596 related articles for article (PubMed ID: 25450489)
1. Pathogenesis associated with a restrictive cardiomyopathy mutant in cardiac troponin T is due to reduced protein stability and greatly increased myofilament Ca2+ sensitivity.
Parvatiyar MS; Pinto JR
Biochim Biophys Acta; 2015 Feb; 1850(2):365-72. PubMed ID: 25450489
[TBL] [Abstract][Full Text] [Related]
2. Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization.
Lu QW; Morimoto S; Harada K; Du CK; Takahashi-Yanaga F; Miwa Y; Sasaguri T; Ohtsuki I
J Mol Cell Cardiol; 2003 Dec; 35(12):1421-7. PubMed ID: 14654368
[TBL] [Abstract][Full Text] [Related]
3. A troponin T mutation that causes infantile restrictive cardiomyopathy increases Ca2+ sensitivity of force development and impairs the inhibitory properties of troponin.
Pinto JR; Parvatiyar MS; Jones MA; Liang J; Potter JD
J Biol Chem; 2008 Jan; 283(4):2156-66. PubMed ID: 18032382
[TBL] [Abstract][Full Text] [Related]
4. Effects of protein kinase A phosphorylation on signaling between cardiac troponin I and the N-terminal domain of cardiac troponin C.
Chandra M; Dong WJ; Pan BS; Cheung HC; Solaro RJ
Biochemistry; 1997 Oct; 36(43):13305-11. PubMed ID: 9341222
[TBL] [Abstract][Full Text] [Related]
5. Interactions at the NH2-terminal interface of cardiac troponin I modulate myofilament activation.
Rarick HM; Tang HP; Guo XD; Martin AF; Solaro RJ
J Mol Cell Cardiol; 1999 Feb; 31(2):363-75. PubMed ID: 10093049
[TBL] [Abstract][Full Text] [Related]
6. Effects of PKA phosphorylation of cardiac troponin I and strong crossbridge on conformational transitions of the N-domain of cardiac troponin C in regulated thin filaments.
Dong WJ; Jayasundar JJ; An J; Xing J; Cheung HC
Biochemistry; 2007 Aug; 46(34):9752-61. PubMed ID: 17676764
[TBL] [Abstract][Full Text] [Related]
7. Generation and functional characterization of knock-in mice harboring the cardiac troponin I-R21C mutation associated with hypertrophic cardiomyopathy.
Wang Y; Pinto JR; Solis RS; Dweck D; Liang J; Diaz-Perez Z; Ge Y; Walker JW; Potter JD
J Biol Chem; 2012 Jan; 287(3):2156-67. PubMed ID: 22086914
[TBL] [Abstract][Full Text] [Related]
8. Cardiac troponin T mutations: correlation between the type of mutation and the nature of myofilament dysfunction in transgenic mice.
Montgomery DE; Tardiff JC; Chandra M
J Physiol; 2001 Oct; 536(Pt 2):583-92. PubMed ID: 11600691
[TBL] [Abstract][Full Text] [Related]
9. Restrictive Cardiomyopathy Troponin I R145W Mutation Does Not Perturb Myofilament Length-dependent Activation in Human Cardiac Sarcomeres.
Dvornikov AV; Smolin N; Zhang M; Martin JL; Robia SL; de Tombe PP
J Biol Chem; 2016 Oct; 291(41):21817-21828. PubMed ID: 27557662
[TBL] [Abstract][Full Text] [Related]
10. Familial dilated cardiomyopathy mutations uncouple troponin I phosphorylation from changes in myofibrillar Ca²⁺ sensitivity.
Memo M; Leung MC; Ward DG; dos Remedios C; Morimoto S; Zhang L; Ravenscroft G; McNamara E; Nowak KJ; Marston SB; Messer AE
Cardiovasc Res; 2013 Jul; 99(1):65-73. PubMed ID: 23539503
[TBL] [Abstract][Full Text] [Related]
11. The troponin C G159D mutation blunts myofilament desensitization induced by troponin I Ser23/24 phosphorylation.
Biesiadecki BJ; Kobayashi T; Walker JS; Solaro RJ; de Tombe PP
Circ Res; 2007 May; 100(10):1486-93. PubMed ID: 17446435
[TBL] [Abstract][Full Text] [Related]
12. The N-terminal region of troponin T is essential for the maximal activation of rat cardiac myofilaments.
Chandra M; Montgomery DE; Kim JJ; Solaro RJ
J Mol Cell Cardiol; 1999 Apr; 31(4):867-80. PubMed ID: 10329214
[TBL] [Abstract][Full Text] [Related]
13. Fetal cardiac troponin isoforms rescue the increased Ca2+ sensitivity produced by a novel double deletion in cardiac troponin T linked to restrictive cardiomyopathy: a clinical, genetic, and functional approach.
Pinto JR; Yang SW; Hitz MP; Parvatiyar MS; Jones MA; Liang J; Kokta V; Talajic M; Tremblay N; Jaeggi M; Andelfinger G; Potter JD
J Biol Chem; 2011 Jun; 286(23):20901-12. PubMed ID: 21502316
[TBL] [Abstract][Full Text] [Related]
14. Effects of protein kinase C dependent phosphorylation and a familial hypertrophic cardiomyopathy-related mutation of cardiac troponin I on structural transition of troponin C and myofilament activation.
Kobayashi T; Dong WJ; Burkart EM; Cheung HC; Solaro RJ
Biochemistry; 2004 May; 43(20):5996-6004. PubMed ID: 15147183
[TBL] [Abstract][Full Text] [Related]
15. Structural kinetics of cardiac troponin C mutants linked to familial hypertrophic and dilated cardiomyopathy in troponin complexes.
Dong WJ; Xing J; Ouyang Y; An J; Cheung HC
J Biol Chem; 2008 Feb; 283(6):3424-3432. PubMed ID: 18063575
[TBL] [Abstract][Full Text] [Related]
16. Protein kinase A-dependent modulation of Ca2+ sensitivity in cardiac and fast skeletal muscles after reconstitution with cardiac troponin.
Matsuba D; Terui T; O-Uchi J; Tanaka H; Ojima T; Ohtsuki I; Ishiwata S; Kurihara S; Fukuda N
J Gen Physiol; 2009 Jun; 133(6):571-81. PubMed ID: 19433622
[TBL] [Abstract][Full Text] [Related]
17. Effects of Cardiac Troponin I Mutation P83S on Contractile Properties and the Modulation by PKA-Mediated Phosphorylation.
Cheng Y; Lindert S; Oxenford L; Tu AY; McCulloch AD; Regnier M
J Phys Chem B; 2016 Aug; 120(33):8238-53. PubMed ID: 27150586
[TBL] [Abstract][Full Text] [Related]
18. Challenging current paradigms related to cardiomyopathies. Are changes in the Ca2+ sensitivity of myofilaments containing cardiac troponin C mutations (G159D and L29Q) good predictors of the phenotypic outcomes?
Dweck D; Hus N; Potter JD
J Biol Chem; 2008 Nov; 283(48):33119-28. PubMed ID: 18820258
[TBL] [Abstract][Full Text] [Related]
19. The influence of trout cardiac troponin I and PKA phosphorylation on the Ca2+ affinity of the cardiac troponin complex.
Kirkpatrick KP; Robertson AS; Klaiman JM; Gillis TE
J Exp Biol; 2011 Jun; 214(Pt 12):1981-8. PubMed ID: 21613513
[TBL] [Abstract][Full Text] [Related]
20. Dilated Cardiomyopathy Mutations and Phosphorylation disrupt the Active Orientation of Cardiac Troponin C.
Mahmud Z; Dhami PS; Rans C; Liu PB; Hwang PM
J Mol Biol; 2021 Jun; 433(13):167010. PubMed ID: 33901537
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
