95 related articles for article (PubMed ID: 25453800)
41. MF63 [2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a selective microsomal prostaglandin E synthase-1 inhibitor, relieves pyresis and pain in preclinical models of inflammation.
Xu D; Rowland SE; Clark P; Giroux A; Côté B; Guiral S; Salem M; Ducharme Y; Friesen RW; Méthot N; Mancini J; Audoly L; Riendeau D
J Pharmacol Exp Ther; 2008 Sep; 326(3):754-63. PubMed ID: 18524979
[TBL] [Abstract][Full Text] [Related]
42. Effect of etidronate on COX-2 expression and PGE(2) production in macrophage-like RAW 264.7 cells stimulated by titanium particles.
Suzuki Y; Nishiyama T; Hasuda K; Fujishiro T; Niikura T; Hayashi S; Hashimoto S; Kurosaka M
J Orthop Sci; 2007 Nov; 12(6):568-77. PubMed ID: 18040640
[TBL] [Abstract][Full Text] [Related]
43. Involvement of the constitutive prostaglandin E synthase cPGES/p23 in expression of an initial prostaglandin E2 inactivating enzyme, 15-PGDH.
Nakatani Y; Hokonohara Y; Tajima Y; Kudo I; Hara S
Prostaglandins Other Lipid Mediat; 2011 Apr; 94(3-4):112-7. PubMed ID: 21334450
[TBL] [Abstract][Full Text] [Related]
44. Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer.
Rådmark O; Samuelsson B
J Intern Med; 2010 Jul; 268(1):5-14. PubMed ID: 20497297
[TBL] [Abstract][Full Text] [Related]
45. Inhibitory effects of kaurenoic acid from Aralia continentalis on LPS-induced inflammatory response in RAW264.7 macrophages.
Choi RJ; Shin EM; Jung HA; Choi JS; Kim YS
Phytomedicine; 2011 Jun; 18(8-9):677-82. PubMed ID: 21211951
[TBL] [Abstract][Full Text] [Related]
46. Effects of compounds from bi-qi capsule on the expression of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 macrophages.
Wang QS; Cui YL; Wang YF; Chi W
J Ethnopharmacol; 2011 Jul; 136(3):480-7. PubMed ID: 20558268
[TBL] [Abstract][Full Text] [Related]
47. Selective inducible microsomal prostaglandin E(2) synthase-1 (mPGES-1) inhibitors derived from an oxicam template.
Wang J; Limburg D; Carter J; Mbalaviele G; Gierse J; Vazquez M
Bioorg Med Chem Lett; 2010 Mar; 20(5):1604-9. PubMed ID: 20144869
[TBL] [Abstract][Full Text] [Related]
48. Structure-activity relationship of nonacidic quinazolinone inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1).
Rörsch F; Buscató E; Deckmann K; Schneider G; Schubert-Zsilavecz M; Geisslinger G; Proschak E; Grösch S
J Med Chem; 2012 Apr; 55(8):3792-803. PubMed ID: 22449023
[TBL] [Abstract][Full Text] [Related]
49. Aspirin inhibits MMP-9 mRNA expression and release via the PPARalpha/gamma and COX-2/mPGES-1-mediated pathways in macrophages derived from THP-1 cells.
Xue J; Hua YN; Xie ML; Gu ZL
Biomed Pharmacother; 2010 Feb; 64(2):118-23. PubMed ID: 19880272
[TBL] [Abstract][Full Text] [Related]
50. Despite transcriptional and functional coordination, cyclooxygenase-2 and microsomal prostaglandin E synthase-1 largely reside in distinct lipid microdomains in WISH epithelial cells.
Ackerman WE; Robinson JM; Kniss DA
J Histochem Cytochem; 2005 Nov; 53(11):1391-401. PubMed ID: 15983118
[TBL] [Abstract][Full Text] [Related]
51. Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6-diphenyl-1,2,4-triazin-3(2H)-one derivatives bearing 5-substituted 1,3,4-oxadiazole as potential anti-inflammatory and analgesic agents.
Banerjee AG; Das N; Shengule SA; Srivastava RS; Shrivastava SK
Eur J Med Chem; 2015 Aug; 101():81-95. PubMed ID: 26117820
[TBL] [Abstract][Full Text] [Related]
52. Synthesis and in vitro evaluation of 1,2,4-triazolo[1,5-a][1,3,5]triazine derivatives as thymidine phosphorylase inhibitors.
Bera H; Dolzhenko AV; Sun L; Dutta Gupta S; Chui WK
Chem Biol Drug Des; 2013 Sep; 82(3):351-60. PubMed ID: 23758794
[TBL] [Abstract][Full Text] [Related]
53. Synthesis and SAR study of imidazoquinolines as a novel structural class of microsomal prostaglandin E₂ synthase-1 inhibitors.
Shiro T; Takahashi H; Kakiguchi K; Inoue Y; Masuda K; Nagata H; Tobe M
Bioorg Med Chem Lett; 2012 Jan; 22(1):285-8. PubMed ID: 22137787
[TBL] [Abstract][Full Text] [Related]
54. Styrylquinazolines: a new class of inhibitors on prostaglandin E2 production in lipopolysaccharide-activated macrophage cells.
Park JH; Min HY; Kim SS; Lee JY; Lee SK; Lee YS
Arch Pharm (Weinheim); 2004 Jan; 337(1):20-4. PubMed ID: 14760624
[TBL] [Abstract][Full Text] [Related]
55. Prostaglandin E(2) synthase inhibition as a therapeutic target.
Iyer JP; Srivastava PK; Dev R; Dastidar SG; Ray A
Expert Opin Ther Targets; 2009 Jul; 13(7):849-65. PubMed ID: 19530988
[TBL] [Abstract][Full Text] [Related]
56. Retinoic acid enhances prostaglandin E2 production through increased expression of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 in rat brain microglia.
Kim B; Lee JH; Yang MS; Jou I; Joe EH
J Neurosci Res; 2008 May; 86(6):1353-60. PubMed ID: 18183617
[TBL] [Abstract][Full Text] [Related]
57. Inhibition of prostaglandin production by a structurally-optimized flavonoid derivative, 2',4',7-trimethoxyflavone and cellular action mechanism.
Han CK; Son MJ; Chang HW; Chi YS; Park H; Kim HP
Biol Pharm Bull; 2005 Aug; 28(8):1366-70. PubMed ID: 16079475
[TBL] [Abstract][Full Text] [Related]
58. Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1.
Gosset M; Pigenet A; Salvat C; Berenbaum F; Jacques C
J Immunol; 2010 Nov; 185(10):6244-52. PubMed ID: 20943996
[TBL] [Abstract][Full Text] [Related]
59. Alkyl derivatives of 1,3,5-triazine as histamine H
Łażewska D; Mogilski S; Hagenow S; Kuder K; Głuch-Lutwin M; Siwek A; Więcek M; Kaleta M; Seibel U; Buschauer A; Filipek B; Stark H; Kieć-Kononowicz K
Bioorg Med Chem; 2019 Apr; 27(7):1254-1262. PubMed ID: 30792106
[TBL] [Abstract][Full Text] [Related]
60. Synthesis and biological activity of aminophthalazines and aminopyridazines as novel inhibitors of PGE2 production in cells.
Medda F; Sells E; Chang HH; Dietrich J; Chappeta S; Smith B; Gokhale V; Meuillet EJ; Hulme C
Bioorg Med Chem Lett; 2013 Jan; 23(2):528-31. PubMed ID: 23237838
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]