303 related articles for article (PubMed ID: 25458911)
1. Histone deacetylase 6 inhibition impairs effector CD8 T-cell functions during skin inflammation.
Tsuji G; Okiyama N; Villarroel VA; Katz SI
J Allergy Clin Immunol; 2015 May; 135(5):1228-39. PubMed ID: 25458911
[TBL] [Abstract][Full Text] [Related]
2. HDAC6 selective inhibition of melanoma patient T-cells augments anti-tumor characteristics.
Laino AS; Betts BC; Veerapathran A; Dolgalev I; Sarnaik A; Quayle SN; Jones SS; Weber JS; Woods DM
J Immunother Cancer; 2019 Feb; 7(1):33. PubMed ID: 30728070
[TBL] [Abstract][Full Text] [Related]
3. HDAC6 Inhibition Alleviates CLL-Induced T-Cell Dysfunction and Enhances Immune Checkpoint Blockade Efficacy in the Eμ-TCL1 Model.
Maharaj K; Powers JJ; Mediavilla-Varela M; Achille A; Gamal W; Quayle S; Jones SS; Sahakian E; Pinilla-Ibarz J
Front Immunol; 2020; 11():590072. PubMed ID: 33329575
[TBL] [Abstract][Full Text] [Related]
4. Histone deacetylase 6 inhibitor ACY-1215 protects against experimental acute liver failure by regulating the TLR4-MAPK/NF-κB pathway.
Zhang WB; Zhang HY; Jiao FZ; Wang LW; Zhang H; Gong ZJ
Biomed Pharmacother; 2018 Jan; 97():818-824. PubMed ID: 29112935
[TBL] [Abstract][Full Text] [Related]
5. Combination of a Histone Deacetylase 6 Inhibitor and a Somatostatin Receptor Agonist Synergistically Reduces Hepatorenal Cystogenesis in an Animal Model of Polycystic Liver Disease.
Lorenzo Pisarello M; Masyuk TV; Gradilone SA; Masyuk AI; Ding JF; Lee PY; LaRusso NF
Am J Pathol; 2018 Apr; 188(4):981-994. PubMed ID: 29366679
[TBL] [Abstract][Full Text] [Related]
6. The structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity.
Negmeldin AT; Knoff JR; Pflum MKH
Eur J Med Chem; 2018 Jan; 143():1790-1806. PubMed ID: 29150330
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of HDAC6 modifies tau inclusion body formation and impairs autophagic clearance.
Leyk J; Goldbaum O; Noack M; Richter-Landsberg C
J Mol Neurosci; 2015 Apr; 55(4):1031-46. PubMed ID: 25434725
[TBL] [Abstract][Full Text] [Related]
8. ACY 1215, a histone deacetylase 6 inhibitor, inhibits cancer cell growth in melanoma.
Wang F; Zhong BW; Zhao ZR
J Biol Regul Homeost Agents; 2018; 32(4):851-858. PubMed ID: 30043566
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of Histone Deacetylase 6 Reveals a Potent Immunosuppressant Effect in Models of Transplantation.
Ellis JD; Neil DA; Inston NG; Jenkinson E; Drayson MT; Hampson P; Shuttleworth SJ; Ready AR; Cobbold M
Transplantation; 2016 Aug; 100(8):1667-74. PubMed ID: 27222932
[TBL] [Abstract][Full Text] [Related]
10. Selective Histone Deacetylase 6 Inhibition Normalizes B Cell Activation and Germinal Center Formation in a Model of Systemic Lupus Erythematosus.
Ren J; Catalina MD; Eden K; Liao X; Read KA; Luo X; McMillan RP; Hulver MW; Jarpe M; Bachali P; Grammer AC; Lipsky PE; Reilly CM
Front Immunol; 2019; 10():2512. PubMed ID: 31708928
[TBL] [Abstract][Full Text] [Related]
11. Reduction of graft-versus-host disease by histone deacetylase inhibitor suberonylanilide hydroxamic acid is associated with modulation of inflammatory cytokine milieu and involves inhibition of STAT1.
Leng C; Gries M; Ziegler J; Lokshin A; Mascagni P; Lentzsch S; Mapara MY
Exp Hematol; 2006 Jun; 34(6):776-87. PubMed ID: 16728283
[TBL] [Abstract][Full Text] [Related]
12. Tubastatin A suppresses renal fibrosis via regulation of epigenetic histone modification and Smad3-dependent fibrotic genes.
Choi SY; Ryu Y; Kee HJ; Cho SN; Kim GR; Cho JY; Kim HS; Kim IK; Jeong MH
Vascul Pharmacol; 2015 Sep; 72():130-40. PubMed ID: 25921924
[TBL] [Abstract][Full Text] [Related]
13. Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells.
de Zoeten EF; Wang L; Butler K; Beier UH; Akimova T; Sai H; Bradner JE; Mazitschek R; Kozikowski AP; Matthias P; Hancock WW
Mol Cell Biol; 2011 May; 31(10):2066-78. PubMed ID: 21444725
[TBL] [Abstract][Full Text] [Related]
14. Dual Targeting of Protein Degradation Pathways with the Selective HDAC6 Inhibitor ACY-1215 and Bortezomib Is Synergistic in Lymphoma.
Amengual JE; Johannet P; Lombardo M; Zullo K; Hoehn D; Bhagat G; Scotto L; Jirau-Serrano X; Radeski D; Heinen J; Jiang H; Cremers S; Zhang Y; Jones S; O'Connor OA
Clin Cancer Res; 2015 Oct; 21(20):4663-75. PubMed ID: 26116270
[TBL] [Abstract][Full Text] [Related]
15. Tubastatin, a selective histone deacetylase 6 inhibitor shows anti-inflammatory and anti-rheumatic effects.
Vishwakarma S; Iyer LR; Muley M; Singh PK; Shastry A; Saxena A; Kulathingal J; Vijaykanth G; Raghul J; Rajesh N; Rathinasamy S; Kachhadia V; Kilambi N; Rajgopal S; Balasubramanian G; Narayanan S
Int Immunopharmacol; 2013 May; 16(1):72-8. PubMed ID: 23541634
[TBL] [Abstract][Full Text] [Related]
16. Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma.
Santo L; Hideshima T; Kung AL; Tseng JC; Tamang D; Yang M; Jarpe M; van Duzer JH; Mazitschek R; Ogier WC; Cirstea D; Rodig S; Eda H; Scullen T; Canavese M; Bradner J; Anderson KC; Jones SS; Raje N
Blood; 2012 Mar; 119(11):2579-89. PubMed ID: 22262760
[TBL] [Abstract][Full Text] [Related]
17. Cathepsin S Activity Controls Injury-Related Vascular Repair in Mice via the TLR2-Mediated p38MAPK and PI3K-Akt/p-HDAC6 Signaling Pathway.
Wu H; Cheng XW; Hu L; Takeshita K; Hu C; Du Q; Li X; Zhu E; Huang Z; Yisireyili M; Zhao G; Piao L; Inoue A; Jiang H; Lei Y; Zhang X; Liu S; Dai Q; Kuzuya M; Shi GP; Murohara T
Arterioscler Thromb Vasc Biol; 2016 Aug; 36(8):1549-57. PubMed ID: 27365406
[TBL] [Abstract][Full Text] [Related]
18. Antidepressant-like properties of novel HDAC6-selective inhibitors with improved brain bioavailability.
Jochems J; Boulden J; Lee BG; Blendy JA; Jarpe M; Mazitschek R; Van Duzer JH; Jones S; Berton O
Neuropsychopharmacology; 2014 Jan; 39(2):389-400. PubMed ID: 23954848
[TBL] [Abstract][Full Text] [Related]
19. HDAC6 is overexpressed in cystic cholangiocytes and its inhibition reduces cystogenesis.
Gradilone SA; Habringer S; Masyuk TV; Howard BN; Masyuk AI; Larusso NF
Am J Pathol; 2014 Mar; 184(3):600-8. PubMed ID: 24434010
[TBL] [Abstract][Full Text] [Related]
20. An inhibitor of histone deacetylase 6 activity, ACY-1215, reduces cAMP and cyst growth in polycystic kidney disease.
Yanda MK; Liu Q; Cebotaru L
Am J Physiol Renal Physiol; 2017 Oct; 313(4):F997-F1004. PubMed ID: 28747357
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
