These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Inhibition of ATR-dependent feedback activation of Chk1 sensitises cancer cells to Chk1 inhibitor monotherapy. Massey AJ Cancer Lett; 2016 Dec; 383(1):41-52. PubMed ID: 27693461 [TBL] [Abstract][Full Text] [Related]
3. dSTORM microscopy evidences in HeLa cells clustered and scattered γH2AX nanofoci sensitive to ATM, DNA-PK, and ATR kinase inhibitors. Liddle P; Jara-Wilde J; Lafon-Hughes L; Castro I; Härtel S; Folle G Mol Cell Biochem; 2020 Oct; 473(1-2):77-91. PubMed ID: 32638256 [TBL] [Abstract][Full Text] [Related]
4. A majority of human melanoma cell lines exhibits an S phase-specific defect in excision of UV-induced DNA photoproducts. Bélanger F; Rajotte V; Drobetsky EA PLoS One; 2014; 9(1):e85294. PubMed ID: 24416382 [TBL] [Abstract][Full Text] [Related]
5. Perturbed gap-filling synthesis in nucleotide excision repair causes histone H2AX phosphorylation in human quiescent cells. Matsumoto M; Yaginuma K; Igarashi A; Imura M; Hasegawa M; Iwabuchi K; Date T; Mori T; Ishizaki K; Yamashita K; Inobe M; Matsunaga T J Cell Sci; 2007 Mar; 120(Pt 6):1104-12. PubMed ID: 17327276 [TBL] [Abstract][Full Text] [Related]
6. Ataxia telangiectasia-mutated-Rad3-related DNA damage checkpoint signaling pathway triggered by hepatitis B virus infection. Zhao F; Hou NB; Yang XL; He X; Liu Y; Zhang YH; Wei CW; Song T; Li L; Ma QJ; Zhong H World J Gastroenterol; 2008 Oct; 14(40):6163-70. PubMed ID: 18985806 [TBL] [Abstract][Full Text] [Related]
7. ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation. Wei F; Xie Y; He L; Tao L; Tang D Cell Signal; 2011 Jan; 23(1):259-68. PubMed ID: 20840867 [TBL] [Abstract][Full Text] [Related]
8. Contribution of ATM and ATR to the resistance of glioblastoma and malignant melanoma cells to the methylating anticancer drug temozolomide. Eich M; Roos WP; Nikolova T; Kaina B Mol Cancer Ther; 2013 Nov; 12(11):2529-40. PubMed ID: 23960094 [TBL] [Abstract][Full Text] [Related]
9. Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage. Ha K; Fiskus W; Rao R; Balusu R; Venkannagari S; Nalabothula NR; Bhalla KN Mol Cancer Ther; 2011 Jul; 10(7):1194-206. PubMed ID: 21566061 [TBL] [Abstract][Full Text] [Related]
10. Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio-resistance in breast cancer. Alsubhi N; Middleton F; Abdel-Fatah TM; Stephens P; Doherty R; Arora A; Moseley PM; Chan SY; Aleskandarany MA; Green AR; Rakha EA; Ellis IO; Martin SG; Curtin NJ; Madhusudan S Mol Oncol; 2016 Feb; 10(2):213-23. PubMed ID: 26459098 [TBL] [Abstract][Full Text] [Related]
11. UV-induced G2 checkpoint depends on p38 MAPK and minimal activation of ATR-Chk1 pathway. Warmerdam DO; Brinkman EK; Marteijn JA; Medema RH; Kanaar R; Smits VA J Cell Sci; 2013 May; 126(Pt 9):1923-30. PubMed ID: 23447674 [TBL] [Abstract][Full Text] [Related]
12. Effects of hydroxyurea and aphidicolin on phosphorylation of ataxia telangiectasia mutated on Ser 1981 and histone H2AX on Ser 139 in relation to cell cycle phase and induction of apoptosis. Kurose A; Tanaka T; Huang X; Traganos F; Dai W; Darzynkiewicz Z Cytometry A; 2006 Apr; 69(4):212-21. PubMed ID: 16528719 [TBL] [Abstract][Full Text] [Related]
14. ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle. Ray A; Blevins C; Wani G; Wani AA PLoS One; 2016; 11(7):e0159344. PubMed ID: 27442013 [TBL] [Abstract][Full Text] [Related]
15. Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells. Tyagi A; Singh RP; Agarwal C; Siriwardana S; Sclafani RA; Agarwal R Carcinogenesis; 2005 Nov; 26(11):1978-87. PubMed ID: 15975956 [TBL] [Abstract][Full Text] [Related]
16. ATR mediates cisplatin resistance in 3D-cultured breast cancer cells via translesion DNA synthesis modulation. Gomes LR; Rocha CRR; Martins DJ; Fiore APZP; Kinker GS; Bruni-Cardoso A; Menck CFM Cell Death Dis; 2019 Jun; 10(6):459. PubMed ID: 31189884 [TBL] [Abstract][Full Text] [Related]
17. Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage. Syljuåsen RG; Sørensen CS; Hansen LT; Fugger K; Lundin C; Johansson F; Helleday T; Sehested M; Lukas J; Bartek J Mol Cell Biol; 2005 May; 25(9):3553-62. PubMed ID: 15831461 [TBL] [Abstract][Full Text] [Related]
18. Molecular Pathways: Targeting ATR in Cancer Therapy. Karnitz LM; Zou L Clin Cancer Res; 2015 Nov; 21(21):4780-5. PubMed ID: 26362996 [TBL] [Abstract][Full Text] [Related]
19. H2AX phosphorylation after UV irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinase. Hanasoge S; Ljungman M Carcinogenesis; 2007 Nov; 28(11):2298-304. PubMed ID: 17615256 [TBL] [Abstract][Full Text] [Related]
20. Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors. Wang H; Wang M; Wang H; Böcker W; Iliakis G J Cell Physiol; 2005 Feb; 202(2):492-502. PubMed ID: 15389585 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]