BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 25444914)

  • 1. Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells.
    Li X; Zhu F; Jiang J; Sun C; Wang X; Shen M; Tian R; Shi C; Xu M; Peng F; Guo X; Wang M; Qin R
    Cancer Lett; 2015 Feb; 357(1):219-230. PubMed ID: 25444914
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of PI3K/AKT signaling via ROS regulation is involved in Rhein-induced apoptosis and enhancement of oxaliplatin sensitivity in pancreatic cancer cells.
    Liu Y; Shi C; He Z; Zhu F; Wang M; He R; Zhao C; Shi X; Zhou M; Pan S; Gao Y; Li X; Qin R
    Int J Biol Sci; 2021; 17(2):589-602. PubMed ID: 33613115
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oxymatrine synergistically enhances antitumor activity of oxaliplatin in colon carcinoma through PI3K/AKT/mTOR pathway.
    Liu Y; Bi T; Wang Z; Wu G; Qian L; Gao Q; Shen G
    Apoptosis; 2016 Dec; 21(12):1398-1407. PubMed ID: 27671687
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Different effects of 4β-hydroxywithanolide E and withaferin A, two withanolides from Solanaceae plants, on the Akt signaling pathway in human breast cancer cells.
    Wang HC; Hu HH; Chang FR; Tsai JY; Kuo CY; Wu YC; Wu CC
    Phytomedicine; 2019 Feb; 53():213-222. PubMed ID: 30668401
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protection against cerebral infarction by Withaferin A involves inhibition of neuronal apoptosis, activation of PI3K/Akt signaling pathway, and reduced intimal hyperplasia via inhibition of VSMC migration and matrix metalloproteinases.
    Zhang QZ; Guo YD; Li HM; Wang RZ; Guo SG; Du YF
    Adv Med Sci; 2017 Mar; 62(1):186-192. PubMed ID: 28282606
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Withaferin A, a natural thioredoxin reductase 1 (TrxR1) inhibitor, synergistically enhances the antitumor efficacy of sorafenib through ROS-mediated ER stress and DNA damage in hepatocellular carcinoma cells.
    Chen X; Zhu N; Wu Y; Zhang Y; Zhang Y; Jin K; Zhou Z; Chen G; Wang J
    Phytomedicine; 2024 Jun; 128():155317. PubMed ID: 38537439
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Withaferin A induces apoptosis by ROS-dependent mitochondrial dysfunction in human colorectal cancer cells.
    Xia S; Miao Y; Liu S
    Biochem Biophys Res Commun; 2018 Sep; 503(4):2363-2369. PubMed ID: 29966656
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metformin combined with quercetin synergistically repressed prostate cancer cells via inhibition of VEGF/PI3K/Akt signaling pathway.
    Sun S; Gong F; Liu P; Miao Q
    Gene; 2018 Jul; 664():50-57. PubMed ID: 29678660
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting the Janus-activated kinase-2-STAT3 signalling pathway in pancreatic cancer using the HSP90 inhibitor ganetespib.
    Nagaraju GP; Mezina A; Shaib WL; Landry J; El-Rayes BF
    Eur J Cancer; 2016 Jan; 52():109-19. PubMed ID: 26682870
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Zoledronic Acid Enhanced the Antitumor Effect of Cisplatin on Orthotopic Osteosarcoma by ROS-PI3K/AKT Signaling and Attenuated Osteolysis.
    Liu L; Geng H; Mei C; Chen L
    Oxid Med Cell Longev; 2021; 2021():6661534. PubMed ID: 33859780
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Withaferin A-caused production of intracellular reactive oxygen species modulates apoptosis via PI3K/Akt and JNKinase in rabbit articular chondrocytes.
    Yu SM; Kim SJ
    J Korean Med Sci; 2014 Aug; 29(8):1042-53. PubMed ID: 25120312
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modulating effect of the PI3-kinase inhibitor LY294002 on cisplatin in human pancreatic cancer cells.
    Fujiwara M; Izuishi K; Sano T; Hossain MA; Kimura S; Masaki T; Suzuki Y
    J Exp Clin Cancer Res; 2008 Nov; 27(1):76. PubMed ID: 19032736
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway.
    Wang SQ; Wang C; Chang LM; Zhou KR; Wang JW; Ke Y; Yang DX; Shi HG; Wang R; Shi XL; Ma LY; Liu HM
    Oncotarget; 2016 Nov; 7(45):72990-73002. PubMed ID: 27659528
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phytochemicals, withaferin A and carnosol, overcome pancreatic cancer stem cells as c-Met inhibitors.
    Aliebrahimi S; Kouhsari SM; Arab SS; Shadboorestan A; Ostad SN
    Biomed Pharmacother; 2018 Oct; 106():1527-1536. PubMed ID: 30119228
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Withaferin A enhances radiation-induced apoptosis in Caki cells through induction of reactive oxygen species, Bcl-2 downregulation and Akt inhibition.
    Yang ES; Choi MJ; Kim JH; Choi KS; Kwon TK
    Chem Biol Interact; 2011 Mar; 190(1):9-15. PubMed ID: 21256832
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress.
    Kopetz S; Lesslie DP; Dallas NA; Park SI; Johnson M; Parikh NU; Kim MP; Abbruzzese JL; Ellis LM; Chandra J; Gallick GE
    Cancer Res; 2009 May; 69(9):3842-9. PubMed ID: 19383922
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Amiloride sensitizes human pancreatic cancer cells to erlotinib in vitro through inhibition of the PI3K/AKT signaling pathway.
    Zheng YT; Yang HY; Li T; Zhao B; Shao TF; Xiang XQ; Cai WM
    Acta Pharmacol Sin; 2015 May; 36(5):614-26. PubMed ID: 25864651
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular mechanisms of hyperthermia-induced apoptosis enhanced by withaferin A.
    Cui ZG; Piao JL; Rehman MU; Ogawa R; Li P; Zhao QL; Kondo T; Inadera H
    Eur J Pharmacol; 2014 Jan; 723():99-107. PubMed ID: 24321857
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stellettin B induces apoptosis in human chronic myeloid leukemia cells via targeting PI3K and Stat5.
    Chen Y; Zhou Q; Zhang L; Zhong Y; Fan G; Zhang Z; Wang R; Jin M; Qiu Y; Kong D
    Oncotarget; 2017 Apr; 8(17):28906-28921. PubMed ID: 28423649
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells.
    Suman S; Das TP; Sirimulla S; Alatassi H; Ankem MK; Damodaran C
    Oncotarget; 2016 Mar; 7(12):13854-64. PubMed ID: 26883103
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.