BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

392 related articles for article (PubMed ID: 25453103)

  • 1. hERG 1b is critical for human cardiac repolarization.
    Jones DK; Liu F; Vaidyanathan R; Eckhardt LL; Trudeau MC; Robertson GA
    Proc Natl Acad Sci U S A; 2014 Dec; 111(50):18073-7. PubMed ID: 25453103
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dominant negative consequences of a hERG 1b-specific mutation associated with intrauterine fetal death.
    Jones DK; Liu F; Dombrowski N; Joshi S; Robertson GA
    Prog Biophys Mol Biol; 2016 Jan; 120(1-3):67-76. PubMed ID: 26772437
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tbx20 controls the expression of the KCNH2 gene and of hERG channels.
    Caballero R; Utrilla RG; Amorós I; Matamoros M; Pérez-Hernández M; Tinaquero D; Alfayate S; Nieto-Marín P; Guerrero-Serna G; Liu QH; Ramos-Mondragón R; Ponce-Balbuena D; Herron T; Campbell KF; Filgueiras-Rama D; Peinado R; López-Sendón JL; Jalife J; Delpón E; Tamargo J
    Proc Natl Acad Sci U S A; 2017 Jan; 114(3):E416-E425. PubMed ID: 28049825
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Physiological properties of hERG 1a/1b heteromeric currents and a hERG 1b-specific mutation associated with Long-QT syndrome.
    Sale H; Wang J; O'Hara TJ; Tester DJ; Phartiyal P; He JQ; Rudy Y; Ackerman MJ; Robertson GA
    Circ Res; 2008 Sep; 103(7):e81-95. PubMed ID: 18776039
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes.
    Guo J; Massaeli H; Li W; Xu J; Luo T; Shaw J; Kirshenbaum LA; Zhang S
    J Pharmacol Exp Ther; 2007 Jun; 321(3):911-20. PubMed ID: 17377062
    [TBL] [Abstract][Full Text] [Related]  

  • 6. C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon.
    Choe CU; Schulze-Bahr E; Neu A; Xu J; Zhu ZI; Sauter K; Bähring R; Priori S; Guicheney P; Mönnig G; Neapolitano C; Heidemann J; Clancy CE; Pongs O; Isbrandt D
    Hum Mol Genet; 2006 Oct; 15(19):2888-902. PubMed ID: 16923798
    [TBL] [Abstract][Full Text] [Related]  

  • 7. hERG 1a LQT2 C-terminus truncation mutants display hERG 1b-dependent dominant negative mechanisms.
    Puckerin A; Aromolaran KA; Chang DD; Zukin RS; Colecraft HM; Boutjdir M; Aromolaran AS
    Heart Rhythm; 2016 May; 13(5):1121-1130. PubMed ID: 26775140
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
    Liu QN; Trudeau MC
    PLoS One; 2015; 10(4):e0123951. PubMed ID: 25923442
    [TBL] [Abstract][Full Text] [Related]  

  • 9. HIV Tat protein inhibits hERG K+ channels: a potential mechanism of HIV infection induced LQTs.
    Bai YL; Liu HB; Sun B; Zhang Y; Li Q; Hu CW; Zhu JX; Gong DM; Teng X; Zhang Q; Yang BF; Dong DL
    J Mol Cell Cardiol; 2011 Nov; 51(5):876-80. PubMed ID: 21820442
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Re-trafficking of hERG reverses long QT syndrome 2 phenotype in human iPS-derived cardiomyocytes.
    Mehta A; Sequiera GL; Ramachandra CJ; Sudibyo Y; Chung Y; Sheng J; Wong KY; Tan TH; Wong P; Liew R; Shim W
    Cardiovasc Res; 2014 Jun; 102(3):497-506. PubMed ID: 24623279
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cotranslational association of mRNA encoding subunits of heteromeric ion channels.
    Liu F; Jones DK; de Lange WJ; Robertson GA
    Proc Natl Acad Sci U S A; 2016 Apr; 113(17):4859-64. PubMed ID: 27078096
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Time course and voltage dependence of expressed HERG current compared with native "rapid" delayed rectifier K current during the cardiac ventricular action potential.
    Hancox JC; Levi AJ; Witchel HJ
    Pflugers Arch; 1998 Nov; 436(6):843-53. PubMed ID: 9799397
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Clemastine, a conventional antihistamine, is a high potency inhibitor of the HERG K+ channel.
    Ridley JM; Milnes JT; Hancox JC; Witchel HJ
    J Mol Cell Cardiol; 2006 Jan; 40(1):107-18. PubMed ID: 16288909
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of the human ether-a-go-go-related gene (hERG) potassium channel by Nedd4 family interacting proteins (Ndfips).
    Kang Y; Guo J; Yang T; Li W; Zhang S
    Biochem J; 2015 Nov; 472(1):71-82. PubMed ID: 26363003
    [TBL] [Abstract][Full Text] [Related]  

  • 15. hERG1 channel subunit composition mediates proton inhibition of rapid delayed rectifier potassium current (I
    Ukachukwu CU; Jimenez-Vazquez EN; Jain A; Jones DK
    J Biol Chem; 2023 Feb; 299(2):102778. PubMed ID: 36496073
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mouse ERG K(+) channel clones reveal differences in protein trafficking and function.
    Lin EC; Moungey BM; Lim E; Concannon SP; Anderson CL; Kyle JW; Makielski JC; Balijepalli SY; January CT
    J Am Heart Assoc; 2014 Dec; 3(6):e001491. PubMed ID: 25497881
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HERG channel (dys)function revealed by dynamic action potential clamp technique.
    Berecki G; Zegers JG; Verkerk AO; Bhuiyan ZA; de Jonge B; Veldkamp MW; Wilders R; van Ginneken AC
    Biophys J; 2005 Jan; 88(1):566-78. PubMed ID: 15475579
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
    Davie C; Pierre-Valentin J; Pollard C; Standen N; Mitcheson J; Alexander P; Thong B
    J Cardiovasc Electrophysiol; 2004 Nov; 15(11):1302-9. PubMed ID: 15574182
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intracellular Mechanism of Rosuvastatin-Induced Decrease in Mature hERG Protein Expression on Membrane.
    Feng PF; Zhang B; Zhao L; Fang Q; Liu Y; Wang JN; Xu XQ; Xue H; Li Y; Yan CC; Zhao X; Li BX
    Mol Pharm; 2019 Apr; 16(4):1477-1488. PubMed ID: 30807184
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Computational Models for Understanding of Structure, Function and Pharmacology of the Cardiac Potassium Channel Kv11.1 (hERG).
    Wacker S; Noskov SY; Perissinotti LL
    Curr Top Med Chem; 2017; 17(23):2681-2702. PubMed ID: 28413954
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.