BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

333 related articles for article (PubMed ID: 25398949)

  • 1. Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease.
    Francelle L; Galvan L; Gaillard MC; Guillermier M; Houitte D; Bonvento G; Petit F; Jan C; Dufour N; Hantraye P; Elalouf JM; De Chaldée M; Déglon N; Brouillet E
    Hum Mol Genet; 2015 Mar; 24(6):1563-73. PubMed ID: 25398949
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synaptic scaling up in medium spiny neurons of aged BACHD mice: A slow-progression model of Huntington's disease.
    Rocher AB; Gubellini P; Merienne N; Boussicault L; Petit F; Gipchtein P; Jan C; Hantraye P; Brouillet E; Bonvento G
    Neurobiol Dis; 2016 Feb; 86():131-9. PubMed ID: 26626081
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.
    Wang N; Gray M; Lu XH; Cantle JP; Holley SM; Greiner E; Gu X; Shirasaki D; Cepeda C; Li Y; Dong H; Levine MS; Yang XW
    Nat Med; 2014 May; 20(5):536-41. PubMed ID: 24784230
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington's disease.
    Zhao X; Chen XQ; Han E; Hu Y; Paik P; Ding Z; Overman J; Lau AL; Shahmoradian SH; Chiu W; Thompson LM; Wu C; Mobley WC
    Proc Natl Acad Sci U S A; 2016 Sep; 113(38):E5655-64. PubMed ID: 27601642
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cortical efferents lacking mutant huntingtin improve striatal neuronal activity and behavior in a conditional mouse model of Huntington's disease.
    Estrada-Sánchez AM; Burroughs CL; Cavaliere S; Barton SJ; Chen S; Yang XW; Rebec GV
    J Neurosci; 2015 Mar; 35(10):4440-51. PubMed ID: 25762686
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Capucin does not modify the toxicity of a mutant Huntingtin fragment in vivo.
    Galvan L; Lepejová N; Gaillard MC; Malgorn C; Guillermier M; Houitte D; Bonvento G; Petit F; Dufour N; Héry P; Gérard M; Elalouf JM; Déglon N; Brouillet E; de Chaldée M
    Neurobiol Aging; 2012 Aug; 33(8):1845.e5-6. PubMed ID: 22365050
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nature and cause of mitochondrial dysfunction in Huntington's disease: focusing on huntingtin and the striatum.
    Oliveira JM
    J Neurochem; 2010 Jul; 114(1):1-12. PubMed ID: 20403078
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin.
    Galvan L; Francelle L; Gaillard MC; de Longprez L; Carrillo-de Sauvage MA; Liot G; Cambon K; Stimmer L; Luccantoni S; Flament J; Valette J; de Chaldée M; Auregan G; Guillermier M; Joséphine C; Petit F; Jan C; Jarrige M; Dufour N; Bonvento G; Humbert S; Saudou F; Hantraye P; Merienne K; Bemelmans AP; Perrier AL; Déglon N; Brouillet E
    Brain; 2018 May; 141(5):1434-1454. PubMed ID: 29534157
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutant Huntingtin Inhibits αB-Crystallin Expression and Impairs Exosome Secretion from Astrocytes.
    Hong Y; Zhao T; Li XJ; Li S
    J Neurosci; 2017 Sep; 37(39):9550-9563. PubMed ID: 28893927
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease.
    Swarnkar S; Chen Y; Pryor WM; Shahani N; Page DT; Subramaniam S
    Neurobiol Dis; 2015 Oct; 82():66-77. PubMed ID: 26048156
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin.
    Damiano M; Diguet E; Malgorn C; D'Aurelio M; Galvan L; Petit F; Benhaim L; Guillermier M; Houitte D; Dufour N; Hantraye P; Canals JM; Alberch J; Delzescaux T; Déglon N; Beal MF; Brouillet E
    Hum Mol Genet; 2013 Oct; 22(19):3869-82. PubMed ID: 23720495
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of Exogenous NUB1 Expression in the Striatum of HDQ175/Q7 Mice.
    Vodicka P; Chase K; Iuliano M; Valentine DT; Sapp E; Lu B; Kegel-Gleason KB; Sena-Esteves M; Aronin N; DiFiglia M
    J Huntingtons Dis; 2016 Jun; 5(2):163-74. PubMed ID: 27314618
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neocortical expression of mutant huntingtin is not required for alterations in striatal gene expression or motor dysfunction in a transgenic mouse.
    Brown TB; Bogush AI; Ehrlich ME
    Hum Mol Genet; 2008 Oct; 17(20):3095-104. PubMed ID: 18632688
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease.
    Liu KY; Shyu YC; Barbaro BA; Lin YT; Chern Y; Thompson LM; James Shen CK; Marsh JL
    Hum Mol Genet; 2015 Mar; 24(6):1602-16. PubMed ID: 25398943
    [TBL] [Abstract][Full Text] [Related]  

  • 15. AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease.
    Ju TC; Chen HM; Chen YC; Chang CP; Chang C; Chern Y
    Biochim Biophys Acta; 2014 Sep; 1842(9):1668-80. PubMed ID: 24946181
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Autophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice.
    Vodicka P; Chase K; Iuliano M; Tousley A; Valentine DT; Sapp E; Kegel-Gleason KB; Sena-Esteves M; Aronin N; DiFiglia M
    J Huntingtons Dis; 2016 Oct; 5(3):249-260. PubMed ID: 27689619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.
    Kuhn A; Goldstein DR; Hodges A; Strand AD; Sengstag T; Kooperberg C; Becanovic K; Pouladi MA; Sathasivam K; Cha JH; Hannan AJ; Hayden MR; Leavitt BR; Dunnett SB; Ferrante RJ; Albin R; Shelbourne P; Delorenzi M; Augood SJ; Faull RL; Olson JM; Bates GP; Jones L; Luthi-Carter R
    Hum Mol Genet; 2007 Aug; 16(15):1845-61. PubMed ID: 17519223
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reduced Expression of Foxp1 as a Contributing Factor in Huntington's Disease.
    Louis Sam Titus ASC; Yusuff T; Cassar M; Thomas E; Kretzschmar D; D'Mello SR
    J Neurosci; 2017 Jul; 37(27):6575-6587. PubMed ID: 28550168
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of striatal 90-kDa ribosomal S6 kinase (Rsk) is a key factor for motor, synaptic and transcription dysfunction in Huntington's disease.
    Anglada-Huguet M; Giralt A; Rué L; Alberch J; Xifró X
    Biochim Biophys Acta; 2016 Jul; 1862(7):1255-66. PubMed ID: 27063456
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo.
    Francelle L; Galvan L; Gaillard MC; Petit F; Bernay B; Guillermier M; Bonvento G; Dufour N; Elalouf JM; Hantraye P; Déglon N; de Chaldée M; Brouillet E
    Neurobiol Aging; 2015 Mar; 36(3):1601.e7-16. PubMed ID: 25619660
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.