146 related articles for article (PubMed ID: 25425064)
1. Studies on metabolites and metabolic pathways of bulleyaconitine A in rat liver microsomes using LC-MS(n) combined with specific inhibitors.
Bi Y; Zhuang X; Zhu H; Song F; Liu Z; Liu S
Biomed Chromatogr; 2015 Jul; 29(7):1027-34. PubMed ID: 25425064
[TBL] [Abstract][Full Text] [Related]
2. [Metabolites and metabolic pathways of mesaconitine in rat liver microsomal investigated by using UPLC-MS/MS method in vitro].
Bi YF; Liu S; Zhang RX; Song FR; Liu ZQ
Yao Xue Xue Bao; 2013 Dec; 48(12):1823-8. PubMed ID: 24689241
[TBL] [Abstract][Full Text] [Related]
3. Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine.
Wang Y; Wang S; Liu Y; Yan L; Dou G; Gao Y
J Chromatogr B Analyt Technol Biomed Life Sci; 2006 Dec; 844(2):292-300. PubMed ID: 16949890
[TBL] [Abstract][Full Text] [Related]
4. Characterization of metabolites and human P450 isoforms involved in the microsomal metabolism of mesaconitine.
Ye L; Tang L; Gong Y; Lv C; Zheng Z; Jiang Z; Liu Z
Xenobiotica; 2011 Jan; 41(1):46-58. PubMed ID: 21105783
[TBL] [Abstract][Full Text] [Related]
5. Involvement of CYP3A4/5 and CYP2D6 in the metabolism of aconitine using human liver microsomes and recombinant CYP450 enzymes.
Tang L; Ye L; Lv C; Zheng Z; Gong Y; Liu Z
Toxicol Lett; 2011 Apr; 202(1):47-54. PubMed ID: 21277363
[TBL] [Abstract][Full Text] [Related]
6. Microsomal cytochrome P450-mediated metabolism of hypaconitine, an active and highly toxic constituent derived from Aconitum species.
Ye L; Wang T; Yang C; Tang L; Zhou J; Lv C; Gong Y; Jiang Z; Liu Z
Toxicol Lett; 2011 Jul; 204(1):81-91. PubMed ID: 21550385
[TBL] [Abstract][Full Text] [Related]
7. The exposure of highly toxic aconitine does not significantly impact the activity and expression of cytochrome P450 3A in rats determined by a novel ultra performance liquid chromatography-tandem mass spectrometric method of a specific probe buspirone.
Zhu L; Yang X; Zhou J; Tang L; Xia B; Hu M; Zhou F; Liu Z
Food Chem Toxicol; 2013 Jan; 51():396-403. PubMed ID: 23085095
[TBL] [Abstract][Full Text] [Related]
8. Characterization of in vitro metabolites of TM-2, a potential antitumor drug, in rat, dog and human liver microsomes using liquid chromatography/tandem mass spectrometry.
Men L; Zhao Y; Lin H; Yang M; Liu H; Tang X; Yu Z
Rapid Commun Mass Spectrom; 2014 Oct; 28(20):2162-70. PubMed ID: 25178720
[TBL] [Abstract][Full Text] [Related]
9. Determination of bulleyaconitine A in plasma by a sensitive LC-MS/MS method and its application to an oral pharmacokinetic study in rats.
Wang Q; Tan B; Gong Y; Ji G; Zhang Y; Yang P; Li W; Shen T
J Pharm Biomed Anal; 2012 Dec; 71():202-6. PubMed ID: 22980319
[TBL] [Abstract][Full Text] [Related]
10. New Psychoactive Substances 3-Methoxyphencyclidine (3-MeO-PCP) and 3-Methoxyrolicyclidine (3-MeO-PCPy): Metabolic Fate Elucidated with Rat Urine and Human Liver Preparations and their Detectability in Urine by GC-MS, "LC-(High Resolution)-MSn" and "LC-(High Resolution)-MS/MS".
A Michely JA; Manier SK; Caspar AT; Brandt SD; Wallach J; Maurer HH
Curr Neuropharmacol; 2017; 15(5):692-712. PubMed ID: 27758707
[TBL] [Abstract][Full Text] [Related]
11. Metabolism of sanguinarine in human and in rat: characterization of oxidative metabolites produced by human CYP1A1 and CYP1A2 and rat liver microsomes using liquid chromatography-tandem mass spectrometry.
Deroussent A; RĂ© M; Hoellinger H; Cresteil T
J Pharm Biomed Anal; 2010 Jul; 52(3):391-7. PubMed ID: 19804952
[TBL] [Abstract][Full Text] [Related]
12. Study of in vitro metabolism of m-nisoldipine in human liver microsomes and recombinant cytochrome P450 enzymes by liquid chromatography-mass spectrometry.
Yuan L; Jia P; Sun Y; Zhao C; Zhi X; Sheng N; Zhang L
J Pharm Biomed Anal; 2014 Aug; 97():65-71. PubMed ID: 24816159
[TBL] [Abstract][Full Text] [Related]
13. Comparative metabolism of Lappaconitine in rat and human liver microsomes and in vivo of rat using ultra high-performance liquid chromatography-quadrupole/time-of-flight mass spectrometry.
Yang S; Zhang H; Beier RC; Sun F; Cao X; Shen J; Wang Z; Zhang S
J Pharm Biomed Anal; 2015 Jun; 110():1-11. PubMed ID: 25796978
[TBL] [Abstract][Full Text] [Related]
14. Non-targeted metabolomics-guided sildenafil metabolism study in human liver microsomes.
Kim JH; Jo JH; Seo KA; Hwang H; Lee HS; Lee S
J Chromatogr B Analyt Technol Biomed Life Sci; 2018 Jan; 1072():86-93. PubMed ID: 29136555
[TBL] [Abstract][Full Text] [Related]
15. Metabolism of the new psychoactive substances N,N-diallyltryptamine (DALT) and 5-methoxy-DALT and their detectability in urine by GC-MS, LC-MSn, and LC-HR-MS-MS.
Michely JA; Helfer AG; Brandt SD; Meyer MR; Maurer HH
Anal Bioanal Chem; 2015 Oct; 407(25):7831-42. PubMed ID: 26297461
[TBL] [Abstract][Full Text] [Related]
16. Diphenidine, a new psychoactive substance: metabolic fate elucidated with rat urine and human liver preparations and detectability in urine using GC-MS, LC-MS
Wink CS; Michely JA; Jacobsen-Bauer A; Zapp J; Maurer HH
Drug Test Anal; 2016 Oct; 8(10):1005-1014. PubMed ID: 26811026
[TBL] [Abstract][Full Text] [Related]
17. Metabolism of aildenafil in vivo in rats and in vitro in mouse, rat, dog, and human liver microsomes.
Li Y; Wu L; Gu Y; Si D; Liu C
Drug Test Anal; 2014 Jun; 6(6):552-62. PubMed ID: 24311535
[TBL] [Abstract][Full Text] [Related]
18. Characterization of two phase I metabolites of bendamustine in human liver microsomes and in cancer patients treated with bendamustine hydrochloride.
Teichert J; Baumann F; Chao Q; Franklin C; Bailey B; Hennig L; Caca K; Schoppmeyer K; Patzak U; Preiss R
Cancer Chemother Pharmacol; 2007 May; 59(6):759-70. PubMed ID: 16957931
[TBL] [Abstract][Full Text] [Related]
19. LC-high resolution-MS/MS for identification of 69 metabolites of the new psychoactive substance 1-(4-ethylphenyl-)-N-[(2-methoxyphenyl)methyl] propane-2-amine (4-EA-NBOMe) in rat urine and human liver S9 incubates and comparison of its screening power with further MS techniques.
Caspar AT; Westphal F; Meyer MR; Maurer HH
Anal Bioanal Chem; 2018 Jan; 410(3):897-912. PubMed ID: 28762065
[TBL] [Abstract][Full Text] [Related]
20. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
Yao HT; Wu YS; Chang YW; Hsieh HP; Chen WC; Lan SJ; Chen CT; Chao YS; Chang L; Sun HY; Yeh TK
Drug Metab Dispos; 2007 Jul; 35(7):1042-9. PubMed ID: 17403915
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]