128 related articles for article (PubMed ID: 25466181)
21. Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas.
Zhang L; Chen LH; Wan H; Yang R; Wang Z; Feng J; Yang S; Jones S; Wang S; Zhou W; Zhu H; Killela PJ; Zhang J; Wu Z; Li G; Hao S; Wang Y; Webb JB; Friedman HS; Friedman AH; McLendon RE; He Y; Reitman ZJ; Bigner DD; Yan H
Nat Genet; 2014 Jul; 46(7):726-30. PubMed ID: 24880341
[TBL] [Abstract][Full Text] [Related]
22. The pathophysiological significance of PPM1D and therapeutic targeting of PPM1D-mediated signaling by GSK2830371 in mantle cell lymphoma.
Kojima K; Maeda A; Yoshimura M; Nishida Y; Kimura S
Oncotarget; 2016 Oct; 7(43):69625-69637. PubMed ID: 27626308
[TBL] [Abstract][Full Text] [Related]
23. The serine-threonine protein phosphatase PPM1D is frequently activated through amplification in aggressive primary breast tumours.
Rauta J; Alarmo EL; Kauraniemi P; Karhu R; Kuukasjärvi T; Kallioniemi A
Breast Cancer Res Treat; 2006 Feb; 95(3):257-63. PubMed ID: 16254685
[TBL] [Abstract][Full Text] [Related]
24. Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon.
Burocziova M; Burdova K; Martinikova AS; Kasparek P; Kleiblova P; Danielsen SA; Borecka M; Jenikova G; Janečková L; Pavel J; Zemankova P; Schneiderova M; Schwarzova L; Ticha I; Sun XF; Jiraskova K; Liska V; Vodickova L; Vodicka P; Sedlacek R; Kleibl Z; Lothe RA; Korinek V; Macurek L
Cell Death Dis; 2019 Oct; 10(11):818. PubMed ID: 31659152
[TBL] [Abstract][Full Text] [Related]
25. Identification of differentially expressed genes after PPM1D silencing in breast cancer.
Pärssinen J; Alarmo EL; Khan S; Karhu R; Vihinen M; Kallioniemi A
Cancer Lett; 2008 Jan; 259(1):61-70. PubMed ID: 17977650
[TBL] [Abstract][Full Text] [Related]
26. PPM1D is a potential therapeutic target in ovarian clear cell carcinomas.
Tan DS; Lambros MB; Rayter S; Natrajan R; Vatcheva R; Gao Q; Marchiò C; Geyer FC; Savage K; Parry S; Fenwick K; Tamber N; Mackay A; Dexter T; Jameson C; McCluggage WG; Williams A; Graham A; Faratian D; El-Bahrawy M; Paige AJ; Gabra H; Gore ME; Zvelebil M; Lord CJ; Kaye SB; Ashworth A; Reis-Filho JS
Clin Cancer Res; 2009 Apr; 15(7):2269-80. PubMed ID: 19293255
[TBL] [Abstract][Full Text] [Related]
27. PPM1D exerts its oncogenic properties in human pancreatic cancer through multiple mechanisms.
Wu B; Guo BM; Kang J; Deng XZ; Fan YB; Zhang XP; Ai KX
Apoptosis; 2016 Mar; 21(3):365-78. PubMed ID: 26714478
[TBL] [Abstract][Full Text] [Related]
28. A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D.
Rayter S; Elliott R; Travers J; Rowlands MG; Richardson TB; Boxall K; Jones K; Linardopoulos S; Workman P; Aherne W; Lord CJ; Ashworth A
Oncogene; 2008 Feb; 27(8):1036-44. PubMed ID: 17700519
[TBL] [Abstract][Full Text] [Related]
29. p53-Independent expression of wild-type p53-induced phosphatase 1 (Wip1) in methylmethane sulfonate-treated cancer cell lines and human tumors.
Park JY; Song JY; Kim HM; Han HS; Seol HS; Jang SJ; Choi J
Int J Biochem Cell Biol; 2012 Jun; 44(6):896-904. PubMed ID: 22405851
[TBL] [Abstract][Full Text] [Related]
30. The role of PPM1D in cancer and advances in studies of its inhibitors.
Deng W; Li J; Dorrah K; Jimenez-Tapia D; Arriaga B; Hao Q; Cao W; Gao Z; Vadgama J; Wu Y
Biomed Pharmacother; 2020 May; 125():109956. PubMed ID: 32006900
[TBL] [Abstract][Full Text] [Related]
31. PP2Cdelta (Ppm1d, WIP1), an endogenous inhibitor of p38 MAPK, is regulated along with Trp53 and Cdkn2a following p38 MAPK inhibition during mouse preimplantation development.
Hickson JA; Fong B; Watson PH; Watson AJ
Mol Reprod Dev; 2007 Jul; 74(7):821-34. PubMed ID: 17219434
[TBL] [Abstract][Full Text] [Related]
32. Induction of PPM1D following DNA-damaging treatments through a conserved p53 response element coincides with a shift in the use of transcription initiation sites.
Rossi M; Demidov ON; Anderson CW; Appella E; Mazur SJ
Nucleic Acids Res; 2008 Dec; 36(22):7168-80. PubMed ID: 19015127
[TBL] [Abstract][Full Text] [Related]
33. The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair.
Lu X; Bocangel D; Nannenga B; Yamaguchi H; Appella E; Donehower LA
Mol Cell; 2004 Aug; 15(4):621-34. PubMed ID: 15327777
[TBL] [Abstract][Full Text] [Related]
34. PPM1D430, a novel alternative splicing variant of the human PPM1D, can dephosphorylate p53 and exhibits specific tissue expression.
Chuman Y; Kurihashi W; Mizukami Y; Nashimoto T; Yagi H; Sakaguchi K
J Biochem; 2009 Jan; 145(1):1-12. PubMed ID: 18845566
[TBL] [Abstract][Full Text] [Related]
35. PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy.
Hsu JI; Dayaram T; Tovy A; De Braekeleer E; Jeong M; Wang F; Zhang J; Heffernan TP; Gera S; Kovacs JJ; Marszalek JR; Bristow C; Yan Y; Garcia-Manero G; Kantarjian H; Vassiliou G; Futreal PA; Donehower LA; Takahashi K; Goodell MA
Cell Stem Cell; 2018 Nov; 23(5):700-713.e6. PubMed ID: 30388424
[TBL] [Abstract][Full Text] [Related]
36. [Function of Proto-oncogene Product PPM1D and Development of PPM1D Inhibitors for Cancer Chemotherapy].
Kamada R; Chuman Y; Kozakai Y; Sakaguchi K
Seikagaku; 2015 Oct; 87(5):531-8. PubMed ID: 26638620
[No Abstract] [Full Text] [Related]
37. Inhibitory role of cAMP on doxorubicin-induced apoptosis in pre-B ALL cells through dephosphorylation of p53 serine residues.
Safa M; Kazemi A; Zand H; Azarkeivan A; Zaker F; Hayat P
Apoptosis; 2010 Feb; 15(2):196-203. PubMed ID: 19882354
[TBL] [Abstract][Full Text] [Related]
38. Overexpression of the wip1 gene abrogates the p38 MAPK/p53/Wip1 pathway and silences p16 expression in human breast cancers.
Yu E; Ahn YS; Jang SJ; Kim MJ; Yoon HS; Gong G; Choi J
Breast Cancer Res Treat; 2007 Mar; 101(3):269-78. PubMed ID: 16897432
[TBL] [Abstract][Full Text] [Related]
39. NF-κB signaling inhibition and anticancer activities of LLDT-246 on human colorectal cancer HCT-116 cells in vitro.
Li M; Wang X; Liu M; Qi X; Li J
Biomed Pharmacother; 2014 Jun; 68(5):527-35. PubMed ID: 24986326
[TBL] [Abstract][Full Text] [Related]
40. Increased wild-type p53-induced phosphatase 1 (Wip1 or PPM1D) expression correlated with downregulation of checkpoint kinase 2 in human gastric carcinoma.
Fuku T; Semba S; Yutori H; Yokozaki H
Pathol Int; 2007 Sep; 57(9):566-71. PubMed ID: 17685927
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
