These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 25458601)

  • 1. Discovery of potent KIFC1 inhibitors using a method of integrated high-throughput synthesis and screening.
    Yang B; Lamb ML; Zhang T; Hennessy EJ; Grewal G; Sha L; Zambrowski M; Block MH; Dowling JE; Su N; Wu J; Deegan T; Mikule K; Wang W; Kaspera R; Chuaqui C; Chen H
    J Med Chem; 2014 Dec; 57(23):9958-70. PubMed ID: 25458601
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.
    Wu J; Mikule K; Wang W; Su N; Petteruti P; Gharahdaghi F; Code E; Zhu X; Jacques K; Lai Z; Yang B; Lamb ML; Chuaqui C; Keen N; Chen H
    ACS Chem Biol; 2013 Oct; 8(10):2201-8. PubMed ID: 23895133
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of kinesin motor protein KIFC1 by AZ82 induces multipolar mitosis and apoptosis in prostate cancer cell.
    Parvin A; Hao SL; Tan FQ; Yang WX
    Gene; 2020 Nov; 760():144989. PubMed ID: 32717307
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fission yeast cells overproducing HSET/KIFC1 provides a useful tool for identification and evaluation of human kinesin-14 inhibitors.
    Yukawa M; Yamauchi T; Kurisawa N; Ahmed S; Kimura KI; Toda T
    Fungal Genet Biol; 2018 Jul; 116():33-41. PubMed ID: 29684553
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.
    Park HW; Ma Z; Zhu H; Jiang S; Robinson RC; Endow SA
    Sci Rep; 2017 Nov; 7(1):15121. PubMed ID: 29123223
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of a novel inhibitor of kinesin-like protein KIFC1.
    Zhang W; Zhai L; Wang Y; Boohaker RJ; Lu W; Gupta VV; Padmalayam I; Bostwick RJ; White EL; Ross LJ; Maddry J; Ananthan S; Augelli-Szafran CE; Suto MJ; Xu B; Li R; Li Y
    Biochem J; 2016 Apr; 473(8):1027-35. PubMed ID: 26846349
    [TBL] [Abstract][Full Text] [Related]  

  • 7. KIFC1: a promising chemotherapy target for cancer treatment?
    Xiao YX; Yang WX
    Oncotarget; 2016 Jul; 7(30):48656-48670. PubMed ID: 27102297
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of 2-(3-Benzamidopropanamido)thiazole-5-carboxylate Inhibitors of the Kinesin HSET (KIFC1) and the Development of Cellular Target Engagement Probes.
    Saint-Dizier F; Matthews TP; Gregson AM; Prevet H; McHardy T; Colombano G; Saville H; Rowlands M; Ewens C; McAndrew PC; Tomlin K; Guillotin D; Mak GW; Drosopoulos K; Poursaitidis I; Burke R; van Montfort R; Linardopoulos S; Collins I
    J Med Chem; 2023 Feb; 66(4):2622-2645. PubMed ID: 36749938
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Computational benchmarking of putative KIFC1 inhibitors.
    Sharma N; Setiawan D; Hamelberg D; Narayan R; Aneja R
    Med Res Rev; 2023 Mar; 43(2):293-318. PubMed ID: 36104980
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kinesin Family Member C1 (KIFC1/HSET): A Potential Actionable Biomarker of Early Stage Breast Tumorigenesis and Progression of High-Risk Lesions.
    Wright N; Gong Z; Kittles R; Natarajan R; Jovanovic-Talisman T; Rida P; LaBarge M; Seewaldt V
    J Pers Med; 2021 Dec; 11(12):. PubMed ID: 34945833
    [TBL] [Abstract][Full Text] [Related]  

  • 11. KIFC1 is a novel potential therapeutic target for breast cancer.
    Li Y; Lu W; Chen D; Boohaker RJ; Zhai L; Padmalayam I; Wennerberg K; Xu B; Zhang W
    Cancer Biol Ther; 2015; 16(9):1316-22. PubMed ID: 26177331
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5.
    Schiemann K; Finsinger D; Zenke F; Amendt C; Knöchel T; Bruge D; Buchstaller HP; Emde U; Stähle W; Anzali S
    Bioorg Med Chem Lett; 2010 Mar; 20(5):1491-5. PubMed ID: 20149654
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bis(hetero)aryl derivatives as unique kinesin spindle protein inhibitors.
    Matsuno K; Sawada J; Sugimoto M; Ogo N; Asai A
    Bioorg Med Chem Lett; 2009 Feb; 19(4):1058-61. PubMed ID: 19167222
    [TBL] [Abstract][Full Text] [Related]  

  • 14. C-terminal kinesin motor KIFC1 participates in facilitating proper cell division of human seminoma.
    Xiao YX; Shen HQ; She ZY; Sheng L; Chen QQ; Chu YL; Tan FQ; Yang WX
    Oncotarget; 2017 Sep; 8(37):61373-61384. PubMed ID: 28977870
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prognostic and clinicopathological significance of kinesin family member C1 in various cancers: A meta-analysis.
    Sun Y; Zhang Y; Lang Z; Huang J; Zou Z
    Medicine (Baltimore); 2019 Oct; 98(40):e17346. PubMed ID: 31577729
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Kinesin family member C1 accelerates bladder cancer cell proliferation and induces epithelial-mesenchymal transition via Akt/GSK3β signaling.
    Xiao KH; Teng K; Ye YL; Tan L; Chen MK; Liang HT; Feng ZH; Duan JL; Deng MH; Wei WS; Luo JH; Qin ZK; Xie D
    Cancer Sci; 2019 Sep; 110(9):2822-2833. PubMed ID: 31278883
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The discovery of tetrahydro-beta-carbolines as inhibitors of the kinesin Eg5.
    Barsanti PA; Wang W; Ni ZJ; Duhl D; Brammeier N; Martin E; Bussiere D; Walter AO
    Bioorg Med Chem Lett; 2010 Jan; 20(1):157-60. PubMed ID: 19945875
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Export of membrane proteins from the Golgi complex to the primary cilium requires the kinesin motor, KIFC1.
    Lee SH; Joo K; Jung EJ; Hong H; Seo J; Kim J
    FASEB J; 2018 Feb; 32(2):957-968. PubMed ID: 29042452
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The overexpression of KIFC1 was associated with the proliferation and prognosis of non-small cell lung cancer.
    Liu Y; Zhan P; Zhou Z; Xing Z; Zhu S; Ma C; Li Q; Zhu Q; Miao Y; Zhang J; Lv T; Song Y
    J Thorac Dis; 2016 Oct; 8(10):2911-2923. PubMed ID: 27867568
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and evaluation of MCH receptor 1 antagonists--Part I: Optimization of HTS hits towards an in vivo efficacious tool compound BI 414.
    Müller SG; Heckel A; Kley JT; Lehmann T; Lustenberger P; Oost T; Roth GJ; Rudolf K; Arndt K; Lenter M; Lotz RR; Maier GM; Markert M; Schindler M; Stenkamp D
    Bioorg Med Chem Lett; 2015 Aug; 25(16):3264-9. PubMed ID: 26112443
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.