These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 25421686)

  • 1. Recent progress in the discovery of epigenetic inhibitors for the treatment of cancer.
    Verma SK
    Methods Mol Biol; 2015; 1238():677-88. PubMed ID: 25421686
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of the histone lysine methyltransferase EZH2 for the treatment of cancer.
    Verma SK
    Curr Top Med Chem; 2015; 15(8):714-9. PubMed ID: 25732793
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cancer epigenetics drug discovery and development: the challenge of hitting the mark.
    Campbell RM; Tummino PJ
    J Clin Invest; 2014 Jan; 124(1):64-9. PubMed ID: 24382391
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Recent progress in the discovery of small-molecule inhibitors of the HMT EZH2 for the treatment of cancer.
    Verma SK; Knight SD
    Future Med Chem; 2013 Sep; 5(14):1661-70. PubMed ID: 24047271
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy.
    Morera L; Lübbert M; Jung M
    Clin Epigenetics; 2016; 8():57. PubMed ID: 27222667
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeted epigenetic therapies: the next frontier?
    Tuma RS
    J Natl Cancer Inst; 2010 Dec; 102(24):1824-5. PubMed ID: 21139098
    [No Abstract]   [Full Text] [Related]  

  • 7. Marked for death: targeting epigenetic changes in cancer.
    Pfister SX; Ashworth A
    Nat Rev Drug Discov; 2017 Apr; 16(4):241-263. PubMed ID: 28280262
    [TBL] [Abstract][Full Text] [Related]  

  • 8. EZH2 as a potential target in cancer therapy.
    McCabe MT; Creasy CL
    Epigenomics; 2014 Jun; 6(3):341-51. PubMed ID: 25111487
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Potential Epigenetic Therapy for NSCLC.
    Cancer Discov; 2015 Apr; 5(4):341. PubMed ID: 25724377
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Development of Epigenetics and Related Inhibitors for Targeted Drug Design in Cancer Therapy.
    Liu N; Zhao R; Ma Y; Wang D; Yan C; Zhou D; Yin F; Li Z
    Curr Top Med Chem; 2018; 18(28):2380-2394. PubMed ID: 30430946
    [TBL] [Abstract][Full Text] [Related]  

  • 11. New lysine methyltransferase drug targets in cancer.
    Wagner T; Jung M
    Nat Biotechnol; 2012 Jul; 30(7):622-3. PubMed ID: 22781684
    [No Abstract]   [Full Text] [Related]  

  • 12. Current trends in epigenetic drug discovery.
    Stolfa DA; Einsle O; Sippl W; Jung M
    Future Med Chem; 2012 Oct; 4(16):2029-37. PubMed ID: 23157236
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Epigenetic opportunities and challenges in cancer.
    Best JD; Carey N
    Drug Discov Today; 2010 Jan; 15(1-2):65-70. PubMed ID: 19897050
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Roles of the EZH2 histone methyltransferase in cancer epigenetics.
    Simon JA; Lange CA
    Mutat Res; 2008 Dec; 647(1-2):21-9. PubMed ID: 18723033
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Epigenetic drugs against cancer: an evolving landscape.
    Di Costanzo A; Del Gaudio N; Migliaccio A; Altucci L
    Arch Toxicol; 2014 Sep; 88(9):1651-68. PubMed ID: 25085708
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting histone methyltransferase EZH2 as cancer treatment.
    Kondo Y
    J Biochem; 2014 Nov; 156(5):249-57. PubMed ID: 25179367
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives.
    Andreoli F; Barbosa AJ; Parenti MD; Del Rio A
    Curr Pharm Des; 2013; 19(4):578-613. PubMed ID: 23016851
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Small molecules targeting selected histone methyltransferases (HMTs) for cancer treatment: Current progress and novel strategies.
    Li D; Peng X; Hu Z; Li S; Chen J; Pan W
    Eur J Med Chem; 2024 Jan; 264():115982. PubMed ID: 38056296
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting DNA methylation with small molecules: what's next?
    Erdmann A; Halby L; Fahy J; Arimondo PB
    J Med Chem; 2015 Mar; 58(6):2569-83. PubMed ID: 25406944
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting epigenetic regulators for cancer therapy: modulation of bromodomain proteins, methyltransferases, demethylases, and microRNAs.
    Gelato KA; Adler D; Ocker M; Haendler B
    Expert Opin Ther Targets; 2016 Jul; 20(7):783-99. PubMed ID: 26799480
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.