BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 25463631)

  • 1. Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
    Roland BP; Amrich CG; Kammerer CJ; Stuchul KA; Larsen SB; Rode S; Aslam AA; Heroux A; Wetzel R; VanDemark AP; Palladino MJ
    Biochim Biophys Acta; 2015 Jan; 1852(1):61-9. PubMed ID: 25463631
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.
    Segal J; Mülleder M; Krüger A; Adler T; Scholze-Wittler M; Becker L; Calzada-Wack J; Garrett L; Hölter SM; Rathkolb B; Rozman J; Racz I; Fischer R; Busch DH; Neff F; Klingenspor M; Klopstock T; Grüning NM; Michel S; Lukaszewska-McGreal B; Voigt I; Hartmann L; Timmermann B; Lehrach H; Wolf E; Wurst W; Gailus-Durner V; Fuchs H; H de Angelis M; Schrewe H; Yuneva M; Ralser M
    J Inherit Metab Dis; 2019 Sep; 42(5):839-849. PubMed ID: 31111503
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.
    Roland BP; Richards KR; Hrizo SL; Eicher S; Barile ZJ; Chang TC; Savon G; Bianchi P; Fermo E; Ricerca BM; Tortorolo L; Vockley J; VanDemark AP; Palladino MJ
    Biochim Biophys Acta Mol Basis Dis; 2019 Sep; 1865(9):2257-2266. PubMed ID: 31075491
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics.
    Roland BP; Zeccola AM; Larsen SB; Amrich CG; Talsma AD; Stuchul KA; Heroux A; Levitan ES; VanDemark AP; Palladino MJ
    PLoS Genet; 2016 Mar; 12(3):e1005941. PubMed ID: 27031109
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity.
    Roland BP; Stuchul KA; Larsen SB; Amrich CG; Vandemark AP; Celotto AM; Palladino MJ
    J Cell Sci; 2013 Jul; 126(Pt 14):3151-8. PubMed ID: 23641070
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential effects on enzyme stability and kinetic parameters of mutants related to human triosephosphate isomerase deficiency.
    Cabrera N; Torres-Larios A; García-Torres I; Enríquez-Flores S; Perez-Montfort R
    Biochim Biophys Acta Gen Subj; 2018 Jun; 1862(6):1401-1409. PubMed ID: 29571745
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Triosephosphate isomerase deficiency: Effect of F240L mutation on enzyme structure.
    Romero JM
    Arch Biochem Biophys; 2020 Aug; 689():108473. PubMed ID: 32585311
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The E104D mutation increases the susceptibility of human triosephosphate isomerase to proteolysis. Asymmetric cleavage of the two monomers of the homodimeric enzyme.
    De La Mora-De La Mora I; Torres-Larios A; Mendoza-Hernández G; Enriquez-Flores S; Castillo-Villanueva A; Mendez ST; Garcia-Torres I; Torres-Arroyo A; Gómez-Manzo S; Marcial-Quino J; Oria-Hernández J; López-Velázquez G; Reyes-Vivas H
    Biochim Biophys Acta; 2013 Dec; 1834(12):2702-11. PubMed ID: 24056040
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In silico prediction of the effects of mutations in the human triose phosphate isomerase gene: Towards a predictive framework for TPI deficiency.
    Oliver C; Timson DJ
    Eur J Med Genet; 2017 Jun; 60(6):289-298. PubMed ID: 28341520
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Generation and analysis of TPI deficiency zebrafish model.
    Sun P; Li Y; Liu F; Wang L
    Yi Chuan; 2024 Mar; 46(3):232-241. PubMed ID: 38632101
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Itavastatin and resveratrol increase triosephosphate isomerase protein in a newly identified variant of TPI deficiency.
    VanDemark AP; Hrizo SL; Eicher SL; Kowalski J; Myers TD; Pfeifer MR; Riley KN; Koeberl DD; Palladino MJ
    Dis Model Mech; 2022 May; 15(5):. PubMed ID: 35315486
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of protein quality control regulators using a Drosophila model of TPI deficiency.
    Hrizo SL; Eicher SL; Myers TD; McGrath I; Wodrich APK; Venkatesh H; Manjooran D; Swoger S; Gagnon K; Bruskin M; Lebedev MV; Zheng S; Vitantonio A; Kim S; Lamb ZJ; Vogt A; Ruzhnikov MRZ; Palladino MJ
    Neurobiol Dis; 2021 May; 152():105299. PubMed ID: 33600953
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Drosophila model of human inherited triosephosphate isomerase deficiency glycolytic enzymopathy.
    Celotto AM; Frank AC; Seigle JL; Palladino MJ
    Genetics; 2006 Nov; 174(3):1237-46. PubMed ID: 16980388
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Triosephosphate isomerase deficiency: facts and doubts.
    Orosz F; Oláh J; Ovádi J
    IUBMB Life; 2006 Dec; 58(12):703-15. PubMed ID: 17424909
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Degradation of functional triose phosphate isomerase protein underlies sugarkill pathology.
    Seigle JL; Celotto AM; Palladino MJ
    Genetics; 2008 Jun; 179(2):855-62. PubMed ID: 18458110
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct behavior of mutant triosephosphate isomerase in hemolysate and in isolated form: molecular basis of enzyme deficiency.
    Orosz F; Oláh J; Alvarez M; Keseru GM; Szabó B; Wágner G; Kovári Z; Horányi M; Baróti K; Martial JA; Hollán S; Ovádi J
    Blood; 2001 Nov; 98(10):3106-12. PubMed ID: 11698297
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Triosephosphate isomerase deficiency: new insights into an enigmatic disease.
    Orosz F; Oláh J; Ovádi J
    Biochim Biophys Acta; 2009 Dec; 1792(12):1168-74. PubMed ID: 19786097
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Newly discovered roles of triosephosphate isomerase including functions within the nucleus.
    Myers TD; Palladino MJ
    Mol Med; 2023 Jan; 29(1):18. PubMed ID: 36721084
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Triose phosphate isomerase deficiency is caused by altered dimerization--not catalytic inactivity--of the mutant enzymes.
    Ralser M; Heeren G; Breitenbach M; Lehrach H; Krobitsch S
    PLoS One; 2006 Dec; 1(1):e30. PubMed ID: 17183658
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hemolytic anemia and progressive neurologic impairment: think about triosephosphate isomerase deficiency.
    Aissa K; Kamoun F; Sfaihi L; Ghedira ES; Aloulou H; Kamoun T; Pissard S; Hachicha M
    Fetal Pediatr Pathol; 2014 Aug; 33(4):234-8. PubMed ID: 24840153
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.