These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

371 related articles for article (PubMed ID: 25447237)

  • 1. Nuclear import factor transportin and arginine methyltransferase 1 modify FUS neurotoxicity in Drosophila.
    Jäckel S; Summerer AK; Thömmes CM; Pan X; Voigt A; Schulz JB; Rasse TM; Dormann D; Haass C; Kahle PJ
    Neurobiol Dis; 2015 Feb; 74():76-88. PubMed ID: 25447237
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS.
    Xia R; Liu Y; Yang L; Gal J; Zhu H; Jia J
    Mol Neurodegener; 2012 Mar; 7():10. PubMed ID: 22443542
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of ter94, Drosophila VCP, as a strong modulator of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS.
    Azuma Y; Tokuda T; Shimamura M; Kyotani A; Sasayama H; Yoshida T; Mizuta I; Mizuno T; Nakagawa M; Fujikake N; Ueyama M; Nagai Y; Yamaguchi M
    Hum Mol Genet; 2014 Jul; 23(13):3467-80. PubMed ID: 24497576
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The ALS gene FUS regulates synaptic transmission at the Drosophila neuromuscular junction.
    Machamer JB; Collins SE; Lloyd TE
    Hum Mol Genet; 2014 Jul; 23(14):3810-22. PubMed ID: 24569165
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS.
    Dormann D; Madl T; Valori CF; Bentmann E; Tahirovic S; Abou-Ajram C; Kremmer E; Ansorge O; Mackenzie IR; Neumann M; Haass C
    EMBO J; 2012 Nov; 31(22):4258-75. PubMed ID: 22968170
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genetic link between Cabeza, a Drosophila homologue of Fused in Sarcoma (FUS), and the EGFR signaling pathway.
    Shimamura M; Kyotani A; Azuma Y; Yoshida H; Binh Nguyen T; Mizuta I; Yoshida T; Mizuno T; Nakagawa M; Tokuda T; Yamaguchi M
    Exp Cell Res; 2014 Aug; 326(1):36-45. PubMed ID: 24928275
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hippo, Drosophila MST, is a novel modifier of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS.
    Azuma Y; Tokuda T; Kushimura Y; Yamamoto I; Mizuta I; Mizuno T; Nakagawa M; Ueyama M; Nagai Y; Iwasaki Y; Yoshida M; Pan D; Yoshida H; Yamaguchi M
    Exp Cell Res; 2018 Oct; 371(2):311-321. PubMed ID: 30092221
    [TBL] [Abstract][Full Text] [Related]  

  • 8.
    Mallik M; Catinozzi M; Hug CB; Zhang L; Wagner M; Bussmann J; Bittern J; Mersmann S; Klämbt C; Drexler HCA; Huynen MA; Vaquerizas JM; Storkebaum E
    J Cell Biol; 2018 Nov; 217(11):3947-3964. PubMed ID: 30209068
    [No Abstract]   [Full Text] [Related]  

  • 9. Mechanism of karyopherin-β2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).
    Gonzalez A; Mannen T; Çağatay T; Fujiwara A; Matsumura H; Niesman AB; Brautigam CA; Chook YM; Yoshizawa T
    Sci Rep; 2021 Feb; 11(1):3754. PubMed ID: 33580145
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FUS causes synaptic hyperexcitability in Drosophila dendritic arborization neurons.
    Machamer JB; Woolums BM; Fuller GG; Lloyd TE
    Brain Res; 2018 Aug; 1693(Pt A):55-66. PubMed ID: 29625118
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Knockdown of the Drosophila fused in sarcoma (FUS) homologue causes deficient locomotive behavior and shortening of motoneuron terminal branches.
    Sasayama H; Shimamura M; Tokuda T; Azuma Y; Yoshida T; Mizuno T; Nakagawa M; Fujikake N; Nagai Y; Yamaguchi M
    PLoS One; 2012; 7(6):e39483. PubMed ID: 22724023
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.
    Dormann D; Rodde R; Edbauer D; Bentmann E; Fischer I; Hruscha A; Than ME; Mackenzie IR; Capell A; Schmid B; Neumann M; Haass C
    EMBO J; 2010 Aug; 29(16):2841-57. PubMed ID: 20606625
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo.
    Scaramuzzino C; Monaghan J; Milioto C; Lanson NA; Maltare A; Aggarwal T; Casci I; Fackelmayer FO; Pennuto M; Pandey UB
    PLoS One; 2013; 8(4):e61576. PubMed ID: 23620769
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
    Hofweber M; Hutten S; Bourgeois B; Spreitzer E; Niedner-Boblenz A; Schifferer M; Ruepp MD; Simons M; Niessing D; Madl T; Dormann D
    Cell; 2018 Apr; 173(3):706-719.e13. PubMed ID: 29677514
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS).
    Zhang ZC; Chook YM
    Proc Natl Acad Sci U S A; 2012 Jul; 109(30):12017-21. PubMed ID: 22778397
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.
    Neumann M; Valori CF; Ansorge O; Kretzschmar HA; Munoz DG; Kusaka H; Yokota O; Ishihara K; Ang LC; Bilbao JM; Mackenzie IR
    Acta Neuropathol; 2012 Nov; 124(5):705-16. PubMed ID: 22842875
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transportin 1 colocalization with Fused in Sarcoma (FUS) inclusions is not characteristic for amyotrophic lateral sclerosis-FUS confirming disrupted nuclear import of mutant FUS and distinguishing it from frontotemporal lobar degeneration with FUS inclusions.
    Troakes C; Hortobágyi T; Vance C; Al-Sarraj S; Rogelj B; Shaw CE
    Neuropathol Appl Neurobiol; 2013 Aug; 39(5):553-61. PubMed ID: 22934812
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Knockdown of glutathione S-transferase leads to mislocalization and accumulation of cabeza, a
    Cha SJ; Yoon JH; Han YJ; Kim K
    J Neurogenet; 2023; 37(1-2):20-24. PubMed ID: 36437507
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NPM-hMLF1 fusion protein suppresses defects of a Drosophila FTLD model expressing the human FUS gene.
    Yamamoto I; Azuma Y; Kushimura Y; Yoshida H; Mizuta I; Mizuno T; Ueyama M; Nagai Y; Tokuda T; Yamaguchi M
    Sci Rep; 2018 Jul; 8(1):11291. PubMed ID: 30050143
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The RNA-binding protein FUS is chaperoned and imported into the nucleus by a network of import receptors.
    Baade I; Hutten S; Sternburg EL; Pörschke M; Hofweber M; Dormann D; Kehlenbach RH
    J Biol Chem; 2021; 296():100659. PubMed ID: 33857479
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.