BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

254 related articles for article (PubMed ID: 25395352)

  • 21. Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus.
    Jaber N; Mohd-Naim N; Wang Z; DeLeon JL; Kim S; Zhong H; Sheshadri N; Dou Z; Edinger AL; Du G; Braga VM; Zong WX
    J Cell Sci; 2016 Dec; 129(23):4424-4435. PubMed ID: 27793976
    [TBL] [Abstract][Full Text] [Related]  

  • 22. In Vitro Characterization of VPS34 Lipid Kinase Inhibition by Small Molecules.
    Fassy F; Dureuil C; Lamberton A; Mathieu M; Michot N; Ronan B; Pasquier B
    Methods Enzymol; 2017; 587():447-464. PubMed ID: 28253972
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Differential regulatory functions of three classes of phosphatidylinositol and phosphoinositide 3-kinases in autophagy.
    Yu X; Long YC; Shen HM
    Autophagy; 2015; 11(10):1711-28. PubMed ID: 26018563
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Regulation of class III (Vps34) PI3Ks.
    Yan Y; Backer JM
    Biochem Soc Trans; 2007 Apr; 35(Pt 2):239-41. PubMed ID: 17371248
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.
    Stack JH; Emr SD
    J Biol Chem; 1994 Dec; 269(50):31552-62. PubMed ID: 7989323
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The class III phosphatidylinositol 3-kinase Vps34 in Saccharomyces cerevisiae.
    Reidick C; Boutouja F; Platta HW
    Biol Chem; 2017 May; 398(5-6):677-685. PubMed ID: 27935849
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasis.
    Ikonomov OC; Sbrissa D; Venkatareddy M; Tisdale E; Garg P; Shisheva A
    Biochim Biophys Acta; 2015 May; 1853(5):1240-50. PubMed ID: 25619930
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Ironing out VPS34 inhibition.
    Marsh T; Debnath J
    Nat Cell Biol; 2015 Jan; 17(1):1-3. PubMed ID: 25679028
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Discovery of (2S)-8-[(3R)-3-methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyrimido[1,2-a]pyrimidin-6-one: a novel potent and selective inhibitor of Vps34 for the treatment of solid tumors.
    Pasquier B; El-Ahmad Y; Filoche-Rommé B; Dureuil C; Fassy F; Abecassis PY; Mathieu M; Bertrand T; Benard T; Barrière C; El Batti S; Letallec JP; Sonnefraud V; Brollo M; Delbarre L; Loyau V; Pilorge F; Bertin L; Richepin P; Arigon J; Labrosse JR; Clément J; Durand F; Combet R; Perraut P; Leroy V; Gay F; Lefrançois D; Bretin F; Marquette JP; Michot N; Caron A; Castell C; Schio L; McCort G; Goulaouic H; Garcia-Echeverria C; Ronan B
    J Med Chem; 2015 Jan; 58(1):376-400. PubMed ID: 25402320
    [TBL] [Abstract][Full Text] [Related]  

  • 30. NRBF2 regulates macroautophagy as a component of Vps34 Complex I.
    Cao Y; Wang Y; Abi Saab WF; Yang F; Pessin JE; Backer JM
    Biochem J; 2014 Jul; 461(2):315-22. PubMed ID: 24785657
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Antileukemic activity of the VPS34-IN1 inhibitor in acute myeloid leukemia.
    Meunier G; Birsen R; Cazelles C; Belhadj M; Cantero-Aguilar L; Kosmider O; Fontenay M; Azar N; Mayeux P; Chapuis N; Tamburini J; Bouscary D
    Oncogenesis; 2020 Oct; 9(10):94. PubMed ID: 33093450
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The VPS34 PI3K negatively regulates RAB-5 during endosome maturation.
    Law F; Seo JH; Wang Z; DeLeon JL; Bolis Y; Brown A; Zong WX; Du G; Rocheleau CE
    J Cell Sci; 2017 Jun; 130(12):2007-2017. PubMed ID: 28455411
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Shaping development of autophagy inhibitors with the structure of the lipid kinase Vps34.
    Miller S; Tavshanjian B; Oleksy A; Perisic O; Houseman BT; Shokat KM; Williams RL
    Science; 2010 Mar; 327(5973):1638-42. PubMed ID: 20339072
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes.
    Tremel S; Ohashi Y; Morado DR; Bertram J; Perisic O; Brandt LTL; von Wrisberg MK; Chen ZA; Maslen SL; Kovtun O; Skehel M; Rappsilber J; Lang K; Munro S; Briggs JAG; Williams RL
    Nat Commun; 2021 Mar; 12(1):1564. PubMed ID: 33692360
    [TBL] [Abstract][Full Text] [Related]  

  • 35. FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation.
    Xiao J; Zhang T; Xu D; Wang H; Cai Y; Jin T; Liu M; Jin M; Wu K; Yuan J
    Genes Dev; 2015 Jan; 29(2):184-96. PubMed ID: 25593308
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Inhibition of lipid kinase PIKfyve reveals a role for phosphatase Inpp4b in the regulation of PI(3)P-mediated lysosome dynamics through VPS34 activity.
    Saffi GT; Wang CA; Mangialardi EM; Vacher J; Botelho RJ; Salmena L
    J Biol Chem; 2022 Aug; 298(8):102187. PubMed ID: 35760104
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Suppression of SARS-CoV-2 infection in ex-vivo human lung tissues by targeting class III phosphoinositide 3-kinase.
    Yuen CK; Wong WM; Mak LF; Wang X; Chu H; Yuen KY; Kok KH
    J Med Virol; 2021 Apr; 93(4):2076-2083. PubMed ID: 33026649
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Beclin 1-ATG14L Protein-Protein Interaction Inhibitor Selectively Inhibits Autophagy through Disruption of VPS34 Complex I.
    Pavlinov I; Salkovski M; Aldrich LN
    J Am Chem Soc; 2020 May; 142(18):8174-8182. PubMed ID: 32320221
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC.
    Friedrich B; Feng Y; Cohen P; Risler T; Vandewalle A; Bröer S; Wang J; Pearce D; Lang F
    Pflugers Arch; 2003 Mar; 445(6):693-6. PubMed ID: 12632189
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Phosphoinositide 3-kinases in platelets, thrombosis and therapeutics.
    Ribes A; Oprescu A; Viaud J; Hnia K; Chicanne G; Xuereb JM; Severin S; Gratacap MP; Payrastre B
    Biochem J; 2020 Nov; 477(22):4327-4342. PubMed ID: 33242335
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.