BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 25461330)

  • 1. Discovery of novel indole derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase.
    Bie J; Liu S; Li Z; Mu Y; Xu B; Shen Z
    Eur J Med Chem; 2015 Jan; 90():394-405. PubMed ID: 25461330
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and biological evaluation of 7-nitro-1H-indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase.
    Bie J; Liu S; Zhou J; Xu B; Shen Z
    Bioorg Med Chem; 2014 Mar; 22(6):1850-62. PubMed ID: 24530031
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of novel allosteric site and covalent inhibitors of FBPase with potent hypoglycemic effects.
    Huang Y; Wei L; Han X; Chen H; Ren Y; Xu Y; Song R; Rao L; Su C; Peng C; Feng L; Wan J
    Eur J Med Chem; 2019 Dec; 184():111749. PubMed ID: 31589992
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site.
    Wright SW; Carlo AA; Danley DE; Hageman DL; Karam GA; Mansour MN; McClure LD; Pandit J; Schulte GK; Treadway JL; Wang IK; Bauer PH
    Bioorg Med Chem Lett; 2003 Jun; 13(12):2055-8. PubMed ID: 12781194
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of
    Zhou J; Bie J; Wang X; Liu Q; Li R; Chen H; Hu J; Cao H; Ji W; Li Y; Liu S; Shen Z; Xu B
    J Med Chem; 2020 Sep; 63(18):10307-10329. PubMed ID: 32820629
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and structure-activity relationship of non-phosphorus-based fructose-1,6-bisphosphatase inhibitors: 2,5-Diphenyl-1,3,4-oxadiazoles.
    Liao BR; He HB; Yang LL; Gao LX; Chang L; Tang J; Li JY; Li J; Yang F
    Eur J Med Chem; 2014 Aug; 83():15-25. PubMed ID: 24946215
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rational design, synthesis, and potency of N-substituted indoles, pyrroles, and triarylpyrazoles as potential fructose 1,6-bisphosphatase inhibitors.
    Rudnitskaya A; Borkin DA; Huynh K; Török B; Stieglitz K
    ChemMedChem; 2010 Mar; 5(3):384-9. PubMed ID: 20069623
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-guided design of AMP mimics that inhibit fructose-1,6-bisphosphatase with high affinity and specificity.
    Erion MD; Dang Q; Reddy MR; Kasibhatla SR; Huang J; Lipscomb WN; van Poelje PD
    J Am Chem Soc; 2007 Dec; 129(50):15480-90. PubMed ID: 18041833
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of potent and specific fructose-1,6-bisphosphatase inhibitors and a series of orally-bioavailable phosphoramidase-sensitive prodrugs for the treatment of type 2 diabetes.
    Dang Q; Kasibhatla SR; Reddy KR; Jiang T; Reddy MR; Potter SC; Fujitaki JM; van Poelje PD; Huang J; Lipscomb WN; Erion MD
    J Am Chem Soc; 2007 Dec; 129(50):15491-502. PubMed ID: 18041834
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Recent advance in the discovery of allosteric inhibitors binding to the AMP site of fructose-1,6-bisphosphatase].
    Li ZM; Bie JB; Song HR; Xu BL
    Yao Xue Xue Bao; 2011 Nov; 46(11):1291-300. PubMed ID: 22260018
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode.
    von Geldern TW; Lai C; Gum RJ; Daly M; Sun C; Fry EH; Abad-Zapatero C
    Bioorg Med Chem Lett; 2006 Apr; 16(7):1811-5. PubMed ID: 16442285
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase.
    Lai C; Gum RJ; Daly M; Fry EH; Hutchins C; Abad-Zapatero C; von Geldern TW
    Bioorg Med Chem Lett; 2006 Apr; 16(7):1807-10. PubMed ID: 16446092
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, SAR, and X-ray structure of tricyclic compounds as potent FBPase inhibitors.
    Tsukada T; Takahashi M; Takemoto T; Kanno O; Yamane T; Kawamura S; Nishi T
    Bioorg Med Chem Lett; 2009 Oct; 19(20):5909-12. PubMed ID: 19762234
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ligand-based designing, in silico screening, and biological evaluation of new potent fructose-1,6-bisphosphatase (FBPase) inhibitors.
    Tayyem RF; Zalloum HM; Elmaghrabi MR; Yousef AM; Mubarak MS
    Eur J Med Chem; 2012 Oct; 56():70-95. PubMed ID: 22960695
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In silico screening of a novel scaffold for fructose-1,6-bisphosatase (FBPase) inhibitors.
    Huang Y; Chi B; Xu Y; Song R; Wei L; Rao L; Feng L; Ren Y; Wan J
    J Mol Graph Model; 2019 Jan; 86():142-148. PubMed ID: 30366190
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Allosteric inhibition of fructose-1,6-bisphosphatase by anilinoquinazolines.
    Wright SW; Hageman DL; McClure LD; Carlo AA; Treadway JL; Mathiowetz AM; Withka JM; Bauer PH
    Bioorg Med Chem Lett; 2001 Jan; 11(1):17-21. PubMed ID: 11140724
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biological evaluation and SAR analysis of novel covalent inhibitors against fructose-1,6-bisphosphatase.
    Han X; Huang Y; Wei L; Chen H; Guo Y; Tang Z; Hu W; Xia Q; Wang Q; Yan J; Ren Y
    Bioorg Med Chem; 2020 Sep; 28(18):115624. PubMed ID: 32828433
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-based design and synthesis of novel dual-target inhibitors against cyanobacterial fructose-1,6-bisphosphate aldolase and fructose-1,6-bisphosphatase.
    Li D; Han X; Tu Q; Feng L; Wu D; Sun Y; Chen H; Li Y; Ren Y; Wan J
    J Agric Food Chem; 2013 Aug; 61(31):7453-61. PubMed ID: 23889687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fructose-1,6-bisphosphatase Inhibitors. 2. Design, synthesis, and structure-activity relationship of a series of phosphonic acid containing benzimidazoles that function as 5'-adenosinemonophosphate (AMP) mimics.
    Dang Q; Kasibhatla SR; Xiao W; Liu Y; Dare J; Taplin F; Reddy KR; Scarlato GR; Gibson T; van Poelje PD; Potter SC; Erion MD
    J Med Chem; 2010 Jan; 53(1):441-51. PubMed ID: 20055427
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Orally active aminopyridines as inhibitors of tetrameric fructose-1,6-bisphosphatase.
    Hebeisen P; Haap W; Kuhn B; Mohr P; Wessel HP; Zutter U; Kirchner S; Ruf A; Benz J; Joseph C; Alvarez-Sánchez R; Gubler M; Schott B; Benardeau A; Tozzo E; Kitas E
    Bioorg Med Chem Lett; 2011 Jun; 21(11):3237-42. PubMed ID: 21550236
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.