309 related articles for article (PubMed ID: 25466281)
1. Lysosomal enzyme cathepsin B enhances the aggregate forming activity of exogenous α-synuclein fibrils.
Tsujimura A; Taguchi K; Watanabe Y; Tatebe H; Tokuda T; Mizuno T; Tanaka M
Neurobiol Dis; 2015 Jan; 73():244-53. PubMed ID: 25466281
[TBL] [Abstract][Full Text] [Related]
2. C-terminal α-synuclein truncations are linked to cysteine cathepsin activity in Parkinson's disease.
McGlinchey RP; Lacy SM; Huffer KE; Tayebi N; Sidransky E; Lee JC
J Biol Chem; 2019 Jun; 294(25):9973-9984. PubMed ID: 31092553
[TBL] [Abstract][Full Text] [Related]
3. Cysteine cathepsins are essential in lysosomal degradation of α-synuclein.
McGlinchey RP; Lee JC
Proc Natl Acad Sci U S A; 2015 Jul; 112(30):9322-7. PubMed ID: 26170293
[TBL] [Abstract][Full Text] [Related]
4. Selective imaging of internalized proteopathic α-synuclein seeds in primary neurons reveals mechanistic insight into transmission of synucleinopathies.
Karpowicz RJ; Haney CM; Mihaila TS; Sandler RM; Petersson EJ; Lee VM
J Biol Chem; 2017 Aug; 292(32):13482-13497. PubMed ID: 28611062
[TBL] [Abstract][Full Text] [Related]
5. The effect of fluorescent labeling on α-synuclein fibril morphology.
Mučibabić M; Apetri MM; Canters GW; Aartsma TJ
Biochim Biophys Acta; 2016 Oct; 1864(10):1419-27. PubMed ID: 27475048
[TBL] [Abstract][Full Text] [Related]
6. Oxidative stress-induced phosphorylation, degradation and aggregation of alpha-synuclein are linked to upregulated CK2 and cathepsin D.
Takahashi M; Ko LW; Kulathingal J; Jiang P; Sevlever D; Yen SH
Eur J Neurosci; 2007 Aug; 26(4):863-74. PubMed ID: 17714183
[TBL] [Abstract][Full Text] [Related]
7. Over-expression of an inactive mutant cathepsin D increases endogenous alpha-synuclein and cathepsin B activity in SH-SY5Y cells.
Crabtree D; Dodson M; Ouyang X; Boyer-Guittaut M; Liang Q; Ballestas ME; Fineberg N; Zhang J
J Neurochem; 2014 Mar; 128(6):950-61. PubMed ID: 24138030
[TBL] [Abstract][Full Text] [Related]
8. Cathepsin K is a potent disaggregase of α-synuclein fibrils.
McGlinchey RP; Lacy SM; Walker RL; Lee JC
Biochem Biophys Res Commun; 2020 Sep; 529(4):1106-1111. PubMed ID: 32819572
[TBL] [Abstract][Full Text] [Related]
9. α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity.
Ghanem SS; Majbour NK; Vaikath NN; Ardah MT; Erskine D; Jensen NM; Fayyad M; Sudhakaran IP; Vasili E; Melachroinou K; Abdi IY; Poggiolini I; Santos P; Dorn A; Carloni P; Vekrellis K; Attems J; McKeith I; Outeiro TF; Jensen PH; El-Agnaf OMA
Proc Natl Acad Sci U S A; 2022 Apr; 119(15):e2109617119. PubMed ID: 35353605
[TBL] [Abstract][Full Text] [Related]
10. C-terminal truncation exacerbates the aggregation and cytotoxicity of α-Synuclein: A vicious cycle in Parkinson's disease.
Ma L; Yang C; Zhang X; Li Y; Wang S; Zheng L; Huang K
Biochim Biophys Acta Mol Basis Dis; 2018 Dec; 1864(12):3714-3725. PubMed ID: 30290273
[TBL] [Abstract][Full Text] [Related]
11. Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods.
Tarutani A; Arai T; Murayama S; Hisanaga SI; Hasegawa M
Acta Neuropathol Commun; 2018 Apr; 6(1):29. PubMed ID: 29669601
[TBL] [Abstract][Full Text] [Related]
12. Analysis of sheep α-synuclein provides a molecular strategy for the reduction of fibrillation.
Bickle L; Hopwood JJ; Karageorgos L
Biochim Biophys Acta Proteins Proteom; 2017 Mar; 1865(3):261-273. PubMed ID: 28007442
[TBL] [Abstract][Full Text] [Related]
13. Small molecule-based fluorescent probes for the detection of α-Synuclein aggregation states.
Haque R; Maity D
Bioorg Med Chem Lett; 2023 Apr; 86():129257. PubMed ID: 36966976
[TBL] [Abstract][Full Text] [Related]
14. Extracellular α-synuclein impairs sphingosine 1-phosphate receptor type 3 (S1PR3)-regulated lysosomal delivery of cathepsin D in HeLa cells.
Nishida S; Matovelo SA; Kajimoto T; Nakamura SI; Okada T
Genes Cells; 2024 Mar; 29(3):207-216. PubMed ID: 38163647
[TBL] [Abstract][Full Text] [Related]
15. The Molecular Chaperone DNAJB6, but Not DNAJB1, Suppresses the Seeded Aggregation of Alpha-Synuclein in Cells.
Deshayes N; Arkan S; Hansen C
Int J Mol Sci; 2019 Sep; 20(18):. PubMed ID: 31514384
[TBL] [Abstract][Full Text] [Related]
16. Impaired endo-lysosomal membrane integrity accelerates the seeding progression of α-synuclein aggregates.
Jiang P; Gan M; Yen SH; McLean PJ; Dickson DW
Sci Rep; 2017 Aug; 7(1):7690. PubMed ID: 28794446
[TBL] [Abstract][Full Text] [Related]
17. Physiological C-terminal truncation of α-synuclein potentiates the prion-like formation of pathological inclusions.
Sorrentino ZA; Vijayaraghavan N; Gorion KM; Riffe CJ; Strang KH; Caldwell J; Giasson BI
J Biol Chem; 2018 Dec; 293(49):18914-18932. PubMed ID: 30327435
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts.
Ardah MT; Ghanem SS; Abdulla SA; Lv G; Emara MM; Paleologou KE; Vaikath NN; Lu JH; Li M; Vekrellis K; Eliezer D; El-Agnaf OMA
BMC Complement Med Ther; 2020 Mar; 20(1):73. PubMed ID: 32143619
[TBL] [Abstract][Full Text] [Related]
19. A simple, versatile and robust centrifugation-based filtration protocol for the isolation and quantification of α-synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α-synuclein research.
Kumar ST; Donzelli S; Chiki A; Syed MMK; Lashuel HA
J Neurochem; 2020 Apr; 153(1):103-119. PubMed ID: 31925956
[TBL] [Abstract][Full Text] [Related]
20. α-Synuclein aggregation at low concentrations.
Afitska K; Fucikova A; Shvadchak VV; Yushchenko DA
Biochim Biophys Acta Proteins Proteom; 2019; 1867(7-8):701-709. PubMed ID: 31096048
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]