These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

485 related articles for article (PubMed ID: 25458842)

  • 1. Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport.
    Yang C; Ko B; Hensley CT; Jiang L; Wasti AT; Kim J; Sudderth J; Calvaruso MA; Lumata L; Mitsche M; Rutter J; Merritt ME; DeBerardinis RJ
    Mol Cell; 2014 Nov; 56(3):414-424. PubMed ID: 25458842
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis.
    Tompkins SC; Sheldon RD; Rauckhorst AJ; Noterman MF; Solst SR; Buchanan JL; Mapuskar KA; Pewa AD; Gray LR; Oonthonpan L; Sharma A; Scerbo DA; Dupuy AJ; Spitz DR; Taylor EB
    Cell Rep; 2019 Sep; 28(10):2608-2619.e6. PubMed ID: 31484072
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Embryonic Lethality of Mitochondrial Pyruvate Carrier 1 Deficient Mouse Can Be Rescued by a Ketogenic Diet.
    Vanderperre B; Herzig S; Krznar P; Hörl M; Ammar Z; Montessuit S; Pierredon S; Zamboni N; Martinou JC
    PLoS Genet; 2016 May; 12(5):e1006056. PubMed ID: 27176894
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of substrate utilization by the mitochondrial pyruvate carrier.
    Vacanti NM; Divakaruni AS; Green CR; Parker SJ; Henry RR; Ciaraldi TP; Murphy AN; Metallo CM
    Mol Cell; 2014 Nov; 56(3):425-435. PubMed ID: 25458843
    [TBL] [Abstract][Full Text] [Related]  

  • 5. c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate.
    Edmunds LR; Sharma L; Kang A; Lu J; Vockley J; Basu S; Uppala R; Goetzman ES; Beck ME; Scott D; Prochownik EV
    J Biol Chem; 2014 Sep; 289(36):25382-92. PubMed ID: 25053415
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling.
    Yang C; Sudderth J; Dang T; Bachoo RM; McDonald JG; DeBerardinis RJ
    Cancer Res; 2009 Oct; 69(20):7986-93. PubMed ID: 19826036
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolic and mind shifts: from glucose to glutamine and acetate addictions in cancer.
    Corbet C; Feron O
    Curr Opin Clin Nutr Metab Care; 2015 Jul; 18(4):346-53. PubMed ID: 26001655
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer.
    Bader DA; Hartig SM; Putluri V; Foley C; Hamilton MP; Smith EA; Saha PK; Panigrahi A; Walker C; Zong L; Martini-Stoica H; Chen R; Rajapakshe K; Coarfa C; Sreekumar A; Mitsiades N; Bankson JA; Ittmann MM; O'Malley BW; Putluri N; McGuire SE
    Nat Metab; 2019 Jan; 1(1):70-85. PubMed ID: 31198906
    [TBL] [Abstract][Full Text] [Related]  

  • 9. THE EFFECTS OF ADENINE NUCLEOTIDES ON PYRUVATE METABOLISM IN RAT LIVER.
    BERRY MN
    Biochem J; 1965 Jun; 95(3):587-96. PubMed ID: 14342491
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cardiolipin-induced activation of pyruvate dehydrogenase links mitochondrial lipid biosynthesis to TCA cycle function.
    Li Y; Lou W; Raja V; Denis S; Yu W; Schmidtke MW; Reynolds CA; Schlame M; Houtkooper RH; Greenberg ML
    J Biol Chem; 2019 Jul; 294(30):11568-11578. PubMed ID: 31186346
    [TBL] [Abstract][Full Text] [Related]  

  • 11. STAT3 Undergoes Acetylation-dependent Mitochondrial Translocation to Regulate Pyruvate Metabolism.
    Xu YS; Liang JJ; Wang Y; Zhao XJ; Xu L; Xu YY; Zou QC; Zhang JM; Tu CE; Cui YG; Sun WH; Huang C; Yang JH; Chin YE
    Sci Rep; 2016 Dec; 6():39517. PubMed ID: 28004755
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Berberine Reduces Pyruvate-driven Hepatic Glucose Production by Limiting Mitochondrial Import of Pyruvate through Mitochondrial Pyruvate Carrier 1.
    Li A; Liu Q; Li Q; Liu B; Yang Y; Zhang N
    EBioMedicine; 2018 Aug; 34():243-255. PubMed ID: 30093307
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reductive carboxylation supports growth in tumour cells with defective mitochondria.
    Mullen AR; Wheaton WW; Jin ES; Chen PH; Sullivan LB; Cheng T; Yang Y; Linehan WM; Chandel NS; DeBerardinis RJ
    Nature; 2011 Nov; 481(7381):385-8. PubMed ID: 22101431
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of mitochondrial pyruvate transport by zaprinast causes massive accumulation of aspartate at the expense of glutamate in the retina.
    Du J; Cleghorn WM; Contreras L; Lindsay K; Rountree AM; Chertov AO; Turner SJ; Sahaboglu A; Linton J; Sadilek M; Satrústegui J; Sweet IR; Paquet-Durand F; Hurley JB
    J Biol Chem; 2013 Dec; 288(50):36129-40. PubMed ID: 24187136
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dysfunctional TCA-Cycle Metabolism in Glutamate Dehydrogenase Deficient Astrocytes.
    Nissen JD; Pajęcka K; Stridh MH; Skytt DM; Waagepetersen HS
    Glia; 2015 Dec; 63(12):2313-26. PubMed ID: 26221781
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer.
    Park S; Safi R; Liu X; Baldi R; Liu W; Liu J; Locasale JW; Chang CY; McDonnell DP
    Cell Rep; 2019 Jun; 27(12):3587-3601.e4. PubMed ID: 31216477
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glutamine Oxidation Is Indispensable for Survival of Human Pluripotent Stem Cells.
    Tohyama S; Fujita J; Hishiki T; Matsuura T; Hattori F; Ohno R; Kanazawa H; Seki T; Nakajima K; Kishino Y; Okada M; Hirano A; Kuroda T; Yasuda S; Sato Y; Yuasa S; Sano M; Suematsu M; Fukuda K
    Cell Metab; 2016 Apr; 23(4):663-74. PubMed ID: 27050306
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The mitochondrial pyruvate carrier (MPC) complex mediates one of three pyruvate-supplying pathways that sustain Arabidopsis respiratory metabolism.
    Le XH; Lee CP; Millar AH
    Plant Cell; 2021 Aug; 33(8):2776-2793. PubMed ID: 34137858
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pyruvate carboxylase is required for glutamine-independent growth of tumor cells.
    Cheng T; Sudderth J; Yang C; Mullen AR; Jin ES; Matés JM; DeBerardinis RJ
    Proc Natl Acad Sci U S A; 2011 May; 108(21):8674-9. PubMed ID: 21555572
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells.
    Le A; Lane AN; Hamaker M; Bose S; Gouw A; Barbi J; Tsukamoto T; Rojas CJ; Slusher BS; Zhang H; Zimmerman LJ; Liebler DC; Slebos RJ; Lorkiewicz PK; Higashi RM; Fan TW; Dang CV
    Cell Metab; 2012 Jan; 15(1):110-21. PubMed ID: 22225880
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.