132 related articles for article (PubMed ID: 25445676)
1. Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter.
Gál Z; Hegedüs C; Szakács G; Váradi A; Sarkadi B; Özvegy-Laczka C
Biochim Biophys Acta; 2015 Feb; 1848(2):477-87. PubMed ID: 25445676
[TBL] [Abstract][Full Text] [Related]
2. Regulation of the function of the human ABCG2 multidrug transporter by cholesterol and bile acids: effects of mutations in potential substrate and steroid binding sites.
Telbisz Á; Hegedüs C; Váradi A; Sarkadi B; Özvegy-Laczka C
Drug Metab Dispos; 2014 Apr; 42(4):575-85. PubMed ID: 24384916
[TBL] [Abstract][Full Text] [Related]
3. Effects of the lipid environment, cholesterol and bile acids on the function of the purified and reconstituted human ABCG2 protein.
Telbisz Á; Özvegy-Laczka C; Hegedűs T; Váradi A; Sarkadi B
Biochem J; 2013 Mar; 450(2):387-95. PubMed ID: 23205634
[TBL] [Abstract][Full Text] [Related]
4. Membrane cholesterol selectively modulates the activity of the human ABCG2 multidrug transporter.
Telbisz A; Müller M; Ozvegy-Laczka C; Homolya L; Szente L; Váradi A; Sarkadi B
Biochim Biophys Acta; 2007 Nov; 1768(11):2698-713. PubMed ID: 17662239
[TBL] [Abstract][Full Text] [Related]
5. Effects of the gout-causing Q141K polymorphism and a CFTR ΔF508 mimicking mutation on the processing and stability of the ABCG2 protein.
Sarankó H; Tordai H; Telbisz Á; Özvegy-Laczka C; Erdős G; Sarkadi B; Hegedűs T
Biochem Biophys Res Commun; 2013 Jul; 437(1):140-5. PubMed ID: 23800412
[TBL] [Abstract][Full Text] [Related]
6. Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition.
Ozvegy-Laczka C; Köblös G; Sarkadi B; Váradi A
Biochim Biophys Acta; 2005 Feb; 1668(1):53-63. PubMed ID: 15670731
[TBL] [Abstract][Full Text] [Related]
7. Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation.
Ozvegy C; Váradi A; Sarkadi B
J Biol Chem; 2002 Dec; 277(50):47980-90. PubMed ID: 12374800
[TBL] [Abstract][Full Text] [Related]
8. Mutational analysis of ABCG2: role of the GXXXG motif.
Polgar O; Robey RW; Morisaki K; Dean M; Michejda C; Sauna ZE; Ambudkar SV; Tarasova N; Bates SE
Biochemistry; 2004 Jul; 43(29):9448-56. PubMed ID: 15260487
[TBL] [Abstract][Full Text] [Related]
9. Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells.
Ozvegy C; Litman T; Szakács G; Nagy Z; Bates S; Váradi A; Sarkadi B
Biochem Biophys Res Commun; 2001 Jul; 285(1):111-7. PubMed ID: 11437380
[TBL] [Abstract][Full Text] [Related]
10. Oligomerization of the human ABC transporter ABCG2: evaluation of the native protein and chimeric dimers.
Bhatia A; Schäfer HJ; Hrycyna CA
Biochemistry; 2005 Aug; 44(32):10893-904. PubMed ID: 16086592
[TBL] [Abstract][Full Text] [Related]
11. Cholesterol potentiates ABCG2 activity in a heterologous expression system: improved in vitro model to study function of human ABCG2.
Pál A; Méhn D; Molnár E; Gedey S; Mészáros P; Nagy T; Glavinas H; Janáky T; von Richter O; Báthori G; Szente L; Krajcsi P
J Pharmacol Exp Ther; 2007 Jun; 321(3):1085-94. PubMed ID: 17347325
[TBL] [Abstract][Full Text] [Related]
12. The nature of amino acid 482 of human ABCG2 affects substrate transport and ATP hydrolysis but not substrate binding.
Ejendal KF; Diop NK; Schweiger LC; Hrycyna CA
Protein Sci; 2006 Jul; 15(7):1597-607. PubMed ID: 16815914
[TBL] [Abstract][Full Text] [Related]
13. Mutational studies of G553 in TM5 of ABCG2: a residue potentially involved in dimerization.
Polgar O; Ozvegy-Laczka C; Robey RW; Morisaki K; Okada M; Tamaki A; Koblos G; Elkind NB; Ward Y; Dean M; Sarkadi B; Bates SE
Biochemistry; 2006 Apr; 45(16):5251-60. PubMed ID: 16618113
[TBL] [Abstract][Full Text] [Related]
14. Single nucleotide polymorphisms result in impaired membrane localization and reduced atpase activity in multidrug transporter ABCG2.
Mizuarai S; Aozasa N; Kotani H
Int J Cancer; 2004 Mar; 109(2):238-46. PubMed ID: 14750175
[TBL] [Abstract][Full Text] [Related]
15. Cholesterol sensing by the ABCG1 lipid transporter: Requirement of a CRAC motif in the final transmembrane domain.
Sharpe LJ; Rao G; Jones PM; Glancey E; Aleidi SM; George AM; Brown AJ; Gelissen IC
Biochim Biophys Acta; 2015 Jul; 1851(7):956-64. PubMed ID: 25732853
[TBL] [Abstract][Full Text] [Related]
16. N-Linked glycosylation of the human ABC transporter ABCG2 on asparagine 596 is not essential for expression, transport activity, or trafficking to the plasma membrane.
Diop NK; Hrycyna CA
Biochemistry; 2005 Apr; 44(14):5420-9. PubMed ID: 15807535
[TBL] [Abstract][Full Text] [Related]
17. Structure of the Human Cholesterol Transporter ABCG1.
Skarda L; Kowal J; Locher KP
J Mol Biol; 2021 Oct; 433(21):167218. PubMed ID: 34461069
[TBL] [Abstract][Full Text] [Related]
18. Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in transmembrane segment 1 of ABCG2.
Polgar O; Ierano C; Tamaki A; Stanley B; Ward Y; Xia D; Tarasova N; Robey RW; Bates SE
Biochemistry; 2010 Mar; 49(10):2235-45. PubMed ID: 20088606
[TBL] [Abstract][Full Text] [Related]
19. Identification of cysteine residues critically involved in homodimer formation and protein expression of human ATP-binding cassette transporter ABCG2: a new approach using the flp recombinase system.
Wakabayashi K; Nakagawa H; Adachi T; Kii I; Kobatake E; Kudo A; Ishikawa T
J Exp Ther Oncol; 2006; 5(3):205-22. PubMed ID: 16528971
[TBL] [Abstract][Full Text] [Related]
20. Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2.
Henriksen U; Gether U; Litman T
J Cell Sci; 2005 Apr; 118(Pt 7):1417-26. PubMed ID: 15769853
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
