chen SJ; Conrad K; Keefer K; Abraham T; Lee JP; Wang J; Zhang XQ; Hirschler-Laszkiewicz I; Wang HG; Dovat S; Gans B; Madesh M; Cheung JY; Miller BA
J Biol Chem; 2016 Nov; 291(47):24449-24464. PubMed ID: 27694440
[TBL] [Abstract][Full Text] [Related]
3. Role of TRPM2 in cell proliferation and susceptibility to oxidative stress.
Chen SJ; Zhang W; Tong Q; Conrad K; Hirschler-Laszkiewicz I; Bayerl M; Kim JK; Cheung JY; Miller BA
Am J Physiol Cell Physiol; 2013 Mar; 304(6):C548-60. PubMed ID: 23302782
[TBL] [Abstract][Full Text] [Related]
4. TRPM2 in Cancer.
Miller BA
Cell Calcium; 2019 Jun; 80():8-17. PubMed ID: 30925291
[TBL] [Abstract][Full Text] [Related]
5. Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype.
Holmquist-Mengelbier L; Fredlund E; Löfstedt T; Noguera R; Navarro S; Nilsson H; Pietras A; Vallon-Christersson J; Borg A; Gradin K; Poellinger L; Påhlman S
Cancer Cell; 2006 Nov; 10(5):413-23. PubMed ID: 17097563
[TBL] [Abstract][Full Text] [Related]
6. The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation.
Hirschler-Laszkiewicz I; Chen SJ; Bao L; Wang J; Zhang XQ; Shanmughapriya S; Keefer K; Madesh M; Cheung JY; Miller BA
Am J Physiol Cell Physiol; 2018 Oct; 315(4):C571-C586. PubMed ID: 30020827
[TBL] [Abstract][Full Text] [Related]
7. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
Carroll VA; Ashcroft M
Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
[TBL] [Abstract][Full Text] [Related]
8. Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha.
Puppo M; Battaglia F; Ottaviano C; Delfino S; Ribatti D; Varesio L; Bosco MC
Mol Cancer Ther; 2008 Jul; 7(7):1974-84. PubMed ID: 18645007
[TBL] [Abstract][Full Text] [Related]
9. TRPM2 channel-mediated regulation of autophagy maintains mitochondrial function and promotes gastric cancer cell survival via the JNK-signaling pathway.
Almasi S; Kennedy BE; El-Aghil M; Sterea AM; Gujar S; Partida-Sánchez S; El Hiani Y
J Biol Chem; 2018 Mar; 293(10):3637-3650. PubMed ID: 29343514
[TBL] [Abstract][Full Text] [Related]
10. Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.
Nilsson MB; Zage PE; Zeng L; Xu L; Cascone T; Wu HK; Saigal B; Zweidler-McKay PA; Heymach JV
Oncogene; 2010 May; 29(20):2938-49. PubMed ID: 20208561
[TBL] [Abstract][Full Text] [Related]
11. MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha.
Zhang H; Pu J; Qi T; Qi M; Yang C; Li S; Huang K; Zheng L; Tong Q
Oncogene; 2014 Jan; 33(3):387-97. PubMed ID: 23222716
[TBL] [Abstract][Full Text] [Related]
12. Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy.
Chen SJ; Bao L; Keefer K; Shanmughapriya S; Chen L; Lee J; Wang J; Zhang XQ; Hirschler-Laszkiewicz I; Merali S; Merali C; Imamura Y; Dovat S; Madesh M; Cheung JY; Wang HG; Miller BA
Cell Death Dis; 2020 Apr; 11(4):247. PubMed ID: 32312983
[TBL] [Abstract][Full Text] [Related]
13. TRPM2 protects against tissue damage following oxidative stress and ischaemia-reperfusion.
Miller BA; Cheung JY
J Physiol; 2016 Aug; 594(15):4181-91. PubMed ID: 26420388
[TBL] [Abstract][Full Text] [Related]
14. Differential regulation of HIF-1α and HIF-2α in neuroblastoma: Estrogen-related receptor alpha (ERRα) regulates HIF2A transcription and correlates to poor outcome.
Hamidian A; von Stedingk K; Munksgaard Thorén M; Mohlin S; Påhlman S
Biochem Biophys Res Commun; 2015 Jun; 461(3):560-7. PubMed ID: 25912138
[TBL] [Abstract][Full Text] [Related]
15. Roles of hypoxia-inducible factor-1alpha (HIF-1alpha) versus HIF-2alpha in the survival of hepatocellular tumor spheroids.
Menrad H; Werno C; Schmid T; Copanaki E; Deller T; Dehne N; Brüne B
Hepatology; 2010 Jun; 51(6):2183-92. PubMed ID: 20513003
[TBL] [Abstract][Full Text] [Related]
16. Hypoxia inducible factor 1α and hypoxia inducible factor 2α play distinct and functionally overlapping roles in oral squamous cell carcinoma.
Zhu GQ; Tang YL; Li L; Zheng M; Jiang J; Li XY; Chen SX; Liang XH
Clin Cancer Res; 2010 Oct; 16(19):4732-41. PubMed ID: 20807755
[TBL] [Abstract][Full Text] [Related]
17. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
[TBL] [Abstract][Full Text] [Related]
18. microRNA-558 facilitates the expression of hypoxia-inducible factor 2 alpha through binding to 5'-untranslated region in neuroblastoma.
Qu H; Zheng L; Song H; Jiao W; Li D; Fang E; Wang X; Mei H; Pu J; Huang K; Tong Q
Oncotarget; 2016 Jun; 7(26):40657-40673. PubMed ID: 27276678
[TBL] [Abstract][Full Text] [Related]
19. ARNT-dependent HIF-2 transcriptional activity is not sufficient to regulate downstream target genes in neuroblastoma.
Persson CU; von Stedingk K; Fredlund E; Bexell D; Påhlman S; Wigerup C; Mohlin S
Exp Cell Res; 2020 Mar; 388(2):111845. PubMed ID: 31945318
[TBL] [Abstract][Full Text] [Related]
20. Hypoxia-inducible factor-2α directly promotes BCRP expression and mediates the resistance of ovarian cancer stem cells to adriamycin.
He M; Wu H; Jiang Q; Liu Y; Han L; Yan Y; Wei B; Liu F; Deng X; Chen H; Zhao L; Wang M; Wu X; Yao W; Zhao H; Chen J; Wei M
Mol Oncol; 2019 Feb; 13(2):403-421. PubMed ID: 30536571
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
