BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 25412146)

  • 1. Regiospecific formation of cobamide isomers is directed by CobT.
    Crofts TS; Hazra AB; Tran JL; Sokolovskaya OM; Osadchiy V; Ad O; Pelton J; Bauer S; Taga ME
    Biochemistry; 2014 Dec; 53(49):7805-15. PubMed ID: 25412146
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cobamide structure depends on both lower ligand availability and CobT substrate specificity.
    Crofts TS; Seth EC; Hazra AB; Taga ME
    Chem Biol; 2013 Oct; 20(10):1265-74. PubMed ID: 24055007
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analysis of substrate specificity in CobT homologs reveals widespread preference for DMB, the lower axial ligand of vitamin B(12).
    Hazra AB; Tran JL; Crofts TS; Taga ME
    Chem Biol; 2013 Oct; 20(10):1275-85. PubMed ID: 24055005
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dissecting cobamide diversity through structural and functional analyses of the base-activating CobT enzyme of Salmonella enterica.
    Chan CH; Newmister SA; Talyor K; Claas KR; Rayment I; Escalante-Semerena JC
    Biochim Biophys Acta; 2014 Jan; 1840(1):464-75. PubMed ID: 24121107
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural investigation of the biosynthesis of alternative lower ligands for cobamides by nicotinate mononucleotide: 5,6-dimethylbenzimidazole phosphoribosyltransferase from Salmonella enterica.
    Cheong CG; Escalante-Semerena JC; Rayment I
    J Biol Chem; 2001 Oct; 276(40):37612-20. PubMed ID: 11441022
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CobT and BzaC catalyze the regiospecific activation and methylation of the 5-hydroxybenzimidazole lower ligand in anaerobic cobamide biosynthesis.
    Mathur Y; Sreyas S; Datar PM; Sathian MB; Hazra AB
    J Biol Chem; 2020 Jul; 295(31):10522-10534. PubMed ID: 32503839
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A New Class of Phosphoribosyltransferases Involved in Cobamide Biosynthesis Is Found in Methanogenic Archaea and Cyanobacteria.
    Jeter VL; Mattes TA; Beattie NR; Escalante-Semerena JC
    Biochemistry; 2019 Feb; 58(7):951-964. PubMed ID: 30640434
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro synthesis of the nucleotide loop of cobalamin by Salmonella typhimurium enzymes.
    Maggio-Hall LA; Escalante-Semerena JC
    Proc Natl Acad Sci U S A; 1999 Oct; 96(21):11798-803. PubMed ID: 10518530
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional analysis of the nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) enzyme, involved in the late steps of coenzyme B12 biosynthesis in Salmonella enterica.
    Claas KR; Parrish JR; Maggio-Hall LA; Escalante-Semerena JC
    J Bacteriol; 2010 Jan; 192(1):145-54. PubMed ID: 19880598
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Alpha-5,6-dimethylbenzimidazole adenine dinucleotide (alpha-DAD), a putative new intermediate of coenzyme B12 biosynthesis in Salmonella typhimurium.
    Maggio-Hall LA; Escalante-Semerena JC
    Microbiology (Reading); 2003 Apr; 149(Pt 4):983-990. PubMed ID: 12686640
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The three-dimensional structures of nicotinate mononucleotide:5,6- dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella typhimurium complexed with 5,6-dimethybenzimidazole and its reaction products determined to 1.9 A resolution.
    Cheong CG; Escalante-Semerena JC; Rayment I
    Biochemistry; 1999 Dec; 38(49):16125-35. PubMed ID: 10587435
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Purification and characterization of CobT, the nicotinate-mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase enzyme from Salmonella typhimurium LT2.
    Trzebiatowski JR; Escalante-Semerena JC
    J Biol Chem; 1997 Jul; 272(28):17662-7. PubMed ID: 9211916
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Guardian of cobamide diversity: Probing the role of CobT in lower ligand activation in the biosynthesis of vitamin B
    Mathur Y; Vartak AR; Hazra AB
    Methods Enzymol; 2022; 668():25-59. PubMed ID: 35589196
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Capture of a labile substrate by expulsion of water molecules from the active site of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella enterica.
    Cheong CG; Escalante-Semerena JC; Rayment I
    J Biol Chem; 2002 Oct; 277(43):41120-7. PubMed ID: 12101181
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The cobT gene of Salmonella typhimurium encodes the NaMN: 5,6-dimethylbenzimidazole phosphoribosyltransferase responsible for the synthesis of N1-(5-phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole, an intermediate in the synthesis of the nucleotide loop of cobalamin.
    Trzebiatowski JR; O'Toole GA; Escalante-Semerena JC
    J Bacteriol; 1994 Jun; 176(12):3568-75. PubMed ID: 8206834
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A new pathway for the synthesis of α-ribazole-phosphate in Listeria innocua.
    Gray MJ; Escalante-Semerena JC
    Mol Microbiol; 2010 Sep; 77(6):1429-38. PubMed ID: 20633228
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The end of the cob operon: evidence that the last gene (cobT) catalyzes synthesis of the lower ligand of vitamin B12, dimethylbenzimidazole.
    Chen P; Ailion M; Weyand N; Roth J
    J Bacteriol; 1995 Mar; 177(6):1461-9. PubMed ID: 7883701
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cofactor Selectivity in Methylmalonyl Coenzyme A Mutase, a Model Cobamide-Dependent Enzyme.
    Sokolovskaya OM; Mok KC; Park JD; Tran JLA; Quanstrom KA; Taga ME
    mBio; 2019 Sep; 10(5):. PubMed ID: 31551329
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a Novel Cobamide Remodeling Enzyme in the Beneficial Human Gut Bacterium Akkermansia muciniphila.
    Mok KC; Sokolovskaya OM; Nicolas AM; Hallberg ZF; Deutschbauer A; Carlson HK; Taga ME
    mBio; 2020 Dec; 11(6):. PubMed ID: 33293380
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis in Salmonella typhimurium LT2.
    Tsang AW; Escalante-Semerena JC
    J Biol Chem; 1998 Nov; 273(48):31788-94. PubMed ID: 9822644
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.