BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

595 related articles for article (PubMed ID: 25446254)

  • 1. TRAIL activates JNK and NF-κB through RIP1-dependent and -independent pathways.
    Zhang L; Dittmer MR; Blackwell K; Workman LM; Hostager B; Habelhah H
    Cell Signal; 2015 Feb; 27(2):306-14. PubMed ID: 25446254
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RIP1 Cleavage in the Kinase Domain Regulates TRAIL-Induced NF-κB Activation and Lymphoma Survival.
    Zhang L; Blackwell K; Workman LM; Chen S; Pope MR; Janz S; Habelhah H
    Mol Cell Biol; 2015 Oct; 35(19):3324-38. PubMed ID: 26195820
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NF-kappaB inhibition reveals differential mechanisms of TNF versus TRAIL-induced apoptosis upstream or at the level of caspase-8 activation independent of cIAP2.
    Diessenbacher P; Hupe M; Sprick MR; Kerstan A; Geserick P; Haas TL; Wachter T; Neumann M; Walczak H; Silke J; Leverkus M
    J Invest Dermatol; 2008 May; 128(5):1134-47. PubMed ID: 17989734
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MAPK p38 and JNK have opposing activities on TRAIL-induced apoptosis activation in NSCLC H460 cells that involves RIP1 and caspase-8 and is mediated by Mcl-1.
    Azijli K; Yuvaraj S; van Roosmalen I; Flach K; Giovannetti E; Peters GJ; de Jong S; Kruyt FA
    Apoptosis; 2013 Jul; 18(7):851-60. PubMed ID: 23456625
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The involvement of β-actin in the signaling of transmembrane TNF-α-mediated cytotoxicity.
    Chen H; Xiao L; Zhang H; Liu N; Liu T; Liu L; Hu X; Yan D; Yang K; Yin B; Wang J; Li Q; Li Z
    J Leukoc Biol; 2011 Jun; 89(6):917-26. PubMed ID: 21402772
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ubiquitination profiling identifies sensitivity factors for IAP antagonist treatment.
    Varfolomeev E; Izrael-Tomasevic A; Yu K; Bustos D; Goncharov T; Belmont LD; Masselot A; Bakalarski CE; Kirkpatrick DS; Vucic D
    Biochem J; 2015 Feb; 466(1):45-54. PubMed ID: 25423073
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TNFR1 signaling kinetics: spatiotemporal control of three phases of IKK activation by posttranslational modification.
    Workman LM; Habelhah H
    Cell Signal; 2013 Aug; 25(8):1654-64. PubMed ID: 23612498
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinct Activation Mechanisms of NF-κB Regulator Inhibitor of NF-κB Kinase (IKK) by Isoforms of the Cell Death Regulator Cellular FLICE-like Inhibitory Protein (cFLIP).
    Baratchian M; Davis CA; Shimizu A; Escors D; Bagnéris C; Barrett T; Collins MK
    J Biol Chem; 2016 Apr; 291(14):7608-20. PubMed ID: 26865630
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IRF-1 inhibits NF-κB activity, suppresses TRAF2 and cIAP1 and induces breast cancer cell specific growth inhibition.
    Armstrong MJ; Stang MT; Liu Y; Yan J; Pizzoferrato E; Yim JH
    Cancer Biol Ther; 2015; 16(7):1029-41. PubMed ID: 26011589
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The C-terminal domain of the long form of cellular FLICE-inhibitory protein (c-FLIPL) inhibits the interaction of the caspase 8 prodomain with the receptor-interacting protein 1 (RIP1) death domain and regulates caspase 8-dependent nuclear factor κB (NF-κB) activation.
    Matsuda I; Matsuo K; Matsushita Y; Haruna Y; Niwa M; Kataoka T
    J Biol Chem; 2014 Feb; 289(7):3876-87. PubMed ID: 24398693
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RIP1 is required for IAP inhibitor-mediated sensitization for TRAIL-induced apoptosis via a RIP1/FADD/caspase-8 cell death complex.
    Abhari BA; Cristofanon S; Kappler R; von Schweinitz D; Humphreys R; Fulda S
    Oncogene; 2013 Jul; 32(27):3263-73. PubMed ID: 22890322
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed IκB kinase activation.
    Blackwell K; Zhang L; Workman LM; Ting AT; Iwai K; Habelhah H
    Mol Cell Biol; 2013 May; 33(10):1901-15. PubMed ID: 23459942
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells.
    Kim YS; Schwabe RF; Qian T; Lemasters JJ; Brenner DA
    Hepatology; 2002 Dec; 36(6):1498-508. PubMed ID: 12447876
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways.
    Hu WH; Johnson H; Shu HB
    J Biol Chem; 1999 Oct; 274(43):30603-10. PubMed ID: 10521444
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Smac mimetic sensitizes glioblastoma cells to Temozolomide-induced apoptosis in a RIP1- and NF-κB-dependent manner.
    Wagner L; Marschall V; Karl S; Cristofanon S; Zobel K; Deshayes K; Vucic D; Debatin KM; Fulda S
    Oncogene; 2013 Feb; 32(8):988-97. PubMed ID: 22469979
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination.
    de Almagro MC; Goncharov T; Newton K; Vucic D
    Cell Death Dis; 2015 Jun; 6(6):e1800. PubMed ID: 26111062
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling.
    Kreuz S; Siegmund D; Scheurich P; Wajant H
    Mol Cell Biol; 2001 Jun; 21(12):3964-73. PubMed ID: 11359904
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Y14 positively regulates TNF-α-induced NF-κB transcriptional activity via interacting RIP1 and TRADD beyond an exon junction complex protein.
    Togi S; Shiga K; Muromoto R; Kato M; Souma Y; Sekine Y; Kon S; Oritani K; Matsuda T
    J Immunol; 2013 Aug; 191(3):1436-44. PubMed ID: 23817415
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Xenopus death-domain-containing proteins FADD and RIP1 synergistically activate JNK and NF-kappaB.
    Ishizawa YH; Tamura K; Yamaguchi T; Matsumoto K; Komiyama M; Takamatsu N; Shiba T; Ito M
    Biol Cell; 2006 Aug; 98(8):465-78. PubMed ID: 16597320
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TRAF2 phosphorylation promotes NF-κB-dependent gene expression and inhibits oxidative stress-induced cell death.
    Zhang L; Blackwell K; Altaeva A; Shi Z; Habelhah H
    Mol Biol Cell; 2011 Jan; 22(1):128-40. PubMed ID: 21119000
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.