These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 2540747)

  • 1. Topoisomerase II: a potential target for novel antifungal agents.
    Figgitt DP; Denyer SP; Dewick PM; Jackson DE; Williams P
    Biochem Biophys Res Commun; 1989 Apr; 160(1):257-62. PubMed ID: 2540747
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Exploiting mechanistic differences between drug classes to define functional drug interaction domains on topoisomerase II. Evidence that several diverse DNA cleavage-enhancing agents share a common site of action on the enzyme.
    Corbett AH; Hong D; Osheroff N
    J Biol Chem; 1993 Jul; 268(19):14394-8. PubMed ID: 8390992
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Topoisomerase-II-mediated lesions in nascent DNA: comparison of the effects of epipodophyllotoxin derivatives, VM-26 and VP-16, and 9-anilinoacridine derivatives, m-AMSA and o-AMSA.
    Woynarowski JM; Sigmund RD; Beerman TA
    Biochim Biophys Acta; 1988 May; 950(1):21-9. PubMed ID: 2833925
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: evidence for distinct drug interaction domains on topoisomerase II.
    Robinson MJ; Corbett AH; Osheroff N
    Biochemistry; 1993 Apr; 32(14):3638-43. PubMed ID: 8385484
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aurintricarboxylic acid, a putative inhibitor of apoptosis, is a potent inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells.
    Benchokroun Y; Couprie J; Larsen AK
    Biochem Pharmacol; 1995 Jan; 49(3):305-13. PubMed ID: 7857317
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The interaction between nuclear topoisomerase II activity from human leukemia cells, exogenous DNA, and 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) or 4-(4,6-O-ethylidene-beta-D-glucopyranoside) (VP-16) indicates the sensitivity of the cells to the drugs.
    Estey EH; Silberman L; Beran M; Andersson BS; Zwelling LA
    Biochem Biophys Res Commun; 1987 Apr; 144(2):787-93. PubMed ID: 3034264
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Response of purified mitochondrial DNA topoisomerase I from bovine liver to camptothecin and m-AMSA.
    Lin JH; Castora FJ
    Arch Biochem Biophys; 1995 Dec; 324(2):293-9. PubMed ID: 8554321
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differentiation of human promonocytic leukemia U-937 cells with DNA topoisomerase II inhibitors: induction of vimentin gene expression.
    Rius C; Zorrilla AR; CabaƱas C; Mata F; Bernabeu C; Aller P
    Mol Pharmacol; 1991 Apr; 39(4):442-8. PubMed ID: 1850089
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human small cell lung cancer NYH cells selected for resistance to the bisdioxopiperazine topoisomerase II catalytic inhibitor ICRF-187 demonstrate a functional R162Q mutation in the Walker A consensus ATP binding domain of the alpha isoform.
    Wessel I; Jensen LH; Jensen PB; Falck J; Rose A; Roerth M; Nitiss JL; Sehested M
    Cancer Res; 1999 Jul; 59(14):3442-50. PubMed ID: 10416608
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amsacrine and etoposide hypersensitivity of yeast cells overexpressing DNA topoisomerase II.
    Nitiss JL; Liu YX; Harbury P; Jannatipour M; Wasserman R; Wang JC
    Cancer Res; 1992 Aug; 52(16):4467-72. PubMed ID: 1322791
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evidence for a common mechanism of action for antitumor and antibacterial agents that inhibit type II DNA topoisomerases.
    Huff AC; Kreuzer KN
    J Biol Chem; 1990 Nov; 265(33):20496-505. PubMed ID: 2173709
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Yeast cells expressing differential levels of human or yeast DNA topoisomerase II: a potent tool for identification and characterization of topoisomerase II-targeting antitumour agents.
    van Hille B; Hill BT
    Cancer Chemother Pharmacol; 1998; 42(5):345-56. PubMed ID: 9771947
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antitumor agents. 78. Inhibition of human DNA topoisomerase II by podophyllotoxin and alpha-peltatin analogues.
    Thurston LS; Irie H; Tani S; Han FS; Liu ZC; Cheng YC; Lee KH
    J Med Chem; 1986 Aug; 29(8):1547-50. PubMed ID: 3016271
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elevated topoisomerase II activity and altered chromatin in nitrogen mustard-resistant human cells.
    Tan KB; Mattern MR; Boyce RA; Hertzberg RP; Schein PS
    NCI Monogr; 1987; (4):95-8. PubMed ID: 2819739
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Relative activity of structural analogues of amsacrine against human leukemia cell lines containing amsacrine-sensitive or -resistant forms of topoisomerase II: use of computer simulations in new drug development.
    Zwelling LA; Mitchell MJ; Satitpunwaycha P; Mayes J; Altschuler E; Hinds M; Baguley BC
    Cancer Res; 1992 Jan; 52(1):209-17. PubMed ID: 1309224
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antitumor agents. 124. New 4 beta-substituted aniline derivatives of 6,7-O,O-demethylene-4'-O-demethylpodophyllotoxin and related compounds as potent inhibitors of human DNA topoisomerase II.
    Wang ZQ; Hu H; Chen HX; Cheng YC; Lee KH
    J Med Chem; 1992 Mar; 35(5):871-7. PubMed ID: 1312601
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antitumor agents. I. DNA topoisomerase II inhibitory activity and the structural relationship of podophyllotoxin derivatives as antitumor agents.
    Terada T; Fujimoto K; Nomura M; Yamashita J; Kobunai T; Takeda S; Wierzba K; Yamada Y; Yamaguchi H
    Chem Pharm Bull (Tokyo); 1992 Oct; 40(10):2720-7. PubMed ID: 1334447
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Podophyllotoxin aza-analogue, a novel DNA topoisomerase II inhibitor.
    Iida A; Kano M; Kubota Y; Koga K; Tomioka K
    Chem Pharm Bull (Tokyo); 2000 Apr; 48(4):486-9. PubMed ID: 10783066
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novobiocin, nalidixic acid, etoposide, and 4'-(9-acridinylamino)methanesulfon-m-anisidide effects on G2 and mitotic Chinese hamster ovary cell progression.
    Rowley R; Kort L
    Cancer Res; 1989 Sep; 49(17):4752-7. PubMed ID: 2474373
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antitumor agents. 111. New 4-hydroxylated and 4-halogenated anilino derivatives of 4'-demethylepipodophyllotoxin as potent inhibitors of human DNA topoisomerase II.
    Lee KH; Beers SA; Mori M; Wang ZQ; Kuo YH; Li L; Liu SY; Chang JY; Han FS; Cheng YC
    J Med Chem; 1990 May; 33(5):1364-8. PubMed ID: 2158562
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.