BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 25404202)

  • 1. Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.
    Richter J; Ullah K; Xu P; Alscher V; Blatz A; Peifer C; Halekotte J; Leban J; Vitt D; Holzmann K; Bakulev V; Pinna LA; Henne-Bruns D; Hillenbrand A; Kornmann M; Leithäuser F; Bischof J; Knippschild U
    Int J Cancer; 2015 Jun; 136(12):2799-810. PubMed ID: 25404202
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The CK1δ/ε-AES axis regulates tumorigenesis and metastasis in colorectal cancer.
    Wang Z; Zhou L; Wang Y; Peng Q; Li H; Zhang X; Su Z; Song J; Sun Q; Sayed S; Liu S; Lu D
    Theranostics; 2021; 11(9):4421-4435. PubMed ID: 33754069
    [No Abstract]   [Full Text] [Related]  

  • 3. Decreased CK1δ expression predicts prolonged survival in colorectal cancer patients.
    Richter J; Rudeck S; Kretz AL; Kramer K; Just S; Henne-Bruns D; Hillenbrand A; Leithäuser F; Lemke J; Knippschild U
    Tumour Biol; 2016 Jul; 37(7):8731-9. PubMed ID: 26738869
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Newly Developed CK1-Specific Inhibitors Show Specifically Stronger Effects on CK1 Mutants and Colon Cancer Cell Lines.
    Liu C; Witt L; Ianes C; Bischof J; Bammert MT; Baier J; Kirschner S; Henne-Bruns D; Xu P; Kornmann M; Peifer C; Knippschild U
    Int J Mol Sci; 2019 Dec; 20(24):. PubMed ID: 31817920
    [TBL] [Abstract][Full Text] [Related]  

  • 5. IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation.
    Cheong JK; Nguyen TH; Wang H; Tan P; Voorhoeve PM; Lee SH; Virshup DM
    Oncogene; 2011 Jun; 30(22):2558-69. PubMed ID: 21258417
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivo.
    Hirner H; Günes C; Bischof J; Wolff S; Grothey A; Kühl M; Oswald F; Wegwitz F; Bösl MR; Trauzold A; Henne-Bruns D; Peifer C; Leithäuser F; Deppert W; Knippschild U
    PLoS One; 2012; 7(1):e29709. PubMed ID: 22235331
    [TBL] [Abstract][Full Text] [Related]  

  • 7. IC261 suppresses progression of hepatocellular carcinoma in a casein kinase 1 δ/ε independent manner.
    Yuan F; Li D; Guo M; Fang T; Sun J; Qi F; Rao Q; Zhao Z; Huang P; Yang B; Xia J
    Biochem Biophys Res Commun; 2020 Mar; 523(3):809-815. PubMed ID: 31954519
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CK1α overexpression correlates with poor survival in colorectal cancer.
    Richter J; Kretz AL; Lemke J; Fauler M; Werner JU; Paschke S; Leithäuser F; Henne-Bruns D; Hillenbrand A; Knippschild U
    BMC Cancer; 2018 Feb; 18(1):140. PubMed ID: 29409464
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Therapeutic targeting of casein kinase 1δ in breast cancer.
    Rosenberg LH; Lafitte M; Quereda V; Grant W; Chen W; Bibian M; Noguchi Y; Fallahi M; Yang C; Chang JC; Roush WR; Cleveland JL; Duckett DR
    Sci Transl Med; 2015 Dec; 7(318):318ra202. PubMed ID: 26676609
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε.
    García-Reyes B; Witt L; Jansen B; Karasu E; Gehring T; Leban J; Henne-Bruns D; Pichlo C; Brunstein E; Baumann U; Wesseler F; Rathmer B; Schade D; Peifer C; Knippschild U
    J Med Chem; 2018 May; 61(9):4087-4102. PubMed ID: 29630366
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Casein kinase 1 is a therapeutic target in chronic lymphocytic leukemia.
    Janovska P; Verner J; Kohoutek J; Bryjova L; Gregorova M; Dzimkova M; Skabrahova H; Radaszkiewicz T; Ovesna P; Vondalova Blanarova O; Nemcova T; Hoferova Z; Vasickova K; Smyckova L; Egle A; Pavlova S; Poppova L; Plevova K; Pospisilova S; Bryja V
    Blood; 2018 Mar; 131(11):1206-1218. PubMed ID: 29317454
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Casein kinase 1α has a non-redundant and dominant role within the CK1 family in melanoma progression.
    Sinnberg T; Wang J; Sauer B; Schittek B
    BMC Cancer; 2016 Aug; 16():594. PubMed ID: 27488834
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Difluoro-dioxolo-benzoimidazol-benzamides as potent inhibitors of CK1δ and ε with nanomolar inhibitory activity on cancer cell proliferation.
    Richter J; Bischof J; Zaja M; Kohlhof H; Othersen O; Vitt D; Alscher V; Pospiech I; García-Reyes B; Berg S; Leban J; Knippschild U
    J Med Chem; 2014 Oct; 57(19):7933-46. PubMed ID: 25191940
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CK1δ activity is modulated by CDK2/E- and CDK5/p35-mediated phosphorylation.
    Ianes C; Xu P; Werz N; Meng Z; Henne-Bruns D; Bischof J; Knippschild U
    Amino Acids; 2016 Feb; 48(2):579-92. PubMed ID: 26464264
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CK1α, CK1δ, and CK1ε are necrosome components which phosphorylate serine 227 of human RIPK3 to activate necroptosis.
    Hanna-Addams S; Liu S; Liu H; Chen S; Wang Z
    Proc Natl Acad Sci U S A; 2020 Jan; 117(4):1962-1970. PubMed ID: 31932442
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RNAi-mediated downregulation of DNA binding protein A inhibits tumorigenesis in colorectal cancer.
    Liu RT; Wang GR; Liu C; Qiu J; Yan LK; Li XJ; Wang XQ
    Int J Mol Med; 2016 Sep; 38(3):703-12. PubMed ID: 27430286
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of colorectal carcinoma stemness, growth, and metastasis by an miR-200c-Sox2-negative feedback loop mechanism.
    Lu YX; Yuan L; Xue XL; Zhou M; Liu Y; Zhang C; Li JP; Zheng L; Hong M; Li XN
    Clin Cancer Res; 2014 May; 20(10):2631-42. PubMed ID: 24658157
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular basis for the regulation of the circadian clock kinases CK1δ and CK1ε.
    Yang Y; Xu T; Zhang Y; Qin X
    Cell Signal; 2017 Feb; 31():58-65. PubMed ID: 28057520
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CK1δ kinase activity is modulated by protein kinase C α (PKCα)-mediated site-specific phosphorylation.
    Meng Z; Bischof J; Ianes C; Henne-Bruns D; Xu P; Knippschild U
    Amino Acids; 2016 May; 48(5):1185-97. PubMed ID: 26803658
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivo.
    Brockschmidt C; Hirner H; Huber N; Eismann T; Hillenbrand A; Giamas G; Radunsky B; Ammerpohl O; Bohm B; Henne-Bruns D; Kalthoff H; Leithäuser F; Trauzold A; Knippschild U
    Gut; 2008 Jun; 57(6):799-806. PubMed ID: 18203806
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.