These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

111 related articles for article (PubMed ID: 25426949)

  • 1. Forward genetic screening for regulators involved in cholesterol synthesis using validation-based insertional mutagenesis.
    Jiang W; Tang JJ; Miao HH; Qu YX; Qin J; Xu J; Yang J; Li BL; Song BL
    PLoS One; 2014; 9(11):e112632. PubMed ID: 25426949
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Scavenger receptor CD36 mediates inhibition of cholesterol synthesis via activation of the PPARγ/PGC-1α pathway and Insig1/2 expression in hepatocytes.
    Rodrigue-Way A; Caron V; Bilodeau S; Keil S; Hassan M; Lévy E; Mitchell GA; Tremblay A
    FASEB J; 2014 Apr; 28(4):1910-23. PubMed ID: 24371122
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SCAP/SREBP pathway is required for the full steroidogenic response to cyclic AMP.
    Shimizu-Albergine M; Van Yserloo B; Golkowski MG; Ong SE; Beavo JA; Bornfeldt KE
    Proc Natl Acad Sci U S A; 2016 Sep; 113(38):E5685-93. PubMed ID: 27601673
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells.
    Lee PC; DeBose-Boyd RA
    J Lipid Res; 2010 Jan; 51(1):192-201. PubMed ID: 19617589
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cross-talk between TLR4-MyD88-NF-κB and SCAP-SREBP2 pathways mediates macrophage foam cell formation.
    Li LC; Varghese Z; Moorhead JF; Lee CT; Chen JB; Ruan XZ
    Am J Physiol Heart Circ Physiol; 2013 Mar; 304(6):H874-84. PubMed ID: 23335792
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rapamycin down-regulates LDL-receptor expression independently of SREBP-2.
    Sharpe LJ; Brown AJ
    Biochem Biophys Res Commun; 2008 Sep; 373(4):670-4. PubMed ID: 18602894
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Polyphenol-rich black chokeberry (Aronia melanocarpa) extract regulates the expression of genes critical for intestinal cholesterol flux in Caco-2 cells.
    Kim B; Park Y; Wegner CJ; Bolling BW; Lee J
    J Nutr Biochem; 2013 Sep; 24(9):1564-70. PubMed ID: 23517916
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74 Int cells.
    Jesch ED; Seo JM; Carr TP; Lee JY
    Nutr Res; 2009 Dec; 29(12):859-66. PubMed ID: 19963159
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ring finger protein 5 activates sterol regulatory element-binding protein 2 (SREBP2) to promote cholesterol biosynthesis via inducing polyubiquitination of SREBP chaperone SCAP.
    Kuan YC; Takahashi Y; Maruyama T; Shimizu M; Yamauchi Y; Sato R
    J Biol Chem; 2020 Mar; 295(12):3918-3928. PubMed ID: 32054686
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual functions of Insig proteins in cholesterol homeostasis.
    Dong XY; Tang SQ; Chen JD
    Lipids Health Dis; 2012 Dec; 11():173. PubMed ID: 23249523
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Overexpression of A-kinase anchoring protein 12A activates sterol regulatory element binding protein-2 and enhances cholesterol efflux in hepatic cells.
    Choi MC; Lee YU; Kim SH; Lee JH; Park JH; Streb JW; Oh DY; Im SA; Kim TY; Jong HS; Bang YJ
    Int J Biochem Cell Biol; 2008; 40(11):2534-43. PubMed ID: 18579430
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitochondrial aquaporin-8 is involved in SREBP-controlled hepatocyte cholesterol biosynthesis.
    Danielli M; Marrone J; Capiglioni AM; Marinelli RA
    Free Radic Biol Med; 2019 Feb; 131():370-375. PubMed ID: 30579780
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inflammatory stress induces statin resistance by disrupting 3-hydroxy-3-methylglutaryl-CoA reductase feedback regulation.
    Chen Y; Ku H; Zhao L; Wheeler DC; Li LC; Li Q; Varghese Z; Moorhead JF; Powis SH; Huang A; Ruan XZ
    Arterioscler Thromb Vasc Biol; 2014 Feb; 34(2):365-76. PubMed ID: 24233489
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Akt acutely activates the cholesterogenic transcription factor SREBP-2.
    Luu W; Sharpe LJ; Stevenson J; Brown AJ
    Biochim Biophys Acta; 2012 Feb; 1823(2):458-64. PubMed ID: 22005015
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overexpression of a key regulator of lipid homeostasis, Scap, promotes respiration in prostate cancer cells.
    Prabhu AV; Krycer JR; Brown AJ
    FEBS Lett; 2013 Apr; 587(7):983-8. PubMed ID: 23454642
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase during high fat diet feeding.
    Wu N; Sarna LK; Hwang SY; Zhu Q; Wang P; Siow YL; O K
    Biochim Biophys Acta; 2013 Oct; 1832(10):1560-8. PubMed ID: 23651731
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quercetin 3-glucoside protects neuroblastoma (SH-SY5Y) cells in vitro against oxidative damage by inducing sterol regulatory element-binding protein-2-mediated cholesterol biosynthesis.
    Soundararajan R; Wishart AD; Rupasinghe HP; Arcellana-Panlilio M; Nelson CM; Mayne M; Robertson GS
    J Biol Chem; 2008 Jan; 283(4):2231-45. PubMed ID: 18032389
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of novel regulatory cholesterol metabolite, 5-cholesten, 3β,25-diol, disulfate.
    Ren S; Kim JK; Kakiyama G; Rodriguez-Agudo D; Pandak WM; Min HK; Ning Y
    PLoS One; 2014; 9(7):e103621. PubMed ID: 25072708
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of human 3-hydroxy-3-methylglutaryl CoA reductase by peptides leading to cholesterol homeostasis through SREBP2 pathway in HepG2 cells.
    Kumar V; Sharma P; Bairagya HR; Sharma S; Singh TP; Tiku PK
    Biochim Biophys Acta Proteins Proteom; 2019 Jun; 1867(6):604-615. PubMed ID: 30954578
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Caloric restrictions affect some factors involved in age-related hypercholesterolemia.
    Martini C; Pallottini V; Cavallini G; Donati A; Bergamini E; Trentalance A
    J Cell Biochem; 2007 May; 101(1):235-43. PubMed ID: 17203467
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.