90 related articles for article (PubMed ID: 25451572)
1. The role of the efflux carriers Abcg2 and Abcc2 for the hepatobiliary elimination of benzo[a]pyrene and its metabolites in mice.
Kranz J; Hessel S; Aretz J; Seidel A; Petzinger E; Geyer J; Lampen A
Chem Biol Interact; 2014 Dec; 224():36-41. PubMed ID: 25451572
[TBL] [Abstract][Full Text] [Related]
2. Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice.
Nezasa K; Tian X; Zamek-Gliszczynski MJ; Patel NJ; Raub TJ; Brouwer KL
Drug Metab Dispos; 2006 Apr; 34(4):718-23. PubMed ID: 16434545
[TBL] [Abstract][Full Text] [Related]
3. Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo.
Vlaming ML; Pala Z; van Esch A; Wagenaar E; de Waart DR; van de Wetering K; van der Kruijssen CM; Oude Elferink RP; van Tellingen O; Schinkel AH
Clin Cancer Res; 2009 May; 15(9):3084-93. PubMed ID: 19383815
[TBL] [Abstract][Full Text] [Related]
4. Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2.
de Waart DR; Vlaming ML; Kunne C; Schinkel AH; Oude Elferink RP
Drug Metab Dispos; 2009 Aug; 37(8):1698-702. PubMed ID: 19443695
[TBL] [Abstract][Full Text] [Related]
5. Impact of abcc2 [multidrug resistance-associated protein (MRP) 2], abcc3 (MRP3), and abcg2 (breast cancer resistance protein) on the oral pharmacokinetics of methotrexate and its main metabolite 7-hydroxymethotrexate.
Vlaming ML; van Esch A; van de Steeg E; Pala Z; Wagenaar E; van Tellingen O; Schinkel AH
Drug Metab Dispos; 2011 Aug; 39(8):1338-44. PubMed ID: 21566011
[TBL] [Abstract][Full Text] [Related]
6. Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo.
Vlaming ML; van Esch A; Pala Z; Wagenaar E; van de Wetering K; van Tellingen O; Schinkel AH
Mol Cancer Ther; 2009 Dec; 8(12):3350-9. PubMed ID: 19996279
[TBL] [Abstract][Full Text] [Related]
7. Hepatic transport mechanisms of cholyl-L-lysyl-fluorescein.
de Waart DR; Häusler S; Vlaming ML; Kunne C; Hänggi E; Gruss HJ; Oude Elferink RP; Stieger B
J Pharmacol Exp Ther; 2010 Jul; 334(1):78-86. PubMed ID: 20388726
[TBL] [Abstract][Full Text] [Related]
8. Influence of efflux transporters on liver, bile and brain disposition of amitriptyline in mice.
Abaut AY; Chevanne F; Le Corre P
Int J Pharm; 2009 Aug; 378(1-2):80-5. PubMed ID: 19508886
[TBL] [Abstract][Full Text] [Related]
9. Overlapping functions of ABC transporters in topotecan disposition as determined in gene knockout mouse models.
Tiwari AK; Zhang R; Gallo JM
Mol Cancer Ther; 2013 Jul; 12(7):1343-55. PubMed ID: 23635651
[TBL] [Abstract][Full Text] [Related]
10. The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin.
Merino G; Jonker JW; Wagenaar E; van Herwaarden AE; Schinkel AH
Mol Pharmacol; 2005 May; 67(5):1758-64. PubMed ID: 15709111
[TBL] [Abstract][Full Text] [Related]
11. Hepatic clearance of reactive glucuronide metabolites of diclofenac in the mouse is dependent on multiple ATP-binding cassette efflux transporters.
Lagas JS; Sparidans RW; Wagenaar E; Beijnen JH; Schinkel AH
Mol Pharmacol; 2010 Apr; 77(4):687-94. PubMed ID: 20086033
[TBL] [Abstract][Full Text] [Related]
12. Multidrug resistance-associated proteins are involved in the transport of the glutathione conjugates of the ultimate carcinogen of benzo[a]pyrene in human Caco-2 cells.
Hessel S; John A; Seidel A; Lampen A
Arch Toxicol; 2013 Feb; 87(2):269-80. PubMed ID: 22899102
[TBL] [Abstract][Full Text] [Related]
13. Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.
Vlaming ML; Pala Z; van Esch A; Wagenaar E; van Tellingen O; de Waart DR; Oude Elferink RP; van de Wetering K; Schinkel AH
Clin Cancer Res; 2008 Dec; 14(24):8152-60. PubMed ID: 19088030
[TBL] [Abstract][Full Text] [Related]
14. Improved extrapolation of hepatobiliary clearance from in vitro sandwich cultured rat hepatocytes through absolute quantification of hepatobiliary transporters.
Li N; Singh P; Mandrell KM; Lai Y
Mol Pharm; 2010 Jun; 7(3):630-41. PubMed ID: 20438085
[TBL] [Abstract][Full Text] [Related]
15. Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers.
Tian X; Swift B; Zamek-Gliszczynski MJ; Belinsky MG; Kruh GD; Brouwer KL
Drug Metab Dispos; 2008 May; 36(5):911-5. PubMed ID: 18276836
[TBL] [Abstract][Full Text] [Related]
16. Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models.
Wang Z; Zhou Q; Kruh GD; Gallo JM
Drug Metab Dispos; 2011 Nov; 39(11):2155-61. PubMed ID: 21841039
[TBL] [Abstract][Full Text] [Related]
17. Hepatocyte-Specific Deletion of EGFR in Mice Reduces Hepatic Abcg2 Transport Activity Measured by [
Traxl A; Komposch K; Glitzner E; Wanek T; Mairinger S; Langer O; Sibilia M
Drug Metab Dispos; 2017 Oct; 45(10):1093-1100. PubMed ID: 28790147
[TBL] [Abstract][Full Text] [Related]
18. P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 determine the pharmacokinetics of etoposide.
Lagas JS; Fan L; Wagenaar E; Vlaming ML; van Tellingen O; Beijnen JH; Schinkel AH
Clin Cancer Res; 2010 Jan; 16(1):130-40. PubMed ID: 20028753
[TBL] [Abstract][Full Text] [Related]
19. Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice.
Vlaming ML; Mohrmann K; Wagenaar E; de Waart DR; Elferink RP; Lagas JS; van Tellingen O; Vainchtein LD; Rosing H; Beijnen JH; Schellens JH; Schinkel AH
J Pharmacol Exp Ther; 2006 Jul; 318(1):319-27. PubMed ID: 16611851
[TBL] [Abstract][Full Text] [Related]
20. Metabolism of benzo[a]pyrene in the perfused rat liver: factors affecting the release of phenolic metabolites into the bile and perfusate.
Sweeny DJ; Reinke LA
Carcinogenesis; 1987 Jun; 8(6):779-83. PubMed ID: 3608074
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]