BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

307 related articles for article (PubMed ID: 25448488)

  • 1. Dual targeting of the thioredoxin and glutathione antioxidant systems in malignant B cells: a novel synergistic therapeutic approach.
    Kiebala M; Skalska J; Casulo C; Brookes PS; Peterson DR; Hilchey SP; Dai Y; Grant S; Maggirwar SB; Bernstein SH
    Exp Hematol; 2015 Feb; 43(2):89-99. PubMed ID: 25448488
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting redox homeostasis in rhabdomyosarcoma cells: GSH-depleting agents enhance auranofin-induced cell death.
    Habermann KJ; Grünewald L; van Wijk S; Fulda S
    Cell Death Dis; 2017 Oct; 8(10):e3067. PubMed ID: 28981107
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Susceptibility of human head and neck cancer cells to combined inhibition of glutathione and thioredoxin metabolism.
    Sobhakumari A; Love-Homan L; Fletcher EV; Martin SM; Parsons AD; Spitz DR; Knudson CM; Simons AL
    PLoS One; 2012; 7(10):e48175. PubMed ID: 23118946
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Simultaneous inhibition of glutathione- and thioredoxin-dependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress.
    Scarbrough PM; Mapuskar KA; Mattson DM; Gius D; Watson WH; Spitz DR
    Free Radic Biol Med; 2012 Jan; 52(2):436-43. PubMed ID: 22100505
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting of the Glutathione, Thioredoxin, and Nrf2 Antioxidant Systems in Head and Neck Cancer.
    Roh JL; Jang H; Kim EH; Shin D
    Antioxid Redox Signal; 2017 Jul; 27(2):106-114. PubMed ID: 27733046
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhancement of Radiation Response in Breast Cancer Stem Cells by Inhibition of Thioredoxin- and Glutathione-Dependent Metabolism.
    Rodman SN; Spence JM; Ronnfeldt TJ; Zhu Y; Solst SR; O'Neill RA; Allen BG; Guan X; Spitz DR; Fath MA
    Radiat Res; 2016 Oct; 186(4):385-395. PubMed ID: 27643875
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of glutathione synthesis eliminates the adaptive response of ascitic hepatoma 22 cells to nedaplatin that targets thioredoxin reductase.
    Wang Y; Lu H; Wang D; Li S; Sun K; Wan X; Taylor EW; Zhang J
    Toxicol Appl Pharmacol; 2012 Dec; 265(3):342-50. PubMed ID: 22982619
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual pharmacological inhibition of glutathione and thioredoxin systems synergizes to kill colorectal carcinoma stem cells.
    Tanaka G; Inoue K; Shimizu T; Akimoto K; Kubota K
    Cancer Med; 2016 Sep; 5(9):2544-57. PubMed ID: 27485632
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cross-talk between two antioxidants, thioredoxin reductase and heme oxygenase-1, and therapeutic implications for multiple myeloma.
    Raninga PV; Di Trapani G; Vuckovic S; Tonissen KF
    Redox Biol; 2016 Aug; 8():175-85. PubMed ID: 26795735
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective targeting of the cysteine proteome by thioredoxin and glutathione redox systems.
    Go YM; Roede JR; Walker DI; Duong DM; Seyfried NT; Orr M; Liang Y; Pennell KD; Jones DP
    Mol Cell Proteomics; 2013 Nov; 12(11):3285-96. PubMed ID: 23946468
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Potentiation of arsenic trioxide cytotoxicity by Parthenolide and buthionine sulfoximine in murine and human leukemic cells.
    Duechler M; Stańczyk M; Czyz M; Stepnik M
    Cancer Chemother Pharmacol; 2008 Apr; 61(5):727-37. PubMed ID: 17594095
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Radioresistant Cervical Cancers Are Sensitive to Inhibition of Glycolysis and Redox Metabolism.
    Rashmi R; Huang X; Floberg JM; Elhammali AE; McCormick ML; Patti GJ; Spitz DR; Schwarz JK
    Cancer Res; 2018 Mar; 78(6):1392-1403. PubMed ID: 29339540
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glutathione and glutaredoxin act as a backup of human thioredoxin reductase 1 to reduce thioredoxin 1 preventing cell death by aurothioglucose.
    Du Y; Zhang H; Lu J; Holmgren A
    J Biol Chem; 2012 Nov; 287(45):38210-9. PubMed ID: 22977247
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Auranofin induces mesothelioma cell death through oxidative stress and GSH depletion.
    You BR; Park WH
    Oncol Rep; 2016 Jan; 35(1):546-51. PubMed ID: 26530353
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Potential Anticancer Activity of Auranofin.
    Onodera T; Momose I; Kawada M
    Chem Pharm Bull (Tokyo); 2019; 67(3):186-191. PubMed ID: 30827998
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species.
    Wang H; Bouzakoura S; de Mey S; Jiang H; Law K; Dufait I; Corbet C; Verovski V; Gevaert T; Feron O; Van den Berge D; Storme G; De Ridder M
    Oncotarget; 2017 May; 8(22):35728-35742. PubMed ID: 28415723
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ifosfamide induces acute renal failure via inhibition of the thioredoxin reductase activity.
    Zhang J; Lu H
    Free Radic Biol Med; 2007 Dec; 43(12):1574-83. PubMed ID: 18037123
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin.
    Lu Y; Cederbaum A
    Free Radic Biol Med; 2007 Oct; 43(7):1061-75. PubMed ID: 17761302
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The thioredoxin antioxidant system.
    Lu J; Holmgren A
    Free Radic Biol Med; 2014 Jan; 66():75-87. PubMed ID: 23899494
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thioredoxin-1 redox signaling regulates cell survival in response to hyperoxia.
    Floen MJ; Forred BJ; Bloom EJ; Vitiello PF
    Free Radic Biol Med; 2014 Oct; 75():167-77. PubMed ID: 25106706
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.