233 related articles for article (PubMed ID: 25400026)
1. Disulfide-mediated stabilization of the IκB kinase binding domain of NF-κB essential modulator (NEMO).
Zhou L; Yeo AT; Ballarano C; Weber U; Allen KN; Gilmore TD; Whitty A
Biochemistry; 2014 Dec; 53(50):7929-44. PubMed ID: 25400026
[TBL] [Abstract][Full Text] [Related]
2. Mutation of nonessential cysteines shows that the NF-κB essential modulator forms a constitutive noncovalent dimer that binds IκB kinase-β with high affinity.
Cote SM; Gilmore TD; Shaffer R; Weber U; Bollam R; Golden MS; Glover K; Herscovitch M; Ennis T; Allen KN; Whitty A
Biochemistry; 2013 Dec; 52(51):9141-54. PubMed ID: 24266532
[TBL] [Abstract][Full Text] [Related]
3. NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation.
Solt LA; Madge LA; May MJ
J Biol Chem; 2009 Oct; 284(40):27596-608. PubMed ID: 19666475
[TBL] [Abstract][Full Text] [Related]
4. Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347.
Herscovitch M; Comb W; Ennis T; Coleman K; Yong S; Armstead B; Kalaitzidis D; Chandani S; Gilmore TD
Biochem Biophys Res Commun; 2008 Feb; 367(1):103-8. PubMed ID: 18164680
[TBL] [Abstract][Full Text] [Related]
5. Novel non-peptide small molecules preventing IKKβ/NEMO association inhibit NF-κB activation in LPS-stimulated J774 macrophages.
De Falco F; Di Giovanni C; Cerchia C; De Stefano D; Capuozzo A; Irace C; Iuvone T; Santamaria R; Carnuccio R; Lavecchia A
Biochem Pharmacol; 2016 Mar; 104():83-94. PubMed ID: 26776306
[TBL] [Abstract][Full Text] [Related]
6. NEMO oligomerization and its ubiquitin-binding properties.
Ivins FJ; Montgomery MG; Smith SJ; Morris-Davies AC; Taylor IA; Rittinger K
Biochem J; 2009 Jun; 421(2):243-51. PubMed ID: 19422324
[TBL] [Abstract][Full Text] [Related]
7. Dimer of arfaptin 2 regulates NF-κB signaling by interacting with IKKβ/NEMO and inhibiting IKKβ kinase activity.
You DJ; Park CR; Furlong M; Koo O; Lee C; Ahn C; Seong JY; Hwang JI
Cell Signal; 2015 Nov; 27(11):2173-81. PubMed ID: 26296658
[TBL] [Abstract][Full Text] [Related]
8. Phosphorylation of serine 68 in the IkappaB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-alpha-induced NF-kappaB activity.
Palkowitsch L; Leidner J; Ghosh S; Marienfeld RB
J Biol Chem; 2008 Jan; 283(1):76-86. PubMed ID: 17977820
[TBL] [Abstract][Full Text] [Related]
9. DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding.
Grubisha O; Kaminska M; Duquerroy S; Fontan E; Cordier F; Haouz A; Raynal B; Chiaravalli J; Delepierre M; Israël A; Véron M; Agou F
J Mol Biol; 2010 Jan; 395(1):89-104. PubMed ID: 19854204
[TBL] [Abstract][Full Text] [Related]
10. Dimerization of the I kappa B kinase-binding domain of NEMO is required for tumor necrosis factor alpha-induced NF-kappa B activity.
Marienfeld RB; Palkowitsch L; Ghosh S
Mol Cell Biol; 2006 Dec; 26(24):9209-19. PubMed ID: 17000764
[TBL] [Abstract][Full Text] [Related]
11. Identification of a new NEMO/TRAF6 interface affected in incontinentia pigmenti pathology.
Gautheron J; Pescatore A; Fusco F; Esposito E; Yamaoka S; Agou F; Ursini MV; Courtois G
Hum Mol Genet; 2010 Aug; 19(16):3138-49. PubMed ID: 20529958
[TBL] [Abstract][Full Text] [Related]
12. Interleukin-1-induced NF-kappaB activation is NEMO-dependent but does not require IKKbeta.
Solt LA; Madge LA; Orange JS; May MJ
J Biol Chem; 2007 Mar; 282(12):8724-33. PubMed ID: 17244613
[TBL] [Abstract][Full Text] [Related]
13. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected].
Wu CJ; Conze DB; Li T; Srinivasula SM; Ashwell JD
Nat Cell Biol; 2006 Apr; 8(4):398-406. PubMed ID: 16547522
[TBL] [Abstract][Full Text] [Related]
14. Structurally plastic NEMO and oligomerization prone IKK2 subunits define the behavior of human IKK2:NEMO complexes in solution.
Ko MS; Biswas T; Mulero MC; Bobkov AA; Ghosh G; Huxford T
Biochim Biophys Acta Proteins Proteom; 2020 Dec; 1868(12):140526. PubMed ID: 32853772
[TBL] [Abstract][Full Text] [Related]
15. Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC.
Matta H; Gopalakrishnan R; Graham C; Tolani B; Khanna A; Yi H; Suo Y; Chaudhary PM
PLoS One; 2012; 7(5):e36601. PubMed ID: 22590573
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of the NEMO/IKKβ association complex formation, a novel mechanism associated with the NF-κB activation suppression by Withania somnifera's key metabolite withaferin A.
Grover A; Shandilya A; Punetha A; Bisaria VS; Sundar D
BMC Genomics; 2010 Dec; 11 Suppl 4(Suppl 4):S25. PubMed ID: 21143809
[TBL] [Abstract][Full Text] [Related]
17. Covalent modification of the NF-κB essential modulator (NEMO) by a chemical compound can regulate its ubiquitin binding properties in vitro.
Hooper C; Jackson SS; Coughlin EE; Coon JJ; Miyamoto S
J Biol Chem; 2014 Nov; 289(48):33161-74. PubMed ID: 25296760
[TBL] [Abstract][Full Text] [Related]
18. Protein engineering of the N-terminus of NEMO: structure stabilization and rescue of IKKβ binding.
Guo B; Audu CO; Cochran JC; Mierke DF; Pellegrini M
Biochemistry; 2014 Nov; 53(43):6776-85. PubMed ID: 25286246
[TBL] [Abstract][Full Text] [Related]
19. Regulation and function of IKK and IKK-related kinases.
Häcker H; Karin M
Sci STKE; 2006 Oct; 2006(357):re13. PubMed ID: 17047224
[TBL] [Abstract][Full Text] [Related]
20. NEMO oligomerization in the dynamic assembly of the IkappaB kinase core complex.
Fontan E; Traincard F; Levy SG; Yamaoka S; Véron M; Agou F
FEBS J; 2007 May; 274(10):2540-51. PubMed ID: 17419723
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
