428 related articles for article (PubMed ID: 25437617)
1. Hydroxylated 2,4-diphenyl indenopyridine derivatives as a selective non-intercalative topoisomerase IIα catalytic inhibitor.
Kadayat TM; Park C; Jun KY; Thapa Magar TB; Bist G; Yoo HY; Kwon Y; Lee ES
Eur J Med Chem; 2015 Jan; 90():302-14. PubMed ID: 25437617
[TBL] [Abstract][Full Text] [Related]
2. Dihydroxylated 2,6-diphenyl-4-chlorophenylpyridines: Topoisomerase I and IIα dual inhibitors with DNA non-intercalative catalytic activity.
Bist G; Park S; Song C; Thapa Magar TB; Shrestha A; Kwon Y; Lee ES
Eur J Med Chem; 2017 Jun; 133():69-84. PubMed ID: 28384547
[TBL] [Abstract][Full Text] [Related]
3. 4-Flourophenyl-substituted 5H-indeno[1,2-b]pyridinols with enhanced topoisomerase IIα inhibitory activity: Synthesis, biological evaluation, and structure-activity relationships.
Kunwar S; Hwang SY; Katila P; Seo M; Man Kadayat T; Kwon Y; Lee ES
Bioorg Chem; 2021 Nov; 116():105349. PubMed ID: 34536927
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological activity of 2,4-di-p-phenolyl-6-2-furanyl-pyridine as a potent topoisomerase II poison.
Karki R; Park C; Jun KY; Kadayat TM; Lee ES; Kwon Y
Eur J Med Chem; 2015 Jan; 90():360-78. PubMed ID: 25437622
[TBL] [Abstract][Full Text] [Related]
5. Novel 2-aryl-4-(4'-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors.
Park S; Kadayat TM; Jun KY; Thapa Magar TB; Bist G; Shrestha A; Lee ES; Kwon Y
Eur J Med Chem; 2017 Jan; 125():14-28. PubMed ID: 27643560
[TBL] [Abstract][Full Text] [Related]
6. 3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage.
Park SE; Chang IH; Jun KY; Lee E; Lee ES; Na Y; Kwon Y
Eur J Med Chem; 2013 Nov; 69():139-45. PubMed ID: 24013413
[TBL] [Abstract][Full Text] [Related]
7. Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines.
Kadayat TM; Song C; Shin S; Magar TB; Bist G; Shrestha A; Thapa P; Na Y; Kwon Y; Lee ES
Bioorg Med Chem; 2015 Jul; 23(13):3499-512. PubMed ID: 26022080
[TBL] [Abstract][Full Text] [Related]
8. Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic topoisomerase I and II dual inhibitor.
Park S; Thapa Magar TB; Kadayat TM; Lee HJ; Bist G; Shrestha A; Lee ES; Kwon Y
Eur J Med Chem; 2017 Feb; 127():318-333. PubMed ID: 28068603
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor.
Jun KY; Lee EY; Jung MJ; Lee OH; Lee ES; Park Choo HY; Na Y; Kwon Y
Eur J Med Chem; 2011 Jun; 46(6):1964-71. PubMed ID: 21419530
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure-activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor.
Ahmad P; Woo H; Jun KY; Kadi AA; Abdel-Aziz HA; Kwon Y; Rahman AF
Bioorg Med Chem; 2016 Apr; 24(8):1898-908. PubMed ID: 26988802
[TBL] [Abstract][Full Text] [Related]
11. Topoisomerase IIα inhibitory and antiproliferative activity of dihydroxylated 2,6-diphenyl-4-fluorophenylpyridines: Design, synthesis, and structure-activity relationships.
Kunwar S; Hwang SY; Katila P; Man Kadayat T; Jung AR; Kwon Y; Lee ES
Bioorg Med Chem Lett; 2022 Mar; 60():128606. PubMed ID: 35123005
[TBL] [Abstract][Full Text] [Related]
12. Discovery of a 2,4-diphenyl-5,6-dihydrobenzo(h)quinolin-8-amine derivative as a novel DNA intercalating topoisomerase IIα poison.
Kunwar S; Hwang SY; Katila P; Park S; Jeon KH; Kim D; Kadayat TM; Kwon Y; Lee ES
Eur J Med Chem; 2021 Dec; 226():113860. PubMed ID: 34597897
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and SAR study of new hydroxy and chloro-substituted 2,4-diphenyl 5H-chromeno[4,3-b]pyridines as selective topoisomerase IIα-targeting anticancer agents.
Magar TBT; Seo SH; Kadayat TM; Jo H; Shrestha A; Bist G; Katila P; Kwon Y; Lee ES
Bioorg Med Chem; 2018 May; 26(8):1909-1919. PubMed ID: 29510948
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, antitumor activity, and structure-activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors.
Karki R; Park C; Jun KY; Jee JG; Lee JH; Thapa P; Kadayat TM; Kwon Y; Lee ES
Eur J Med Chem; 2014 Sep; 84():555-65. PubMed ID: 25062006
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and structure-activity relationships of hydroxylated and halogenated 2,4-diaryl benzofuro[3,2-b]pyridin-7-ols as selective topoisomerase IIα inhibitors.
Thapa Magar TB; Hee Seo S; Shrestha A; Kim JA; Kunwar S; Bist G; Kwon Y; Lee ES
Bioorg Chem; 2021 Jun; 111():104884. PubMed ID: 33872925
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, biological evaluation, structure-activity relationship study, and mode of action of 2-phenol-4,6-dichlorophenyl-pyridines.
Shrestha A; Park S; Shin S; Man Kadayat T; Bist G; Katila P; Kwon Y; Lee ES
Bioorg Chem; 2018 Sep; 79():1-18. PubMed ID: 29715635
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of N-(carbobenzyloxy)-l-phenylalanine and N-(carbobenzyloxy)-l-aspartic acid-β-benzyl ester derivatives as potent topoisomerase IIα inhibitors.
Han X; Zhong Y; Zhou G; Qi H; Li S; Ding Q; Liu Z; Song Y; Qiao X
Bioorg Med Chem; 2017 Jun; 25(12):3116-3126. PubMed ID: 28462840
[TBL] [Abstract][Full Text] [Related]
18. Design and synthesis of conformationally constrained hydroxylated 4-phenyl-2-aryl chromenopyridines as novel and selective topoisomerase II-targeted antiproliferative agents.
Thapa P; Jun KY; Kadayat TM; Park C; Zheng Z; Thapa Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
Bioorg Med Chem; 2015 Oct; 23(19):6454-66. PubMed ID: 26361737
[TBL] [Abstract][Full Text] [Related]
19. Topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of dihydroxylated 2,6-diphenyl-4-aryl pyridines.
Karki R; Song C; Kadayat TM; Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
Bioorg Med Chem; 2015 Jul; 23(13):3638-54. PubMed ID: 25936262
[TBL] [Abstract][Full Text] [Related]
20. Discovery of dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitor.
Jun KY; Kwon H; Park SE; Lee E; Karki R; Thapa P; Lee JH; Lee ES; Kwon Y
Eur J Med Chem; 2014 Jun; 80():428-38. PubMed ID: 24796883
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
