BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 25458704)

  • 1. IRE1 impairs insulin signaling transduction of fructose-fed mice via JNK independent of excess lipid.
    Sun RQ; Wang H; Zeng XY; Chan SM; Li SP; Jo E; Leung SL; Molero JC; Ye JM
    Biochim Biophys Acta; 2015 Jan; 1852(1):156-65. PubMed ID: 25458704
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance.
    Ren LP; Chan SM; Zeng XY; Laybutt DR; Iseli TJ; Sun RQ; Kraegen EW; Cooney GJ; Turner N; Ye JM
    PLoS One; 2012; 7(2):e30816. PubMed ID: 22355328
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of PPARα ameliorates hepatic insulin resistance and steatosis in high fructose-fed mice despite increased endoplasmic reticulum stress.
    Chan SM; Sun RQ; Zeng XY; Choong ZH; Wang H; Watt MJ; Ye JM
    Diabetes; 2013 Jun; 62(6):2095-105. PubMed ID: 23349482
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Restoration of autophagy alleviates hepatic ER stress and impaired insulin signalling transduction in high fructose-fed male mice.
    Wang H; Sun RQ; Zeng XY; Zhou X; Li S; Jo E; Molero JC; Ye JM
    Endocrinology; 2015 Jan; 156(1):169-81. PubMed ID: 25343276
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice.
    Latreille M; Laberge MK; Bourret G; Yamani L; Larose L
    Am J Physiol Endocrinol Metab; 2011 Mar; 300(3):E423-34. PubMed ID: 20587749
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice.
    Jurczak MJ; Lee AH; Jornayvaz FR; Lee HY; Birkenfeld AL; Guigni BA; Kahn M; Samuel VT; Glimcher LH; Shulman GI
    J Biol Chem; 2012 Jan; 287(4):2558-67. PubMed ID: 22128176
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Similar changes in muscle lipid metabolism are induced by chronic high-fructose feeding and high-fat feeding in C57BL/J6 mice.
    Song GY; Ren LP; Chen SC; Wang C; Liu N; Wei LM; Li F; Sun W; Peng LB; Tang Y
    Clin Exp Pharmacol Physiol; 2012 Dec; 39(12):1011-8. PubMed ID: 23039229
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hepatospecific effects of fructose on c-jun NH2-terminal kinase: implications for hepatic insulin resistance.
    Wei Y; Pagliassotti MJ
    Am J Physiol Endocrinol Metab; 2004 Nov; 287(5):E926-33. PubMed ID: 15198936
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes.
    Gao Z; Zhang X; Zuberi A; Hwang D; Quon MJ; Lefevre M; Ye J
    Mol Endocrinol; 2004 Aug; 18(8):2024-34. PubMed ID: 15143153
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Infusion of beta-endorphin improves insulin resistance in fructose-fed rats.
    Su CF; Chang YY; Pai HH; Liu IM; Lo CY; Cheng JT
    Horm Metab Res; 2004 Aug; 36(8):571-7. PubMed ID: 15326568
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IRE1α and TRB3 do not contribute to the disruption of proximal insulin signaling caused by palmitate in C2C12 myotubes.
    Pierre N; Fernández-Verdejo R; Regnier P; Vanmechelen S; Demeulder B; Francaux M
    Cell Biol Int; 2016 Jan; 40(1):91-9. PubMed ID: 26337904
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Acylated ghrelin induces but deacylated ghrelin prevents hepatic steatosis and insulin resistance in lean rats: Effects on DAG/ PKC/JNK pathway.
    Dallak MA
    Biomed Pharmacother; 2018 Sep; 105():299-311. PubMed ID: 29860222
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protective effect of quercetin on lead-induced oxidative stress and endoplasmic reticulum stress in rat liver via the IRE1/JNK and PI3K/Akt pathway.
    Liu CM; Zheng GH; Ming QL; Sun JM; Cheng C
    Free Radic Res; 2013 Mar; 47(3):192-201. PubMed ID: 23249147
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genistein sensitizes hepatic insulin signaling and modulates lipid regulatory genes through p70 ribosomal S6 kinase-1 inhibition in high-fat-high-fructose diet-fed mice.
    Arunkumar E; Karthik D; Anuradha CV
    Pharm Biol; 2013 Jul; 51(7):815-24. PubMed ID: 23627466
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fructose supplementation impairs rat liver autophagy through mTORC activation without inducing endoplasmic reticulum stress.
    Baena M; Sangüesa G; Hutter N; Sánchez RM; Roglans N; Laguna JC; Alegret M
    Biochim Biophys Acta; 2015 Feb; 1851(2):107-16. PubMed ID: 25463011
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: role of IRS phosphorylation.
    Zhang Q; Carter EA; Ma BY; White M; Fischman AJ; Tompkins RG
    Life Sci; 2005 Oct; 77(24):3068-77. PubMed ID: 15982669
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance.
    Vinayagamoorthi R; Bobby Z; Sridhar MG
    J Endocrinol; 2008 May; 197(2):287-96. PubMed ID: 18434358
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fructose supplementation worsens the deleterious effects of short-term high-fat feeding on hepatic steatosis and lipid metabolism in adult rats.
    Crescenzo R; Bianco F; Coppola P; Mazzoli A; Tussellino M; Carotenuto R; Liverini G; Iossa S
    Exp Physiol; 2014 Sep; 99(9):1203-13. PubMed ID: 24972835
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.
    Andreozzi F; Laratta E; Sciacqua A; Perticone F; Sesti G
    Circ Res; 2004 May; 94(9):1211-8. PubMed ID: 15044323
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sequential phosphorylation of insulin receptor substrate-2 by glycogen synthase kinase-3 and c-Jun NH2-terminal kinase plays a role in hepatic insulin signaling.
    Sharfi H; Eldar-Finkelman H
    Am J Physiol Endocrinol Metab; 2008 Feb; 294(2):E307-15. PubMed ID: 18029441
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.