BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 25454514)

  • 1. Profilin-1 overexpression in MDA-MB-231 breast cancer cells is associated with alterations in proteomics biomarkers of cell proliferation, survival, and motility as revealed by global proteomics analyses.
    Coumans JV; Gau D; Poljak A; Wasinger V; Roy P; Moens PD
    OMICS; 2014 Dec; 18(12):778-91. PubMed ID: 25454514
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Profilin-1 overexpression inhibits proliferation of MDA-MB-231 breast cancer cells partly through p27kip1 upregulation.
    Zou L; Ding Z; Roy P
    J Cell Physiol; 2010 Jun; 223(3):623-9. PubMed ID: 20143334
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Profilin-1 overexpression upregulates PTEN and suppresses AKT activation in breast cancer cells.
    Das T; Bae YH; Wells A; Roy P
    J Cell Physiol; 2009 Feb; 218(2):436-43. PubMed ID: 18937284
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Profilin-1 is a negative regulator of mammary carcinoma aggressiveness.
    Zou L; Jaramillo M; Whaley D; Wells A; Panchapakesa V; Das T; Roy P
    Br J Cancer; 2007 Nov; 97(10):1361-71. PubMed ID: 17940506
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Profilin 1 obtained by proteomic analysis in all-trans retinoic acid-treated hepatocarcinoma cell lines is involved in inhibition of cell proliferation and migration.
    Wu N; Zhang W; Yang Y; Liang YL; Wang LY; Jin JW; Cai XM; Zha XL
    Proteomics; 2006 Nov; 6(22):6095-106. PubMed ID: 17051635
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of profilin-1 expression enhances breast cancer cell motility by Ena/VASP proteins.
    Bae YH; Ding Z; Zou L; Wells A; Gertler F; Roy P
    J Cell Physiol; 2009 May; 219(2):354-64. PubMed ID: 19115233
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Silencing profilin-1 inhibits gastric cancer progression via integrin β1/focal adhesion kinase pathway modulation.
    Cheng YJ; Zhu ZX; Zhou JS; Hu ZQ; Zhang JP; Cai QP; Wang LH
    World J Gastroenterol; 2015 Feb; 21(8):2323-35. PubMed ID: 25741138
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A balanced level of profilin-1 promotes stemness and tumor-initiating potential of breast cancer cells.
    Jiang C; Ding Z; Joy M; Chakraborty S; Kim SH; Bottcher R; Condeelis J; Singh S; Roy P
    Cell Cycle; 2017; 16(24):2366-2373. PubMed ID: 28699810
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BRCA1 deficiency in ovarian cancer is associated with alteration in expression of several key regulators of cell motility - A proteomics study.
    Gau DM; Lesnock JL; Hood BL; Bhargava R; Sun M; Darcy K; Luthra S; Chandran U; Conrads TP; Edwards RP; Kelley JL; Krivak TC; Roy P
    Cell Cycle; 2015; 14(12):1884-92. PubMed ID: 25927284
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Profilin-1 overexpression restores adherens junctions in MDA-MB-231 breast cancer cells in R-cadherin-dependent manner.
    Zou L; Hazan R; Roy P
    Cell Motil Cytoskeleton; 2009 Dec; 66(12):1048-56. PubMed ID: 19593789
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Profilin-1 suppresses tumorigenicity in pancreatic cancer through regulation of the SIRT3-HIF1α axis.
    Yao W; Ji S; Qin Y; Yang J; Xu J; Zhang B; Xu W; Liu J; Shi S; Liu L; Liu C; Long J; Ni Q; Li M; Yu X
    Mol Cancer; 2014 Aug; 13():187. PubMed ID: 25103363
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Profilin-1 deficiency leads to SMAD3 upregulation and impaired 3D outgrowth of breast cancer cells.
    Chakraborty S; Jiang C; Gau D; Oddo M; Ding Z; Vollmer L; Joy M; Schiemann W; Stolz DB; Vogt A; Ghosh S; Roy P
    Br J Cancer; 2018 Oct; 119(9):1106-1117. PubMed ID: 30318519
    [TBL] [Abstract][Full Text] [Related]  

  • 13. C-Terminus of Hsc70-interacting protein regulates profilin1 and breast cancer cell migration.
    Choi YN; Lee SK; Seo TW; Lee JS; Yoo SJ
    Biochem Biophys Res Commun; 2014 Apr; 446(4):1060-6. PubMed ID: 24661873
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca2+ signaling in T24M-based bladder cancer models.
    Frantzi M; Klimou Z; Makridakis M; Zoidakis J; Latosinska A; Borràs DM; Janssen B; Giannopoulou I; Lygirou V; Lazaris AC; Anagnou NP; Mischak H; Roubelakis MG; Vlahou A
    Oncotarget; 2016 Oct; 7(43):70750-70768. PubMed ID: 27683119
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Profilin-1 downregulation has contrasting effects on early vs late steps of breast cancer metastasis.
    Ding Z; Joy M; Bhargava R; Gunsaulus M; Lakshman N; Miron-Mendoza M; Petroll M; Condeelis J; Wells A; Roy P
    Oncogene; 2014 Apr; 33(16):2065-74. PubMed ID: 23686314
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Guttiferone K suppresses cell motility and metastasis of hepatocellular carcinoma by restoring aberrantly reduced profilin 1.
    Shen K; Xi Z; Xie J; Wang H; Xie C; Lee CS; Fahey P; Dong Q; Xu H
    Oncotarget; 2016 Aug; 7(35):56650-56663. PubMed ID: 27494863
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular insights on context-specific role of profilin-1 in cell migration.
    Ding Z; Bae YH; Roy P
    Cell Adh Migr; 2012; 6(5):442-9. PubMed ID: 23076048
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Subcellular localization and Ser-137 phosphorylation regulate tumor-suppressive activity of profilin-1.
    Diamond MI; Cai S; Boudreau A; Carey CJ; Lyle N; Pappu RV; Swamidass SJ; Bissell M; Piwnica-Worms H; Shao J
    J Biol Chem; 2015 Apr; 290(14):9075-86. PubMed ID: 25681442
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Quantitative proteomics approach to screening of potential diagnostic and therapeutic targets for laryngeal carcinoma.
    Li L; Zhang Z; Wang C; Miao L; Zhang J; Wang J; Jiao B; Zhao S
    PLoS One; 2014; 9(2):e90181. PubMed ID: 24587265
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Profilin 1 potentiates apoptosis induced by staurosporine in cancer cells.
    Yao W; Cai X; Liu C; Qin Y; Cheng H; Ji S; Xu W; Wu C; Chen T; Xu J; Long J; Fang Z; Qu B; Hoth M; Ni Q; Zha X; Yu X
    Curr Mol Med; 2013 Mar; 13(3):417-28. PubMed ID: 23331014
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.