These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 25454499)

  • 1. Design and nuclear magnetic resonance (NMR) structure determination of the second extracellular immunoglobulin tyrosine kinase A (TrkAIg2) domain construct for binding site elucidation in drug discovery.
    Shoemark DK; Williams C; Fahey MS; Watson JJ; Tyler SJ; Scoltock SJ; Ellis RZ; Wickenden E; Burton AJ; Hemmings JL; Bailey CD; Dawbarn D; Jane DE; Willis CL; Sessions RB; Allen SJ; Crump MP
    J Med Chem; 2015 Jan; 58(2):767-77. PubMed ID: 25454499
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis of the transmembrane domain dimerization and rotation in the activation mechanism of the TRKA receptor by nerve growth factor.
    Franco ML; Nadezhdin KD; Goncharuk SA; Mineev KS; Arseniev AS; Vilar M
    J Biol Chem; 2020 Jan; 295(1):275-286. PubMed ID: 31801826
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of critical residues within the conserved and specificity patches of nerve growth factor leading to survival or differentiation.
    Mahapatra S; Mehta H; Woo SB; Neet KE
    J Biol Chem; 2009 Nov; 284(48):33600-13. PubMed ID: 19762468
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification and structure of the nerve growth factor binding site on TrkA.
    Robertson AG; Banfield MJ; Allen SJ; Dando JA; Mason GG; Tyler SJ; Bennett GS; Brain SD; Clarke AR; Naylor RL; Wilcock GK; Brady RL; Dawbarn D
    Biochem Biophys Res Commun; 2001 Mar; 282(1):131-41. PubMed ID: 11263982
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Congenital insensitivity to pain with anhidrosis (CIPA): effect of TRKA (NTRK1) missense mutations on autophosphorylation of the receptor tyrosine kinase for nerve growth factor.
    Mardy S; Miura Y; Endo F; Matsuda I; Indo Y
    Hum Mol Genet; 2001 Feb; 10(3):179-88. PubMed ID: 11159935
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparison of nerve growth factor receptor binding models using heterodimeric muteins.
    Mehta HM; Woo SB; Neet KE
    J Neurosci Res; 2012 Dec; 90(12):2259-71. PubMed ID: 22903500
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors.
    Wehrman T; He X; Raab B; Dukipatti A; Blau H; Garcia KC
    Neuron; 2007 Jan; 53(1):25-38. PubMed ID: 17196528
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nerve growth factor: structure and function.
    Wiesmann C; de Vos AM
    Cell Mol Life Sci; 2001 May; 58(5-6):748-59. PubMed ID: 11437236
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TrkA immunoglobulin-like ligand binding domains inhibit spontaneous activation of the receptor.
    Arevalo JC; Conde B; Hempstead BL; Chao MV; Martin-Zanca D; Perez P
    Mol Cell Biol; 2000 Aug; 20(16):5908-16. PubMed ID: 10913174
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A double cysteine trkA mutant exhibiting reduced NGF binding and delayed Erk signaling.
    Jiang H; Movsesyan V; Liu XW; Katagiri Y; Monshipoyri M; Lazarovici P
    J Mol Neurosci; 2001 Dec; 17(3):293-302. PubMed ID: 11859925
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel mutation within the extracellular domain of TrkA causes constitutive receptor activation.
    Arevalo JC; Conde B; Hempstead BI; Chao MV; Martín-Zanca D; Pérez P
    Oncogene; 2001 Mar; 20(10):1229-34. PubMed ID: 11313867
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and solution structure of functional peptide mimetics of nerve growth factor.
    Beglova N; Maliartchouk S; Ekiel I; Zaccaro MC; Saragovi HU; Gehring K
    J Med Chem; 2000 Sep; 43(19):3530-40. PubMed ID: 11000007
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor.
    Wiesmann C; Ultsch MH; Bass SH; de Vos AM
    Nature; 1999 Sep; 401(6749):184-8. PubMed ID: 10490030
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neutralization of NGF-TrkA receptor interaction by the novel antagonistic anti-TrkA monoclonal antibody MNAC13: a structural insight.
    Covaceuszach S; Cattaneo A; Lamba D
    Proteins; 2005 Feb; 58(3):717-27. PubMed ID: 15625712
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TrkA receptor "hot spots" for binding of NT-3 as a heterologous ligand.
    Ivanisevic L; Zheng W; Woo SB; Neet KE; Saragovi HU
    J Biol Chem; 2007 Jun; 282(23):16754-63. PubMed ID: 17439940
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel inducible tyrosine kinase receptor to regulate signal transduction and neurite outgrowth.
    Alfa RW; Tuszynski MH; Blesch A
    J Neurosci Res; 2009 Sep; 87(12):2624-31. PubMed ID: 19405107
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NGF stimulation of erk phosphorylation is impaired by a point mutation in the transmembrane domain of trkA receptor.
    Monshipouri M; Jiang H; Lazarovici P
    J Mol Neurosci; 2000; 14(1-2):69-76. PubMed ID: 10854038
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure and functional implication of the RUN domain of human NESCA.
    Sun Q; Han C; Liu L; Wang Y; Deng H; Bai L; Jiang T
    Protein Cell; 2012 Aug; 3(8):609-17. PubMed ID: 22821014
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Low molecular weight, non-peptidic agonists of TrkA receptor with NGF-mimetic activity.
    Scarpi D; Cirelli D; Matrone C; Castronovo G; Rosini P; Occhiato EG; Romano F; Bartali L; Clemente AM; Bottegoni G; Cavalli A; De Chiara G; Bonini P; Calissano P; Palamara AT; Garaci E; Torcia MG; Guarna A; Cozzolino F
    Cell Death Dis; 2012 Sep; 3(9):e389. PubMed ID: 22951986
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody.
    Covaceuszach S; Cassetta A; Konarev PV; Gonfloni S; Rudolph R; Svergun DI; Lamba D; Cattaneo A
    J Mol Biol; 2008 Sep; 381(4):881-96. PubMed ID: 18635195
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.